ICOSbase mutation publications [2009] [2004] [2003] Search PubMed latest citations for ICOS mutations 2009 Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients. Takahashi N, Matsumoto K, Saito H, Nanki T, Miyasaka N, Kobata T, Azuma M, Lee SK, Mizutani S, Morio T J Immunol 2009(9): 5515-27 [PubMed abstract]. 2004 ICOS deficiency in patients with common variable immunodeficiency. Salzer U, Maul-Pavicic A, Cunningham-Rundles C, Urschel S, Belohradsky BH, Litzman J, Holm A, Franco JL, Plebani A, Hammarstrom L, Skrabl A, Schwinger W, Grimbacher B Clin Immunol 2004(3): 234-40 [PubMed abstract]. 2003 Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Dräger R, Eibel H, Fischer B, Schäffer AA, Mages HW, Kroczek RA, Peter HH Nat Immunol 2003(3): 261-8 [PubMed abstract].