1. Variation datasets affecting protein tolerance

DATASET 7

Dataset 7 is subset of the DATASET 2 filtered by the availability of features used in PON-P2. This dataset is used for training and testing PON-P2.

PON-P2

Download: PON-P2 pathogenic training dataset

Download: PON-P2 neutral training dataset

Download: PON-P2 pathogenic test dataset

Download: PON-P2 neutral test dataset

Download: PON-P2 pathogenic c95_training dataset

Download: PON-P2 neutral c95_training dataset

Download: PON-P2 pathogenic c95_test dataset

Download: PON-P2 neutral c95_test dataset

Reference: Niroula A, Urolagin S, Vihinen M (2015) PON-P2: Prediction Method for Fast and Reliable Identification of Harmful Variants. PLoS ONE 10(2): e0117380. https://doi.org/10.1371/journal.pone.0117380.  PUBMED