## This file contains classification of PON-mt-tRNA for all possible single nucleotide substitutions in 22 human mitochondrial tRNAs (mt-tRNAs). ## The classification is done based on predictions of 20 machine learning (random forests) predictors. ## The classification was done in September 2015. ## Visit our website http://structure.bmc.lu.se/PON-mt-tRNA/ for further information or contact us at proteinbioinformatik@med.lu.se How to cite PON-mt-tRNA? Abhishek Niroula and Mauno Vihinen PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations Nucleic Acids Res. 2016 44(5): 2020-2027. Disclaimer This non-profit server, its associated data and services are for research purposes only. The responsibility of Protein Structure and Bioinformatics Group, Lund University is limited to applying the best efforts in providing and publishing good programs and data. The developers have no responsibility for the usage of results, data or information which this server has provided. Liability In preparation of this site and service, every effort has been made to offer the most current and correct information possible. We render no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any direct, indirect, putative, special, or consequential damages arising out of any inaccuracies or omissions. In utilizing this service, individuals, organizations, and companies absolve Lund University or any of their employees or agents from responsibility for the effect of any process, method or product or that may be produced or adopted by any part, notwithstanding that the formulation of such process, method or product may be based upon information provided here. Predictions mt-tRNA mtDNA_position Reference_nucleotide New_nucleotide Classification ML_probability_of_pathogenicity Prediction_of_Kondrashov_method Ala 5655 A C Neutral 0.282437 1 Ala 5655 A G Neutral 0.171284 0 Ala 5655 A T Neutral 0.282437 1 Ala 5654 A C Neutral 0.32813 1 Ala 5654 A G Neutral 0.251853 1 Ala 5654 A T Neutral 0.32813 1 Ala 5653 G A Likely pathogenic 0.569971 1 Ala 5653 G C Likely pathogenic 0.576816 1 Ala 5653 G T Likely pathogenic 0.576816 1 Ala 5652 G A Likely pathogenic 0.662798 1 Ala 5652 G C Likely pathogenic 0.662798 1 Ala 5652 G T Likely pathogenic 0.662798 1 Ala 5651 G A Neutral 0.111034 0 Ala 5651 G C Neutral 0.230348 0 Ala 5651 G T Neutral 0.11925 0 Ala 5650 C A Likely neutral 0.421278 1 Ala 5650 C G Likely neutral 0.421278 1 Ala 5650 C T Likely neutral 0.398032 0 Ala 5649 T A Likely pathogenic 0.557289 1 Ala 5649 T C Likely pathogenic 0.557289 1 Ala 5649 T G Likely pathogenic 0.557289 1 Ala 5648 T A Pathogenic 0.687236 1 Ala 5648 T C Pathogenic 0.687236 1 Ala 5648 T G Pathogenic 0.687236 1 Ala 5647 A C Likely pathogenic 0.551845 1 Ala 5647 A G Likely pathogenic 0.551845 1 Ala 5647 A T Likely pathogenic 0.551845 1 Ala 5646 G A Pathogenic 0.857394 1 Ala 5646 G C Pathogenic 0.857394 1 Ala 5646 G T Pathogenic 0.857394 1 Ala 5645 C A Pathogenic 0.762294 1 Ala 5645 C G Pathogenic 0.762294 1 Ala 5645 C T Pathogenic 0.707162 1 Ala 5644 T A Likely pathogenic 0.557289 1 Ala 5644 T C Likely pathogenic 0.557289 1 Ala 5644 T G Likely pathogenic 0.557289 1 Ala 5643 T A Pathogenic 0.829214 1 Ala 5643 T C Pathogenic 0.829214 1 Ala 5643 T G Pathogenic 0.829214 1 Ala 5642 A C Pathogenic 0.773953 1 Ala 5642 A G Pathogenic 0.773953 1 Ala 5642 A T Pathogenic 0.773953 1 Ala 5641 A C Pathogenic 0.758972 1 Ala 5641 A G Pathogenic 0.758972 1 Ala 5641 A T Pathogenic 0.758972 1 Ala 5640 T A Neutral 0.35436 1 Ala 5640 T C Neutral 0.332296 1 Ala 5640 T G Neutral 0.285424 1 Ala 5639 T A Likely neutral 0.461596 1 Ala 5639 T C Likely neutral 0.486996 1 Ala 5639 T G Likely neutral 0.461596 1 Ala 5638 A C Neutral 0.309338 1 Ala 5638 A G Neutral 0.309338 1 Ala 5638 A T Neutral 0.209293 1 Ala 5637 A C Pathogenic 0.814917 1 Ala 5637 A G Pathogenic 0.814917 1 Ala 5637 A T Pathogenic 0.814917 1 Ala 5636 A C Likely pathogenic 0.552649 1 Ala 5636 A G Likely pathogenic 0.552649 1 Ala 5636 A T Likely pathogenic 0.552649 1 Ala 5635 G A Pathogenic 0.952477 1 Ala 5635 G C Pathogenic 0.952477 1 Ala 5635 G T Pathogenic 0.952477 1 Ala 5634 T A Neutral 0.260415 0 Ala 5634 T C Neutral 0.175808 0 Ala 5634 T G Neutral 0.260415 0 Ala 5633 G A Neutral 0.128957 0 Ala 5633 G C Neutral 0.224239 0 Ala 5633 G T Neutral 0.224239 0 Ala 5632 G A Neutral 0.142977 0 Ala 5632 G C Neutral 0.184593 0 Ala 5632 G T Neutral 0.146989 0 Ala 5631 C A Neutral 0.268488 1 Ala 5631 C G Neutral 0.320958 1 Ala 5631 C T Neutral 0.281321 0 Ala 5630 T A Likely pathogenic 0.676586 1 Ala 5630 T C Likely pathogenic 0.676586 1 Ala 5630 T G Likely pathogenic 0.676586 1 Ala 5629 G A Pathogenic 0.857104 1 Ala 5629 G C Pathogenic 0.901169 1 Ala 5629 G T Pathogenic 0.901169 1 Ala 5628 A C Likely pathogenic 0.588326 1 Ala 5628 A G Likely pathogenic 0.60086 1 Ala 5628 A T Likely pathogenic 0.588326 1 Ala 5627 T A Likely neutral 0.3961 1 Ala 5627 T C Likely neutral 0.3961 1 Ala 5627 T G Likely neutral 0.381811 1 Ala 5626 T A Likely pathogenic 0.576718 1 Ala 5626 T C Likely pathogenic 0.576718 1 Ala 5626 T G Likely pathogenic 0.576718 1 Ala 5625 T A Likely neutral 0.342678 1 Ala 5625 T C Likely neutral 0.342678 1 Ala 5625 T G Likely neutral 0.342678 1 Ala 5624 G A Likely pathogenic 0.58559 1 Ala 5624 G C Likely pathogenic 0.58559 1 Ala 5624 G T Likely pathogenic 0.58559 1 Ala 5623 C A Likely neutral 0.486682 1 Ala 5623 C G Likely neutral 0.486682 1 Ala 5623 C T Likely neutral 0.486682 1 Ala 5622 G A Neutral 0.145897 1 Ala 5622 G C Neutral 0.25211 1 Ala 5622 G T Neutral 0.25211 1 Ala 5621 T A Neutral 0.233966 1 Ala 5621 T C Neutral 0.227644 0 Ala 5621 T G Neutral 0.233966 1 Ala 5620 T A Likely neutral 0.449452 1 Ala 5620 T C Neutral 0.33859 1 Ala 5620 T G Likely neutral 0.449452 1 Ala 5619 C A Pathogenic 0.795829 1 Ala 5619 C G Pathogenic 0.795829 1 Ala 5619 C T