A benchmark database for variations


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Protein disorder

Dataset used for PON-Diso

DATASET 1

Disorder-related amino acid substitutions. F1 contains a test set of 101 amino acid substitutions in 31 proteins.

    Protein disorder Supplementary Table 1 (Word table)
    Protein disorder Supplementary Table 1 (tab-delimited)

Reference: Ali, H. , Urolagin, S. , Gurarslan, Ö. and Vihinen, M. (2014), Performance of Protein Disorder Prediction Programs on Amino Acid Substitutions. Human Mutation, 35: 794-804. doi:10.1002/humu.22564.   PUBMED  

DATASET 2

Dataset for IDRMutPred.Variants in intrinsically disordered regions (Zhou et al., 2020). Training data 5027 variants in 2390 proteins, test set 559 variants in 262 proteins

    F

Reference: Zhou J, Xiong Y, An K, Ye Z, Wu Y, IDRMutPred: predicting disease-associated germline nonsynonymous single nucleotide variants (nsSNVs) in intrinsically disordered regions. Bioinformatics. doi: 10.1093/bioinformatics/btaa618.   PUBMED  


Last updated: 2021-02-07 by Niloofar Shirvanizadeh.