Protein-Specific and General Pathogenicity Predictors for Amino Acid Substitutions

This dataset corresponds to the collections of pathogenic and neutral variants in 82 proteins used to compare the performance of protein-specific predictors with that of general methods (SIFT, PolyPhen-2, PON-P2, CADD, MutationAssessor2). Each of the 82 sets contains the variations from only one protein.

1. Download: Riera_dataset.txt

Reference: Riera C, Padilla N and de la Cruz X, 2016. The Complementarity Between Protein-Specific and General Pathogenicity Predictors for Amino Acid Substitutions. Hum Mutat 37:1013–1024  PUBMED