Pathogenic 0.733342 1 Ala 5618 A C Pathogenic 0.69698 1 Ala 5618 A G Likely pathogenic 0.655597 1 Ala 5618 A T Pathogenic 0.69698 1 Ala 5617 G A Likely neutral 0.437299 0 Ala 5617 G C Likely pathogenic 0.51557 1 Ala 5617 G T Likely neutral 0.459151 1 Ala 5616 T A Neutral 0.130409 0 Ala 5616 T C Neutral 0.143598 0 Ala 5616 T G Neutral 0.122375 0 Ala 5615 T A Neutral 0.167185 1 Ala 5615 T C Neutral 0.260703 1 Ala 5615 T G Neutral 0.260703 1 Ala 5614 G A Pathogenic 0.828027 1 Ala 5614 G C Pathogenic 0.828027 1 Ala 5614 G T Pathogenic 0.828027 1 Ala 5613 A C Pathogenic 0.684314 1 Ala 5613 A G Pathogenic 0.684314 1 Ala 5613 A T Pathogenic 0.684314 1 Ala 5612 T A Likely neutral 0.388924 1 Ala 5612 T C Likely neutral 0.388924 1 Ala 5612 T G Likely neutral 0.388924 1 Ala 5611 G A Pathogenic 0.756504 0 Ala 5611 G C Pathogenic 0.756504 1 Ala 5611 G T Pathogenic 0.756504 1 Ala 5610 C A Neutral 0.323959 1 Ala 5610 C G Neutral 0.323959 1 Ala 5610 C T Neutral 0.230596 0 Ala 5609 A C Likely neutral 0.486771 1 Ala 5609 A G Neutral 0.356046 0 Ala 5609 A T Likely neutral 0.486771 1 Ala 5608 G A Likely neutral 0.471098 0 Ala 5608 G C Likely pathogenic 0.545261 0 Ala 5608 G T Likely pathogenic 0.545261 0 Ala 5607 A C Neutral 0.326177 1 Ala 5607 A G Neutral 0.251218 1 Ala 5607 A T Neutral 0.326177 1 Ala 5606 G A Neutral 0.276092 0 Ala 5606 G C Likely neutral 0.394729 0 Ala 5606 G T Neutral 0.272314 0 Ala 5605 T A Neutral 0.227455 0 Ala 5605 T C Neutral 0.13363 0 Ala 5605 T G Neutral 0.227455 0 Ala 5604 G A Neutral 0.14797 0 Ala 5604 G C Neutral 0.309338 0 Ala 5604 G T Neutral 0.193536 0 Ala 5603 G A Neutral 0.121345 0 Ala 5603 G C Neutral 0.243638 0 Ala 5603 G T Neutral 0.119398 0 Ala 5602 G A Neutral 0.172013 0 Ala 5602 G C Neutral 0.246604 0 Ala 5602 G T Neutral 0.246604 0 Ala 5601 G A Neutral 0.126794 0 Ala 5601 G C Neutral 0.288603 0 Ala 5601 G T Neutral 0.128006 0 Ala 5600 T A Neutral 0.090545 0 Ala 5600 T C Neutral 0.076182 0 Ala 5600 T G Neutral 0.078134 0 Ala 5599 T A Neutral 0.33125 1 Ala 5599 T C Neutral 0.263609 1 Ala 5599 T G Neutral 0.33125 1 Ala 5598 T A Likely neutral 0.422026 1 Ala 5598 T C Neutral 0.309963 0 Ala 5598 T G Likely neutral 0.422026 1 Ala 5597 T A Likely neutral 0.485435 1 Ala 5597 T C Likely neutral 0.482714 0 Ala 5597 T G Likely neutral 0.485435 1 Ala 5596 G A Neutral 0.296738 0 Ala 5596 G C Likely neutral 0.43271 1 Ala 5596 G T Likely neutral 0.43271 1 Ala 5595 C A Likely pathogenic 0.606306 1 Ala 5595 C G Likely pathogenic 0.606306 1 Ala 5595 C T Likely neutral 0.45988 0 Ala 5594 A C Pathogenic 0.745681 1 Ala 5594 A G Pathogenic 0.745681 1 Ala 5594 A T Pathogenic 0.745681 1 Ala 5593 G A Pathogenic 0.722952 0 Ala 5593 G C Pathogenic 0.789274 1 Ala 5593 G T Pathogenic 0.789274 1 Ala 5592 T A Likely neutral 0.438751 1 Ala 5592 T C Neutral 0.302677 0 Ala 5592 T G Likely neutral 0.438751 1 Ala 5591 C A Pathogenic 0.720907 1 Ala 5591 C G Pathogenic 0.720907 1 Ala 5591 C T Likely pathogenic 0.698818 1 Ala 5590 C A Pathogenic 0.772967 1 Ala 5590 C G Pathogenic 0.772967 1 Ala 5590 C T Pathogenic 0.74565 1 Ala 5589 T A Likely pathogenic 0.557289 1 Ala 5589 T C Likely pathogenic 0.557289 1 Ala 5589 T G Likely pathogenic 0.557289 1 Ala 5588 T A Pathogenic 0.829214 1 Ala 5588 T C Pathogenic 0.829214 0 Ala 5588 T G Pathogenic 0.829214 1 Ala 5587 A C Likely neutral 0.386061 1 Ala 5587 A G Likely neutral 0.321902 1 Ala 5587 A T Likely neutral 0.386061 1 Arg 10405 T A Likely neutral 0.439602 1 Arg 10405 T C Likely pathogenic 0.511333 1 Arg 10405 T G Likely pathogenic 0.520766 1 Arg 10406 G A Pathogenic 0.641918 1 Arg 10406 G C Pathogenic 0.769946 1 Arg 10406 G T Pathogenic 0.769946 1 Arg 10407 G A Likely pathogenic 0.525201 1 Arg 10407 G C Pathogenic 0.620361 1 Arg 10407 G T Pathogenic 0.620361 1 Arg 10408 T A Likely pathogenic 0.632928 1 Arg 10408 T C Likely pathogenic 0.563759 1 Arg 10408 T G Likely pathogenic 0.632928 1 Arg 10409 A C Pathogenic 0.849146 1 Arg 10409 A G Pathogenic 0.777208 1 Arg 10409 A T Pathogenic 0.849146 0 Arg 10410 T A Neutral 0.235434 0 Arg 10410 T C Neutral 0.173037 0 Arg 10410 T G Neutral 0.201862 0 Arg 10411 A C Likely neutral 0.450624 1 Arg 10411 A G Likely neutral 0.428791 1 Arg 10411 A T Likely pathogenic 0.550274 1 Arg 10412 T A Likely pathogenic 0.572269 1 Arg 10412 T C Likely pathogenic 0.572269 1 Arg 10412 T G Likely pathogenic 0.572269 1 Arg 10413 A C Likely pathogenic 0.592893 1 Arg 10413 A G Likely pathogenic 0.592893 1 Arg 10413 A T Likely pathogenic 0.592893 1 Arg 10414 G A Pathogenic 0.934205 0 Arg 10414 G C Pathogenic 0.950455 1 Arg 10414 G T Pathogenic 0.950455 1 Arg 10415 T A Likely pathogenic 0.58395 1 Arg 10415 T C Likely pathogenic 0.58395 1 Arg 10415 T G Likely pathogenic 0.58395 1 Arg 10416 T A Pathogenic 0.792667 1 Arg 10416 T C Pathogenic 0.775603 1 Arg 10416 T G Pathogenic 0.792667 1 Arg 10417 T A Pathogenic 0.834862 1 Arg 10417 T C Pathogenic 0.834862 1 Arg 10417 T G Pathogenic 0.834862 1 Arg 10418 A C Pathogenic 0.802708 1 Arg 10418 A G Pathogenic 0.802708 1 Arg 10418 A T Pathogenic 0.802708 1 Arg 10419 A C Pathogenic 0.707725 1 Arg 10419 A G Likely pathogenic 0.609137 1 Arg 10419 A T Likely pathogenic 0.661616 1 Arg 10420 A C Neutral 0.31541 0 Arg 10420 A G Neutral 0.312237 0 Arg 10420 A T Neutral 0.310955 0 Arg 10421 C A Neutral 0.304062 0 Arg 10421 C G Neutral 0.279994 0 Arg 10421 C T Neutral 0.245693 0 Arg 10422 A C Likely neutral 0.464802 1 Arg 10422 A G Likely pathogenic 0.573545 1 Arg 10422 A T Likely neutral 0.472035 1 Arg 10423 A C Pathogenic 0.820112 1 Arg 10423 A G Pathogenic 0.820112 1 Arg 10423 A T Pathogenic 0.820112 1 Arg 10424 A C Pathogenic 0.81073 1 Arg 10424 A G Pathogenic 0.771829 1 Arg 10424 A T Pathogenic 0.81073 1 Arg 10425 A C Pathogenic 0.733185 1 Arg 10425 A G Pathogenic 0.733185 1 Arg 10425 A T Pathogenic 0.733185 1 Arg 10426 C A Likely neutral 0.46061 1 Arg 