Immune system is a complex machinery, which is based on the highly coordinated expression of a wide array of genes and proteins. Internet resource called Immumome was constructed for the characterisation of the human immune system. Immumome contains information about immunity related proteins, their domain structure and the related ontology terms. Information can be found also about the localization of the coding genesand their comparison with the existing mouse orthologs. In addition links to the ImmTree database are also included for phylogenetic trees for orthologs from species.

Detailes of data collection can be read in our article about the database in Immunogenetics. A detailed analysis can be read also here on the evolution of the immunome genes. Please cite this article if you use Immunome database in your research:

Ortutay C, Siermala M, Vihinen M.
Molecular characterization of the immune system: emergence of proteins, processes, and domains.
Immunogenetics. doi:10.1007/s00251-007-0191-0


Table of content:

 Search for Gene Groups
Here you can search for group of genes e.g. by protein domains or ontology terms. Also list of proteins for functional categories, e.g. Cellular immunity or Complement system can be reached from here.

 Search for a single Gene
Here you can search for genes and proteins by GenBank gi numbers, accession numbers or UniProt accession numbers. Keyword search in the descriptions of proteins also implemented here.

 Supplementary Material
Supplementary material for the article describing the database and the analysis behind of that is available from here. It consists of 2 excell files summarizing the data on 7 tables.

Versions

1. Version 1.1 Open release: 24.11.2008 Number of genes: 893
2. Version 1.0 Open release: 07.01.2007 Number of genes: 847
3. Version 1.0 rc3 Restricted release: 22.09.2006 Number of genes: 847
4. Version 1.0 rc2 Restricted release: 07.06.2006 Number of genes: 652
5. Version 1.0 rc1 Restricted release: 15.12.2005 Number of genes: 554