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- databases for immunodeficiency-causing variations

   WASbase
   Variation registry for  Wiskott-Aldrich syndrome (WAS)


Aminoacid substitutions - WASbase

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----5--1------17
F -------------0
I ------2-12---5
L -1--------910
M --2-1--------1---4
V 1122-----------24
W ---------------0
Y -----------2--2
D -----1--2----5-8
E ------1-5------6
H --------1----1
K ---------2---2
R --1----91-24136
N ------------0
Q --------1-----1
S 2-------1115
T 1-1-13------1---16
C -----3--------3
G -----1--1----2
P 1---------3-22--8
Total 243235603301075503827710140
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----3.6--0.7------0.75.0
F -------------0.0
I ------1.4-0.71.4---3.6
L -0.7--------6.47.1
M --1.4-0.7--------0.7---2.9
V 0.70.715.7-----------17.1
W ---------------0.0
Y -----------1.4--1.4
D -----0.7--1.4----3.6-5.7
E ------0.7-3.6------4.3
H --------0.7----0.7
K ---------1.4---1.4
R --0.7----6.40.7-17.10.725.7
N ------------0.0
Q --------0.7-----0.7
S 1.4-------0.70.70.73.6
T 0.7-0.7-9.3------0.7---11.4
C -----2.1--------2.1
G -----0.7--0.7----1.4
P 0.7---------2.1-1.41.4--5.7
Total 1.42.92.11.425.04.30.02.12.10.07.15.03.63.60.02.15.719.35.07.1100.0