10426 C G Likely neutral 0.46061 1 Arg 10426 C T Likely neutral 0.420811 0 Arg 10427 G A Likely neutral 0.431186 0 Arg 10427 G C Likely neutral 0.40746 0 Arg 10427 G T Neutral 0.350176 0 Arg 10428 A C Likely pathogenic 0.547422 1 Arg 10428 A G Likely neutral 0.469832 1 Arg 10428 A T Likely pathogenic 0.547422 1 Arg 10429 A C Likely pathogenic 0.540889 1 Arg 10429 A G Likely pathogenic 0.505543 1 Arg 10429 A T Likely pathogenic 0.540889 1 Arg 10430 T A Neutral 0.335015 1 Arg 10430 T C Neutral 0.335015 1 Arg 10430 T G Neutral 0.335015 1 Arg 10431 G A Pathogenic 0.931862 1 Arg 10431 G C Pathogenic 0.931862 1 Arg 10431 G T Pathogenic 0.931862 1 Arg 10432 A C Pathogenic 0.749544 1 Arg 10432 A G Pathogenic 0.690711 1 Arg 10432 A T Pathogenic 0.749544 1 Arg 10433 T A Likely pathogenic 0.576934 1 Arg 10433 T C Likely pathogenic 0.576934 1 Arg 10433 T G Likely pathogenic 0.576934 1 Arg 10434 T A Likely pathogenic 0.607506 1 Arg 10434 T C Likely pathogenic 0.607506 1 Arg 10434 T G Likely pathogenic 0.607506 1 Arg 10435 T A Likely neutral 0.463135 1 Arg 10435 T C Likely neutral 0.463135 1 Arg 10435 T G Likely neutral 0.463135 1 Arg 10436 C A Likely pathogenic 0.60126 1 Arg 10436 C G Likely pathogenic 0.60126 1 Arg 10436 C T Likely pathogenic 0.60126 1 Arg 10437 G A Pathogenic 0.698031 1 Arg 10437 G C Pathogenic 0.754763 1 Arg 10437 G T Pathogenic 0.754763 1 Arg 10438 A C Pathogenic 0.719244 1 Arg 10438 A G Pathogenic 0.719244 1 Arg 10438 A T Pathogenic 0.719244 1 Arg 10439 C A Pathogenic 0.642881 1 Arg 10439 C G Pathogenic 0.642881 1 Arg 10439 C T Pathogenic 0.642881 1 Arg 10440 T A Pathogenic 0.653205 1 Arg 10440 T C Likely pathogenic 0.56122 1 Arg 10440 T G Pathogenic 0.653205 1 Arg 10441 C A Pathogenic 0.915942 1 Arg 10441 C G Pathogenic 0.915942 1 Arg 10441 C T Pathogenic 0.915942 1 Arg 10442 A C Pathogenic 0.65028 1 Arg 10442 A G Pathogenic 0.65028 1 Arg 10442 A T Pathogenic 0.65028 1 Arg 10443 T A Likely pathogenic 0.508016 1 Arg 10443 T C Likely pathogenic 0.506197 1 Arg 10443 T G Likely pathogenic 0.527415 1 Arg 10444 T A Pathogenic 0.834862 1 Arg 10444 T C Pathogenic 0.834862 1 Arg 10444 T G Pathogenic 0.834862 1 Arg 10445 A C Pathogenic 0.639133 1 Arg 10445 A G Likely pathogenic 0.622085 1 Arg 10445 A T Pathogenic 0.639133 1 Arg 10446 A C Likely neutral 0.391897 0 Arg 10446 A G Likely neutral 0.407785 0 Arg 10446 A T Likely neutral 0.391897 0 Arg 10447 A C Pathogenic 0.766483 1 Arg 10447 A G Pathogenic 0.719875 1 Arg 10447 A T Pathogenic 0.766483 1 Arg 10448 T A Neutral 0.366649 1 Arg 10448 T C Neutral 0.359298 1 Arg 10448 T G Likely neutral 0.408182 1 Arg 10449 T A Pathogenic 0.825447 1 Arg 10449 T C Pathogenic 0.799763 1 Arg 10449 T G Pathogenic 0.825447 1 Arg 10450 A C Likely pathogenic 0.661303 1 Arg 10450 A G Likely pathogenic 0.635361 1 Arg 10450 A T Likely pathogenic 0.661303 1 Arg 10451 T A Likely neutral 0.426889 1 Arg 10451 T C Likely neutral 0.453231 1 Arg 10451 T G Likely neutral 0.426889 1 Arg 10452 G A Pathogenic 0.769486 1 Arg 10452 G C Pathogenic 0.888808 1 Arg 10452 G T Pathogenic 0.888808 1 Arg 10453 A C Likely pathogenic 0.582565 1 Arg 10453 A G Likely pathogenic 0.521444 0 Arg 10453 A T Likely pathogenic 0.52317 1 Arg 10454 T A Neutral 0.223182 0 Arg 10454 T C Neutral 0.228482 0 Arg 10454 T G Neutral 0.316002 0 Arg 10455 A C Neutral 0.094622 0 Arg 10455 A G Neutral 0.094977 0 Arg 10455 A T Neutral 0.162667 0 Arg 10456 A C Neutral 0.25976 0 Arg 10456 A G Neutral 0.197452 0 Arg 10456 A T Neutral 0.25976 0 Arg 10457 T A Neutral 0.348163 1 Arg 10457 T C Neutral 0.378142 0 Arg 10457 T G Likely neutral 0.395938 1 Arg 10458 C A Pathogenic 0.807697 1 Arg 10458 C G Pathogenic 0.807697 1 Arg 10458 C T Pathogenic 0.701418 1 Arg 10459 A C Likely pathogenic 0.616975 1 Arg 10459 A G Likely pathogenic 0.562986 1 Arg 10459 A T Likely pathogenic 0.616975 1 Arg 10460 T A Likely pathogenic 0.622872 1 Arg 10460 T C Likely pathogenic 0.602364 1 Arg 10460 T G Likely pathogenic 0.622872 1 Arg 10461 A C Pathogenic 0.850735 1 Arg 10461 A G Pathogenic 0.822338 1 Arg 10461 A T Pathogenic 0.850735 1 Arg 10462 T A Likely pathogenic 0.561784 1 Arg 10462 T C Likely neutral 0.438506 1 Arg 10462 T G Likely neutral 0.457729 1 Arg 10463 T A Neutral 0.318664 0 Arg 10463 T C Neutral 0.311335 0 Arg 10463 T G Neutral 0.308332 0 Arg 10464 T A Pathogenic 0.660464 0 Arg 10464 T C Pathogenic 0.758914 1 Arg 10464 T G Pathogenic 0.788145 1 Arg 10465 A C Likely pathogenic 0.568651 1 Arg 10465 A G Likely pathogenic 0.548324 1 Arg 10465 A T Likely pathogenic 0.568651 1 Arg 10466 C A Likely neutral 0.490431 1 Arg 10466 C G Likely neutral 0.490431 1 Arg 10466 C T Likely neutral 0.458315 1 Arg 10467 C A Pathogenic 0.771473 1 Arg 10467 C G Pathogenic 0.771473 1 Arg 10467 C T Pathogenic 0.641485 1 Arg 10468 A C Pathogenic 0.738774 1 Arg 10468 A G Pathogenic 0.738774 1 Arg 10468 A T Pathogenic 0.656383 1 Arg 10469 A C Likely pathogenic 0.614912 1 Arg 10469 A G Likely pathogenic 0.540172 1 Arg 10469 A T Likely pathogenic 0.50247 1 Asn 5729 T A Likely pathogenic 0.635233 1 Asn 5729 T C Likely pathogenic 0.635233 1 Asn 5729 T G Likely pathogenic 0.635233 1 Asn 5728 A C Likely pathogenic 0.630658 1 Asn 5728 A G Likely pathogenic 0.591783 0 Asn 5728 A T Likely pathogenic 0.630658 1 Asn 5727 G A Pathogenic 0.877708 1 Asn 5727 G C Pathogenic 0.911938 1 Asn 5727 G T Pathogenic 0.911938 1 Asn 5726 A C Pathogenic 0.722271 1 Asn 5726 A G Pathogenic 0.693126 1 Asn 5726 A T Pathogenic 0.722271 1 Asn 5725 T A Likely pathogenic 0.602123 1 Asn 5725 T C Likely pathogenic 0.571583 0 Asn 5725 T G Likely pathogenic 0.602123 1 Asn 5724 T A Likely neutral 0.442912 1 Asn 5724 T C Likely neutral 0.377419 1 Asn 5724 T G Likely neutral 0.442912 1 Asn 5723 G A Pathogenic 0.663168 0 Asn 5723 G C Pathogenic 0.781609 1 Asn 5723 G T Pathogenic 0.781609 1 Asn 5722 A C Pathogenic 0.623993 1 Asn 5722 