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 - databases for immunodeficiency-causing variations

   AIREbase
   Variation registry for  Autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED)


Aminoacid substitutions - AIREbase

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----1--------1
F ----------1---1
I ----------0
L -----2----57
M --2-2-----------4
V 1----------4-5
W -----------21----21
Y -----------2--2
D ------------0
E -------1------1
H ------------0
K -------1-----1
R --1-2----317
N ------------0
Q ---------4----4
S -------0
T --3---------3
C ------------1-1
G ----6-------6
P --6----------17
Total 00094380010123041055771
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----1.4--------1.4
F ----------1.4---1.4
I ----------0.0
L -----2.8----7.09.9
M --2.8-2.8-----------5.6
V 1.4----------5.6-7.0
W -----------29.6----29.6
Y -----------2.8--2.8
D ------------0.0
E -------1.4------1.4
H ------------0.0
K -------1.4-----1.4
R --1.4-2.8----4.21.49.9
N ------------0.0
Q ---------5.6----5.6
S -------0.0
T --4.2---------4.2
C ------------1.4-1.4
G ----8.5-------8.5
P --8.5----------1.49.9
Total 0.00.00.012.75.64.211.30.00.01.40.01.432.40.05.61.40.07.07.09.9100.0


This site is updated by Gerard Schaafsma
© Protein Structure and Bioinformatics, Lund University, 2017
Last modified 17.04.2024