A G Pathogenic 0.623993 1 Asn 5722 A T Pathogenic 0.623993 1 Asn 5721 A C Likely pathogenic 0.53019 1 Asn 5721 A G Likely neutral 0.489705 1 Asn 5721 A T Likely pathogenic 0.53019 1 Asn 5720 G A Pathogenic 0.740717 0 Asn 5720 G C Pathogenic 0.79802 1 Asn 5720 G T Pathogenic 0.79802 1 Asn 5719 C A Pathogenic 0.661622 1 Asn 5719 C G Pathogenic 0.661622 1 Asn 5719 C T Pathogenic 0.661622 1 Asn 5718 C A Pathogenic 0.826073 1 Asn 5718 C G Pathogenic 0.826073 1 Asn 5718 C T Pathogenic 0.826073 1 Asn 5717 A C Likely pathogenic 0.625663 0 Asn 5717 A G Likely pathogenic 0.625663 0 Asn 5717 A T Likely pathogenic 0.553224 0 Asn 5716 G A Pathogenic 0.74311 0 Asn 5716 G C Pathogenic 0.828325 1 Asn 5716 G T Pathogenic 0.789662 1 Asn 5715 T A Neutral 0.389463 1 Asn 5715 T C Likely neutral 0.407439 0 Asn 5715 T G Likely neutral 0.403568 1 Asn 5714 T A Likely neutral 0.383121 1 Asn 5714 T C Likely neutral 0.350371 1 Asn 5714 T G Neutral 0.303816 1 Asn 5713 G A Likely neutral 0.481051 1 Asn 5713 G C Pathogenic 0.618624 1 Asn 5713 G T Likely neutral 0.490952 1 Asn 5712 A C Neutral 0.350373 0 Asn 5712 A G Neutral 0.338138 0 Asn 5712 A T Neutral 0.339168 0 Asn 5711 T A Neutral 0.279434 0 Asn 5711 T C Neutral 0.304068 0 Asn 5711 T G Neutral 0.330399 0 Asn 5710 T A Likely pathogenic 0.519513 1 Asn 5710 T C Likely pathogenic 0.592281 1 Asn 5710 T G Likely pathogenic 0.592281 1 Asn 5709 A C Likely pathogenic 0.505799 1 Asn 5709 A G Likely neutral 0.425823 1 Asn 5709 A T Likely neutral 0.405446 1 Asn 5708 G A Likely neutral 0.498628 0 Asn 5708 G C Likely pathogenic 0.55821 0 Asn 5708 G T Likely pathogenic 0.535061 0 Asn 5707 G A Pathogenic 0.731459 1 Asn 5707 G C Pathogenic 0.731459 1 Asn 5707 G T Pathogenic 0.731459 1 Asn 5706 G A Pathogenic 0.883618 1 Asn 5706 G C Pathogenic 0.883618 1 Asn 5706 G T Pathogenic 0.833745 1 Asn 5705 T A Likely pathogenic 0.520264 0 Asn 5705 T C Likely neutral 0.429454 0 Asn 5705 T G Likely pathogenic 0.520264 0 Asn 5704 G A Neutral 0.196151 0 Asn 5704 G C Neutral 0.203323 0 Asn 5704 G T Neutral 0.098686 0 Asn 5703 C A Likely pathogenic 0.540476 1 Asn 5703 C G Likely pathogenic 0.577356 1 Asn 5703 C T Likely pathogenic 0.65034 1 Asn 5702 T A Likely pathogenic 0.57786 1 Asn 5702 T C Likely pathogenic 0.57786 1 Asn 5702 T G Likely pathogenic 0.57786 1 Asn 5701 T A Pathogenic 0.834862 1 Asn 5701 T C Pathogenic 0.834862 1 Asn 5701 T G Pathogenic 0.834862 1 Asn 5700 A C Likely pathogenic 0.63423 1 Asn 5700 A G Likely pathogenic 0.63423 1 Asn 5700 A T Likely pathogenic 0.63423 1 Asn 5699 G A Pathogenic 0.919015 1 Asn 5699 G C Pathogenic 0.919015 1 Asn 5699 G T Pathogenic 0.919015 1 Asn 5698 C A Pathogenic 0.727536 1 Asn 5698 C G Pathogenic 0.727536 1 Asn 5698 C T Pathogenic 0.727536 1 Asn 5697 T A Likely pathogenic 0.570362 1 Asn 5697 T C Likely pathogenic 0.570362 1 Asn 5697 T G Likely pathogenic 0.570362 1 Asn 5696 G A Pathogenic 0.758058 1 Asn 5696 G C Pathogenic 0.758058 1 Asn 5696 G T Pathogenic 0.758058 1 Asn 5695 T A Likely neutral 0.42759 1 Asn 5695 T C Likely neutral 0.42759 1 Asn 5695 T G Likely neutral 0.42759 1 Asn 5694 T A Pathogenic 0.683343 1 Asn 5694 T C Pathogenic 0.683343 1 Asn 5694 T G Pathogenic 0.683343 1 Asn 5693 A C Pathogenic 0.768982 1 Asn 5693 A G Pathogenic 0.768982 1 Asn 5693 A T Pathogenic 0.768982 1 Asn 5692 A C Likely pathogenic 0.719225 1 Asn 5692 A G Likely pathogenic 0.719225 1 Asn 5692 A T Likely pathogenic 0.719225 1 Asn 5691 C A Pathogenic 0.787219 1 Asn 5691 C G Pathogenic 0.787219 1 Asn 5691 C T Pathogenic 0.787219 1 Asn 5690 T A Pathogenic 0.682356 1 Asn 5690 T C Pathogenic 0.682356 1 Asn 5690 T G Pathogenic 0.682356 1 Asn 5689 A C Pathogenic 0.868825 1 Asn 5689 A G Pathogenic 0.868825 1 Asn 5689 A T Pathogenic 0.868825 1 Asn 5688 A C Likely neutral 0.434169 1 Asn 5688 A G Likely neutral 0.434169 1 Asn 5688 A T Likely neutral 0.434169 1 Asn 5687 G A Pathogenic 0.728455 1 Asn 5687 G C Pathogenic 0.699096 1 Asn 5687 G T Pathogenic 0.656834 1 Asn 5686 T A Neutral 0.234806 1 Asn 5686 T C Neutral 0.279429 1 Asn 5686 T G Neutral 0.210761 1 Asn 5685 G A Neutral 0.240348 0 Asn 5685 G C Neutral 0.248558 0 Asn 5685 G T Neutral 0.311377 0 Asn 5684 T A Likely neutral 0.457467 1 Asn 5684 T C Likely neutral 0.437462 1 Asn 5684 T G Likely neutral 0.492346 1 Asn 5683 T A Likely pathogenic 0.555181 1 Asn 5683 T C Likely pathogenic 0.609323 1 Asn 5683 T G Likely pathogenic 0.609323 1 Asn 5682 T A Neutral 0.269113 0 Asn 5682 T C Neutral 0.295135 0 Asn 5682 T G Likely neutral 0.329648 0 Asn 5681 G A Pathogenic 0.62996 0 Asn 5681 G C Pathogenic 0.739648 1 Asn 5681 G T Pathogenic 0.739648 1 Asn 5680 T A Likely neutral 0.463484 0 Asn 5680 T C Likely neutral 0.474282 1 Asn 5680 T G Likely pathogenic 0.575726 1 Asn 5679 G A Likely pathogenic 0.572241 1 Asn 5679 G C Pathogenic 0.693028 1 Asn 5679 G T Pathogenic 0.693028 1 Asn 5678 G A Likely pathogenic 0.610908 1 Asn 5678 G C Likely pathogenic 0.663352 1 Asn 5678 G T Likely pathogenic 0.663352 1 Asn 5677 G A Pathogenic 0.925445 1 Asn 5677 G C Pathogenic 0.925445 1 Asn 5677 G T Pathogenic 0.925445 1 Asn 5676 T A Neutral 0.178468 0 Asn 5676 T C Neutral 0.143176 0 Asn 5676 T G Neutral 0.173953 0 Asn 5675 T A Neutral 0.258535 1 Asn 5675 T C Neutral 0.336585 1 Asn 5675 T G Neutral 0.267397 1 Asn 5674 T A Neutral 0.339423 0 Asn 5674 T C Neutral 0.299839 0 Asn 5674 T G Neutral 0.301684 0 Asn 5673 A C Neutral 0.220274 0 Asn 5673 A G Neutral 0.250539 0 Asn 5673 A T Neutral 0.295745 0 Asn 5672 A C Neutral 0.319542 0 Asn 5672 A G Neutral 0.262874 0 Asn 5672 A T Neutral 0.284521 0 Asn 5671 G A Likely neutral 0.393639 0 Asn 5671 G C Likely neutral 0.436936 0 Asn 5671 G T Neutral 0.331551 0 Asn 5670 T A Likely neutral 0.363497 0 Asn 5670 T C Neutral 0.325124 0 Asn 5670 T G Neutral 0.332711 0 Asn 5669 C A Pathogenic 0.765499 1 Asn 5669 C G Pathogenic 0.765499 1 Asn 5669 C T Pathogenic 0.765499 1 Asn 5668 C A Likely pathogenic 0.614331 1 Asn 5668 C G Likely pathogenic 0.614331 1 Asn 5668 C T Likely pathogenic 0.599264 1 Asn 5667 C A Pathogenic 0.695672 1 Asn 5667 C G Pathogenic 0.695672 1 Asn 5667 C T Likely pathogenic 0.573955 1 Asn 5666 A C Likely neutral 0.405413 1 Asn 5666 A G Neutral 0.326855 1 Asn 5666 A T Neutral 0.375563 0 Asn 5665 T A Likely neutral 0.380321 0 Asn 5665 T C Likely neutral 0.449346 0 Asn 5665 T G Likely neutral 0.380321 0 Asn 5664 T A Neutral 0.262011 0 Asn 5664 T C Neutral 0.30651 0 Asn 5664 T G Neutral 0.262011 0 Asn 5663 G A Neutral 0.3473 0 Asn 5663 G C Neutral 0.329608 0 Asn 5663 G T Neutral 0.235199 0 Asn 5662 G A Likely neutral 0.473048 0 Asn 5662 G C Likely neutral 0.471328 0 Asn 5662 G T Likely neutral 0.471328 0 Asn 5661 T A Pathogenic 0.728295 1 Asn 5661 T C Likely pathogenic 0.589277 1 Asn 5661 T G Pathogenic 0.728295 1 Asn 5660 C A Pathogenic 0.876773 1 Asn 5660 C G Pathogenic 0.876773 1 Asn 5660 C T Pathogenic 0.856494 1 Asn 5659 T A Pathogenic 0.682356 1 Asn 5659 T C Pathogenic 0.682356 0 Asn 5659 T G Pathogenic 0.682356 1 Asn 5658 A C Likely pathogenic 0.63423 1 Asn 5658 A G Likely pathogenic 0.63423 1 Asn 5658 A T Likely pathogenic 0.63423 1 Asn 5657 G A Pathogenic 0.826259 1 Asn 5657 G C Pathogenic 0.826259 1 Asn 5657 G T Pathogenic 0.826259 1 Asp 7518 A C Likely neutral 0.388024 1 Asp 7518 A G Likely neutral 0.313655 0 Asp 7518 A T Likely neutral 0.335988 1 Asp 7519 A C Likely neutral 0.370474 1 Asp 7519 A G Likely neutral 0.370474 1 Asp 7519 A T Likely neutral 0.370474 1 Asp 7520 G A Likely neutral 0.406763 1 Asp 7520 G C Likely neutral 0.454536 1 Asp 7520 G T Likely neutral 0.454536 1 Asp 7521 G A Likely neutral 0.457566 0 Asp 7521 G C Likely neutral 0.459094 0 Asp 7521 G T Likely neutral 0.459094 0 Asp 7522 T A Likely pathogenic 0.561343 1 Asp 7522 T C Likely pathogenic 0.561343 1 Asp 7522 T G Likely pathogenic 0.561343 1 Asp 7523 A C Pathogenic 0.639598 1 Asp 7523 A G Likely pathogenic 0.610183 1 Asp 7523 A T Likely pathogenic 0.610183 1 Asp 7524 T A Likely neutral 0.47058 1 Asp 7524 T C Likely neutral 0.385119 1 Asp 7524 T G Likely neutral 0.47058 1 Asp 7525 T A Likely pathogenic 0.600464 1 Asp 7525 T C Likely pathogenic 0.600464 1 Asp 7525 T G Likely pathogenic 0.600464 1 Asp 7526 A C Likely neutral 0.468085 1 Asp 7526 A G Likely neutral 0.468085 1 Asp 7526 A T Likely neutral 0.468085 1 Asp 7527 G A Pathogenic 0.874793 0 Asp 7527 G C Pathogenic 0.874793 1 Asp 7527 G T Pathogenic 0.874793 1 Asp 7528 A C Neutral 0.254152 1 Asp 7528 A G Neutral 0.254152 1 Asp 7528 A T Neutral 0.216443 1 Asp 7529 A C Pathogenic 0.771652 1 Asp 7529 A G Pathogenic 0.771652 1 Asp 7529 A T Pathogenic 0.771652 1 Asp 7530 A C Pathogenic 0.771652 1 Asp 7530 A G Pathogenic 0.771652 1 Asp 7530 A T Pathogenic 0.771652 1 Asp 7531 A C Likely pathogenic 0.616555 1 Asp 7531 A G Likely pathogenic 0.616555 1 Asp 7531 A T Likely pathogenic 0.616555 1 Asp 7532 A C Likely neutral 0.497508 1 Asp 7532 A G Likely neutral 0.389413 1 Asp 7532 A T Likely neutral 0.497508 1 Asp 7533 C A Neutral 0.093985 0 Asp 7533 C G Neutral 0.212427 0 Asp 7533 C T Neutral 0.108571 0 Asp 7534 C A Neutral 0.341529 0 Asp 7534 C G Neutral 0.342177 0 Asp 7534 C T Neutral 0.22588 0 Asp 7535 A C Neutral 0.190841 1 Asp 7535 A G Neutral 0.190841 1 Asp 7535 A T Neutral 0.190841 1 Asp 7536 T A Likely pathogenic 0.603319 1 Asp 7536 T C Likely pathogenic 0.605308 1 Asp 7536 T G Likely pathogenic 0.605308 1 Asp 7537 T A Pathogenic 0.742435 1 Asp 7537 T C Pathogenic 0.742435 1 Asp 7537 T G Pathogenic 0.742435 1 Asp 7538 T A Neutral 0.253391 1 Asp 7538 T C Neutral 0.314016 1 Asp 7538 T G Neutral 0.314016 1 Asp 7539 C A Pathogenic 0.88991 1 Asp 7539 C G Pathogenic 0.88991 1 Asp 7539 C T Pathogenic 0.88991 0 Asp 7540 A C Likely neutral 0.436136 1 Asp 7540 A G Likely neutral 0.413631 0 Asp 7540 A T Likely neutral 0.436136 1 Asp 7541 T A Likely pathogenic 0.582519 1 Asp 7541 T C Likely pathogenic 0.582519 1 Asp 7541 T G Likely pathogenic 0.582519 1 Asp 7542 A C Likely pathogenic 0.530755 1 Asp 7542 A G Likely neutral 0.415402 1 Asp 7542 A T Likely pathogenic 0.530755 1 Asp 7543 A C Likely neutral 0.481338 1 Asp 7543 A G Likely neutral 0.324739 1 Asp 7543 A T Likely neutral 0.481338 1 Asp 7544 C A Likely pathogenic 0.593897 1 Asp 7544 C G Likely pathogenic 0.593897 1 Asp 7544 C T Likely pathogenic 0.51373 1 Asp 7545 T A Likely neutral 0.467816 1 Asp 7545 T C Likely neutral 0.422755 1 Asp 7545 T G Likely neutral 0.467816 1 Asp 7546 T A Likely pathogenic 0.527095 1 Asp 7546 T C Likely pathogenic 0.527095 1 Asp 7546 T G Likely pathogenic 0.527095 1 Asp 7547 T A Neutral 0.287255 1 Asp 7547 T C Neutral 0.176658 1 Asp 7547 T G Neutral 0.287255 1 Asp 7548 G A Pathogenic 0.71321 1 Asp 7548 G C Pathogenic 0.71321 1 Asp 7548 G T Pathogenic 0.71321 1 Asp 7549 T A Likely pathogenic 0.520196 1 Asp 7549 T C Likely pathogenic 0.520196 1 Asp 7549 T G Likely pathogenic 0.520196 1 Asp 7550 C A Pathogenic 0.794856 1 Asp 7550 C G Pathogenic 0.794856 1 Asp 7550 C T Pathogenic 0.794856 1 Asp 7551 A C Likely neutral 0.425374 1 Asp 7551 A G Likely neutral 0.320812 1 Asp 7551 A T Likely neutral 0.425374 1 Asp 7552 A C Likely pathogenic 0.530556 1 Asp 7552 A G Likely neutral 0.487836 1 Asp 7552 A T Likely pathogenic 0.530556 1 Asp 7553 A C Neutral 0.327324 1 Asp 7553 A G Neutral 0.249866 1 Asp 7553 A T Neutral 0.327324 1 Asp 7554 G A Pathogenic 0.864244 1 Asp 7554 G C Pathogenic 0.894033 1 Asp 7554 G T Pathogenic 0.894033 1 Asp 7555 T A Likely neutral 0.358113 1 Asp 7555 T C Neutral 0.305211 1 Asp 7555 T G Likely neutral 0.358113 1 Asp 7556 T A Pathogenic 0.666281 1 Asp 7556 T C Likely pathogenic 0.592569 1 Asp 7556 T G Pathogenic 0.666281 1 Asp 7557 A C Pathogenic 0.777675 1 Asp 7557 A G Pathogenic 0.777675 1 Asp 7557 A T Pathogenic 0.777675 1 Asp 7558 A C Likely neutral 0.411662 1 Asp 7558 A G Likely neutral 0.411662 1 Asp 7558 A T Likely neutral 0.411662 1 Asp 7559 A C Neutral 0.21873 0 Asp 7559 A G Neutral 0.172682 0 Asp 7559 A T Neutral 0.160635 0 Asp 7560 T A Likely neutral 0.488874 1 Asp 7560 T C Likely neutral 0.488874 1 Asp 7560 T G Likely neutral 0.488874 1 Asp 7561 T A Likely neutral 0.446403 1 Asp 7561 T C Neutral 0.329043 1 Asp 7561 T G Likely neutral 0.446403 1 Asp 7562 A C Pathogenic 0.78682 1 Asp 7562 A G Pathogenic 0.78682 1 Asp 7562 A T Pathogenic 0.78682 1 Asp 7563 T A Likely neutral 0.398556 0 Asp 7563 T C Likely neutral 0.345623 1 Asp 7563 T G Likely neutral 0.398556 1 Asp 7564 A C Likely neutral 0.419818 1 Asp 7564 A G Neutral 0.313198 0 Asp 7564 A T Likely neutral 0.382823 1 Asp 7565 G A Likely neutral 0.348522 0 Asp 7565 G C Likely neutral 0.416914 1 Asp 7565 G T Likely neutral 0.416914 1 Asp 7566 G A Neutral 0.339361 1 Asp 7566 G C Likely neutral 0.453763 1 Asp 7566 G T Likely neutral 0.453763 1 Asp 7567 C A Neutral 0.12425 0 Asp 7567 C G Neutral 0.242021 0 Asp 7567 C T Neutral 0.171571 0 Asp 7568 T A Neutral 0.167682 0 Asp 7568 T C Neutral 0.124802 0 Asp 7568 T G Neutral 0.219653 0 Asp 7569 A C Likely neutral 0.402496 0 Asp 7569 A G Likely neutral 0.366256 0 Asp 7569 A T Neutral 0.304997 0 Asp 7570 A C Likely neutral 0.317531 0 Asp 7570 A G Likely neutral 0.39397 0 Asp 7570 A T Neutral 0.283522 0 Asp 7571 A C Neutral 0.158365 0 Asp 7571 A G Neutral 0.28164 0 Asp 7571 A T Neutral 0.207748 0 Asp 7572 T A Neutral 0.158947 0 Asp 7572 T C Neutral 0.17316 0 Asp 7572 T G Neutral 0.191235 0 Asp 7573 C A Likely neutral 0.479604 1 Asp 7573 C G Likely neutral 0.479604 1 Asp 7573 C T Likely neutral 0.366149 1 Asp 7574 C A Likely pathogenic 0.542752 1 Asp 7574 C G Likely pathogenic 0.542752 1 Asp 7574 C T Likely pathogenic 0.505954 0 Asp 7575 T A Likely pathogenic 0.51136 1 Asp 7575 T C Likely neutral 0.489436 0 Asp 7575 T G Likely pathogenic 0.51136 1 Asp 7576 A C Neutral 0.301755 1 Asp 7576 A G Neutral 0.203007 1 Asp 7576 A T Neutral 0.219956 0 Asp 7577 T A Likely pathogenic 0.582519 1 Asp 7577 T C Likely pathogenic 0.582519 1 Asp 7577 T G Likely pathogenic 0.582519 1 Asp 7578 A C Likely pathogenic 0.512749 1 Asp 7578 A G Likely neutral 0.404472 1 Asp 7578 A T Likely pathogenic 0.512749 1 Asp 7579 T A Likely pathogenic 0.582519 1 Asp 7579 T C Likely pathogenic 0.582519 1 Asp 7579 T G Likely pathogenic 0.582519 1 Asp 7580 A C Pathogenic 0.711124 1 Asp 7580 A G Pathogenic 0.682377 1 Asp 7580 A T Pathogenic 0.711124 1 Asp 7581 T A Likely neutral 0.424784 0 Asp 7581 T C Likely neutral 0.424784 0 Asp 7581 T G Likely neutral 0.424784 0 Asp 7582 C A Pathogenic 0.832805 1 Asp 7582 C G Pathogenic 0.832805 1 Asp 7582 C T Pathogenic 0.808497 1 Asp 7583 T A Likely pathogenic 0.528246 1 Asp 7583 T C Likely pathogenic 0.528246 1 Asp 7583 T G Likely pathogenic 0.528246 1 Asp 7584 T A Likely pathogenic 0.530955 1 Asp 7584 T C Likely neutral 0.39198 0 Asp 7584 T G Likely pathogenic 0.530955 1 Asp 7585 A C Neutral 0.096765 0 Asp 7585 A G Neutral 0.213403 0 Asp 7585 A T Neutral 0.087485 0 Cys 5826 A C Likely neutral 0.486131 1 Cys 5826 A G Likely neutral 0.379215 0 Cys 5826 A T Likely neutral 0.486131 1 Cys 5825 G A Pathogenic 0.916975 1 Cys 5825 G C Pathogenic 0.916975 1 Cys 5825 G T Pathogenic 0.916975 1 Cys 5824 C A Likely neutral 0.498102 1 Cys 5824 C G Likely neutral 0.498102 1 Cys 5824 C T Likely neutral 0.458938 0 Cys 5823 T A Likely neutral 0.39442 0 Cys 5823 T C Likely neutral 0.411586 0 Cys 5823 T G Likely neutral 0.39442 0 Cys 5822 C A Likely neutral 0.490106 1 Cys 5822 C G Likely neutral 0.490106 1 Cys 5822 C T Likely neutral 0.43664 0 Cys 5821 C A Neutral 0.231694 1 Cys 5821 C G Neutral 0.231694 1 Cys 5821 C T Neutral 0.136859 0 Cys 5820 G A Likely neutral 0.460301 1 Cys 5820 G C Likely pathogenic 0.598001 1 Cys 5820 G T Likely pathogenic 0.598001 1 Cys 5819 A C Likely pathogenic 0.565549 1 Cys 5819 A G Likely pathogenic 0.565549 1 Cys 5819 A T Likely neutral 0.499752 1 Cys 5818 G A Likely neutral 0.336002 0 Cys 5818 G C Likely neutral 0.38805 0 Cys 5818 G T Likely neutral 0.38805 0 Cys 5817 G A Pathogenic 0.803719 1 Cys 5817 G C Pathogenic 0.803719 1 Cys 5817 G T Pathogenic 0.803719 1 Cys 5816 T A Likely pathogenic 0.62239 1 Cys 5816 T C Likely pathogenic 0.62239 1 Cys 5816 T G Likely pathogenic 0.62239 1 Cys 5815 G A Pathogenic 0.93127 1 Cys 5815 G C Pathogenic 0.93127 1 Cys 5815 G T Pathogenic 0.93127 1 Cys 5814 A C Likely pathogenic 0.611163 1 Cys 5814 A G Likely pathogenic 0.583707 1 Cys 5814 A T Likely pathogenic 0.583958 0 Cys 5813 T A Neutral 0.113582 0 Cys 5813 T C Neutral 0.212305 0 Cys 5813 T G Neutral 0.212305 0 Cys 5812 T A Neutral 0.12831 1 Cys 5812 T C Neutral 0.12831 1 Cys 5812 T G Neutral 0.154222 1 Cys 5811 T A Neutral 0.132894 0 Cys 5811 T C Neutral 0.235367 0 Cys 5811 T G Neutral 0.235367 0 Cys 5810 T A Likely neutral 0.465272 0 Cys 5810 T C Likely neutral 0.465272 1 Cys 5810 T G Likely neutral 0.485306 1 Cys 5809 C A Pathogenic 0.909803 1 Cys 5809 C G Pathogenic 0.909803 1 Cys 5809 C T Pathogenic 0.909803 1 Cys 5808 A C Likely pathogenic 0.631934 1 Cys 5808 A G Likely pathogenic 0.631934 1 Cys 5808 A T Likely pathogenic 0.631934 1 Cys 5807 T A Likely neutral 0.409756 0 Cys 5807 T C Neutral 0.330272 0 Cys 5807 T G Likely neutral 0.409756 0 Cys 5806 A C Neutral 0.228446 0 Cys 5806 A G Neutral 0.188677 0 Cys 5806 A T Neutral 0.228446 0 Cys 5805 T A Pathogenic 0.715167 1 Cys 5805 T C Pathogenic 0.715167 1 Cys 5805 T G Pathogenic 0.715167 1 Cys 5804 T A Neutral 0.283031 0 Cys 5804 T C Neutral 0.170545 0 Cys 5804 T G Neutral 0.283031 0 Cys 5803 G A Pathogenic 0.857104 1 Cys 5803 G C Pathogenic 0.901169 1 Cys 5803 G T Pathogenic 0.901169 1 Cys 5802 A C Likely neutral 0.415675 1 Cys 5802 A G Neutral 0.327239 1 Cys 5802 A T Likely neutral 0.415675 1 Cys 5801 A C Pathogenic 0.883127 1 Cys 5801 A G Pathogenic 0.883127 1 Cys 5801 A T Pathogenic 0.883127 1 Cys 5800 T A Likely neutral 0.470953 1 Cys 5800 T C Likely neutral 0.459016 1 Cys 5800 T G Likely neutral 0.470953 1 Cys 5799 T A Likely neutral 0.342678 1 Cys 5799 T C Likely neutral 0.342678 1 Cys 5799 T G Likely neutral 0.342678 1 Cys 5798 G A Likely pathogenic 0.58559 1 Cys 5798 G C Likely pathogenic 0.58559 1 Cys 5798 G T Likely pathogenic 0.58559 1 Cys 5797 C A Pathogenic 0.686324 1 Cys 5797 C G Pathogenic 0.686324 1 Cys 5797 C T Pathogenic 0.686324 1 Cys 5796 A C Likely pathogenic 0.643438 1 Cys 5796 A G Likely pathogenic 0.643438 1 Cys 5796 A T Likely pathogenic 0.643438 1 Cys 5795 A C Pathogenic 0.69395 1 Cys 5795 A G Pathogenic 0.69395 1 Cys 5795 A T Pathogenic 0.69395 1 Cys 5794 A C Likely neutral 0.491683 1 Cys 5794 A G Likely neutral 0.39811 1 Cys 5794 A T Likely neutral 0.491683 1 Cys 5793 T A Pathogenic 0.715167 1 Cys 5793 T C Pathogenic 0.715167 1 Cys 5793 T G Pathogenic 0.715167 1 Cys 5792 T A Likely pathogenic 0.530851 1 Cys 5792 T C Likely pathogenic 0.530851 1 Cys 5792 T G Likely pathogenic 0.530851 1 Cys 5791 C A Pathogenic 0.663036 1 Cys 5791 C G Pathogenic 0.663036 1 Cys 5791 C T Likely pathogenic 0.640334 1 Cys 5790 G A Neutral 0.188187 0 Cys 5790 G C Neutral 0.298306 0 Cys 5790 G T Neutral 0.298306 0 Cys 5789 A C Likely neutral 0.415675 1 Cys 5789 A G Neutral 0.327239 1 Cys 5789 A T Likely neutral 0.415675 1 Cys 5788 A C Likely neutral 0.468177 1 Cys 5788 A G Likely neutral 0.468177 1 Cys 5788 A T Likely neutral 0.468177 1 Cys 5787 G A Pathogenic 0.710738 1 Cys 5787 G C Pathogenic 0.762333 1 Cys 5787 G T Pathogenic 0.762333 1 Cys 5786 A C Neutral 0.288055 0 Cys 5786 A G Neutral 0.270154 0 Cys 5786 A T Neutral 0.288055 0 Cys 5785 A C Likely neutral 0.401214 1 Cys 5785 A G Likely neutral 0.401214 1 Cys 5785 A T Neutral 0.29768 1 Cys 5784 G A Pathogenic 0.916975 1 Cys 5784 G C Pathogenic 0.916975 1 Cys 5784 G T Pathogenic 0.916975 1 Cys 5783 C A Likely pathogenic 0.52977 1 Cys 5783 C G Likely pathogenic 0.52977 1 Cys 5783 C T Likely neutral 0.409562 1 Cys 5782 A C Pathogenic 0.745681 1 Cys 5782 A G Pathogenic 0.745681 1 Cys 5782 A T Pathogenic 0.745681 1 Cys 5781 G A Pathogenic 0.916975 1 Cys 5781 G C Pathogenic 0.916975 1 Cys 5781 G T Pathogenic 0.916975 1 Cys 5780 C A Neutral 0.133138 0 Cys 5780 C G Neutral 0.235189 0 Cys 5780 C T Neutral 0.124037 0 Cys 5779 T A Neutral 0.208393 0 Cys 5779 T C Neutral 0.196451 0 Cys 5779 T G Neutral 0.191223 0 Cys 5778 T A Neutral 0.163925 0 Cys 5778 T C Neutral 0.215968 0 Cys 5778 T G Neutral 0.269859 0 Cys 5777 C A Neutral 0.276402 0 Cys 5777 C G Neutral 0.344635 0 Cys 5777 C T Neutral 0.210185 0 Cys 5776 A C Likely neutral 0.408809 0 Cys 5776 A G Likely neutral 0.408809 0 Cys 5776 A T Likely neutral 0.349687 0 Cys 5775 A C Neutral 0.230533 0 Cys 5775 A G Neutral 0.172273 0 Cys 5775 A T Neutral 0.205645 0 Cys 5774 A C Neutral 0.2018 0 Cys 5774 A G Neutral 0.207099 0 Cys 5774 A T Neutral 0.197525 0 Cys 5773 C A Neutral 0.155279 0 Cys 5773 C G Neutral 0.155279 0 Cys 5773 C T Neutral 0.130184 0 Cys 5772 C A Likely pathogenic 0.564006 1 Cys 5772 C G Likely pathogenic 0.564006 1 Cys 5772 C T Likely pathogenic 0.518008 1 Cys 5771 T A Likely pathogenic 0.590016 1 Cys 5771 T C Likely pathogenic 0.590016 1 Cys 5771 T G Likely pathogenic 0.590016 1 Cys 5770 G A Neutral 0.318627 1 Cys 5770 G C Likely neutral 0.433541 1 Cys 5770 G T Likely neutral 0.433541 1 Cys 5769 C A Likely pathogenic 0.640928 1 Cys 5769 C G Likely pathogenic 0.640928 1 Cys 5769 C T Likely pathogenic 0.640928 1 Cys 5768 C A Likely neutral 0.399174 1 Cys 5768 C G Likely neutral 0.399174 1 Cys 5768 C T Neutral 0.289366 1 Cys 5767 G A Likely neutral 0.383317 0 Cys 5767 G C Likely neutral 0.447011 1 Cys 5767 G T Likely neutral 0.447011 1 Cys 5766 G A Neutral 0.271509 0 Cys 5766 G C Likely neutral 0.410634 1 Cys 5766 G T Likely neutral 0.410634 1 Cys 5765 G A Likely neutral 0.449438 1 Cys 5765 G C Likely neutral 0.49819 1 Cys 5765 G T Likely neutral 0.49819 1 Cys 5764 G A Neutral 0.37011 0 Cys 5764 G C Likely neutral 0.462958 1 Cys 5764 G T Likely neutral 0.462958 1 Cys 5763 C A Pathogenic 0.825152 1 Cys 5763 C G Pathogenic 0.825152 1 Cys 5763 C T Pathogenic 0.825152 1 Cys 5762 T A Likely pathogenic 0.557289 1 Cys 5762 T C Likely pathogenic 0.557289 0 Cys 5762 T G Likely pathogenic 0.557289 1 Cys 5761 T A Likely neutral 0.415688 1 Cys 5761 T C Likely neutral 0.415688 1 Cys 5761 T G Likely neutral 0.415688 1 Gln 4400 T A Pathogenic 0.775779 1 Gln 4400 T C Pathogenic 0.775779 1 Gln 4400 T G Pathogenic 0.775779 1 Gln 4399 A C Likely pathogenic 0.532888 1 Gln 4399 A G Likely pathogenic 0.507228 1 Gln 4399 A T Likely pathogenic 0.532888 1 Gln 4398 G A Likely pathogenic 0.566028 1 Gln 4398 G C Likely pathogenic 0.566028 1 Gln 4398 G T Likely pathogenic 0.566028 1 Gln 4397 G A Neutral 0.253298 0 Gln 4397 G C Neutral 0.3313 1 Gln 4397 G T Neutral 0.3313 1 Gln 4396 A C Likely pathogenic 0.575498 1 Gln 4396 A G Likely pathogenic 0.529987 1 Gln 4396 A T Likely pathogenic 0.575498 0 Gln 4395 T A Neutral 0.265717 0 Gln 4395 T C Neutral 0.218601 0 Gln 4395 T G Neutral 0.265717 0 Gln 4394 G A Neutral 0.087123 0 Gln 4394 G C Neutral 0.192708 0 Gln 4394 G T Neutral 0.08572 0 Gln 4393 G A Neutral 0.14246 0 Gln 4393 G C Neutral 0.251134 0 Gln 4393 G T Neutral 0.157942 0 Gln 4392 G A Neutral 0.20511 0 Gln 4392 G C Neutral 0.301383 0 Gln 4392 G T Neutral 0.244746 0 Gln 4391 G A Pathogenic 0.900271 1 Gln 4391 G C Pathogenic 0.900271 1 Gln 4391 G T Pathogenic 0.900271 1 Gln 4390 T A Likely pathogenic 0.549888 1 Gln 4390 T C Likely pathogenic 0.549888 1 Gln 4390 T G Likely pathogenic 0.549888 1 Gln 4389 G A Pathogenic 0.899313 1 Gln 4389 G C Pathogenic 0.899313 1 Gln 4389 G T Pathogenic 0.899313 1 Gln 4388 T A Likely neutral 0.458506 1 Gln 4388 T C Likely neutral 0.438904 1 Gln 4388 T G Likely neutral 0.458506 1 Gln 4387 G A Neutral 0.206972 0 Gln 4387 G C Neutral 0.324113 0 Gln 4387 G T Neutral 0.232535 0 Gln 4386 A C Neutral 0.276041 0 Gln 4386 A G Neutral 0.180043 0 Gln 4386 A T Neutral 0.150774 0 Gln 4385 T A Neutral 0.129274 0 Gln 4385 T C Neutral 0.173375 0 Gln 4385 T G Neutral 0.144356 0 Gln 4384 A C Neutral 0.254638 0 Gln 4384 A G Neutral 0.118071 0 Gln 4384 A T Neutral 0.115475 0 Gln 4383 G A Likely neutral 0.369845 1 Gln 4383 G C Likely neutral 0.369845 1 Gln 4383 G T Likely neutral 0.369845 1 Gln 4382 G A Pathogenic 0.694097 1 Gln 4382 G C Pathogenic 0.694097 1 Gln 4382 G T Pathogenic 0.694097 1 Gln 4381 T A Likely neutral 0.350222 1 Gln 4381 T C Likely neutral 0.350222 1 Gln 4381 T G Likely neutral 0.350222 1 Gln 4380 G A Neutral 0.307299 0 Gln 4380 G C Neutral 0.32369 0 Gln 4380 G T Neutral 0.32369 0 Gln 4379 G A Likely pathogenic 0.543646 0 Gln 4379 G C Likely pathogenic 0.543646 0 Gln 4379 G T Likely pathogenic 0.543646 0 Gln 4378 C A Pathogenic 0.738289 1 Gln 4378 C G Pathogenic 0.738289 1 Gln 4378 C T Pathogenic 0.738289 1 Gln 4377 A C Likely pathogenic 0.611173 1 Gln 4377 A G Likely pathogenic 0.611173 1 Gln 4377 A T Likely pathogenic 0.611173 1 Gln 4376 C A Likely pathogenic 0.585113 1 Gln 4376 C G Likely pathogenic 0.585113 1 Gln 4376 C T Likely pathogenic 0.585113 1 Gln 4375 G A Likely neutral 0.416193 1 Gln 4375 G C Likely neutral 0.434836 1 Gln 4375 G T Likely neutral 0.434836 1 Gln 4374 G A Neutral 0.186468 0 Gln 4374 G C Neutral 0.316298 1 Gln 4374 G T Neutral 0.316298 1 Gln 4373 A C Likely neutral 0.425147 1 Gln 4373 A G Neutral 0.266233 1 Gln 4373 A T Likely neutral 0.425147 1 Gln 4372 G A Pathogenic 0.894294 1 Gln 4372 G C Pathogenic 0.894294 1 Gln 4372 G T Pathogenic 0.894294 1 Gln 4371 A C Likely neutral 0.393671 1 Gln 4371 A G Likely neutral 0.32814 0 Gln 4371 A T Likely neutral 0.393671 1 Gln 4370 A C Likely pathogenic 0.620088 1 Gln 4370 A G Likely pathogenic 0.552936 0 Gln 4370 A T Likely pathogenic 0.552936 0 Gln 4369 T A Neutral 0.113466 0 Gln 4369 T C Neutral 0.134563 0 Gln 4369 T G Neutral 0.1038 0 Gln 4368 T A Likely pathogenic 0.527095 1 Gln 4368 T C Likely pathogenic 0.527095 1 Gln 4368 T G Likely pathogenic 0.527095 1 Gln 4367 T A Likely pathogenic 0.527095 1 Gln 4367 T C Likely pathogenic 0.527095 1 Gln 4367 T G Likely pathogenic 0.527095 1 Gln 4366 T A Likely neutral 0.323294 1 Gln 4366 T C Likely neutral 0.323294 1 Gln 4366 T G Likely neutral 0.323294 1 Gln 4365 G A Likely pathogenic 0.558385 1 Gln 4365 G C Likely pathogenic 0.558385 1 Gln 4365 G T Likely pathogenic 0.558385 1 Gln 4364 G A Neutral 0.211299 0 Gln 4364 G C Neutral 0.295015 0 Gln 4364 G T Neutral 0.295015 0 Gln 4363 A C Neutral 0.281228 0 Gln 4363 A G Neutral 0.194086 0 Gln 4363 A T Neutral 0.281228 0 Gln 4362 T A Likely pathogenic 0.597554 0 Gln 4362 T C Likely pathogenic 0.602127 0 Gln 4362 T G Likely pathogenic 0.602127 1 Gln 4361 T A Likely neutral 0.491882 1 Gln 4361 T C Likely neutral 0.433771 0 Gln 4361 T G Likely neutral 0.491882 1 Gln 4360 C A Pathogenic 0.872772 1 Gln 4360 C G Pathogenic 0.872772 1 Gln 4360 C T Pathogenic 0.872772 1 Gln 4359 T A Pathogenic 0.658355 1 Gln 4359 T C Pathogenic 0.638881 1 Gln 4359 T G Pathogenic 0.658355 1 Gln 4358 C A Likely neutral 0.446355 1 Gln 4358 C G Likely neutral 0.446355 1 Gln 4358 C T Likely neutral 0.367528 0 Gln 4357 A C Likely neutral 0.428534 1 Gln 4357 A G Likely neutral 0.389805 1 Gln 4357 A T Neutral 0.359802 1 Gln 4356 G A Neutral 0.212878 0 Gln 4356 G C Neutral 0.273167 0 Gln 4356 G T Neutral 0.273167 0 Gln 4355 G A Likely pathogenic 0.56818 1 Gln 4355 G C Likely pathogenic 0.56818 1 Gln 4355 G T Likely pathogenic 0.56818 1 Gln 4354 G A Neutral 0.146553 0 Gln 4354 G C Neutral 0.283097 0 Gln 4354 G T Neutral 0.138066 0 Gln 4353 A C Neutral 0.302865 1 Gln 4353 A G Neutral 0.227617 0 Gln 4353 A T Neutral 0.221027 0 Gln 4352 T A Likely neutral 0.360093 1 Gln 4352 T C Likely neutral 0.326522 1 Gln 4352 T G Neutral 0.322339 1 Gln 4351 G A Neutral 0.24225 1 Gln 4351 G C Neutral 0.321074 1 Gln 4351 G T Neutral 0.321074 1 Gln 4350 G A Likely neutral 0.398935 1 Gln 4350 G C Likely neutral 0.451217 1 Gln 4350 G T Likely neutral 0.451217 1 Gln 4349 G A Pathogenic 0.90568 1 Gln 4349 G C Pathogenic 0.90568 1 Gln 4349 G T Pathogenic 0.90568 1 Gln 4348 T A Likely neutral 0.325217 1 Gln 4348 T C Likely neutral 0.325217 1 Gln 4348 T G Likely neutral 0.325217 1 Gln 4347 T A Likely neutral 0.375079 1 Gln 4347 T C Likely neutral 0.375079 1 Gln 4347 T G Likely neutral 0.375079 1 Gln 4346 C A Likely neutral 0.49481 1 Gln 4346 C G Likely neutral 0.49481 1 Gln 4346 C T Likely neutral 0.49481 1 Gln 4345 G A Neutral 0.162132 0 Gln 4345 G C Neutral 0.287654 0 Gln 4345 G T Neutral 0.287654 0 Gln 4344 A C Likely pathogenic 0.552 1 Gln 4344 A G Likely pathogenic 0.552 1 Gln 4344 A T Likely pathogenic 0.552 1 Gln 4343 T A Neutral 0.148507 0 Gln 4343 T C Neutral 0.106665 0 Gln 4343 T G Neutral 0.108026 0 Gln 4342 T A Neutral 0.133031 0 Gln 4342 T C Neutral 0.135742 0 Gln 4342 T G Neutral 0.127739 0 Gln 4341 C A Pathogenic 0.872772 1 Gln 4341 C G Pathogenic 0.872772 1 Gln 4341 C T Pathogenic 0.872772 1 Gln 4340 T A Neutral 0.374948 1 Gln 4340 T C Likely neutral 0.387653 0 Gln 4340 T G Neutral 0.374948 1 Gln 4339 C A Likely pathogenic 0.576449 1 Gln 4339 C G Likely pathogenic 0.576449 1 Gln 4339 C T Likely pathogenic 0.564982 1 Gln 4338 A C Likely neutral 0.437601 1 Gln 4338 A G Likely neutral 0.399184 1 Gln 4338 A T Likely neutral 0.410805 1 Gln 4337 T A Neutral 0.322522 0 Gln 4337 T C Neutral 0.293221 0 Gln 4337 T G Neutral 0.322522 1 Gln 4336 A C Neutral 0.210068 0 Gln 4336 A G Neutral 0.111472 0 Gln 4336 A T Neutral 0.108451 0 Gln 4335 G A Likely neutral 0.384636 0 Gln 4335 G C Likely neutral 0.47186 0 Gln 4335 G T Likely neutral 0.47186 0 Gln 4334 T A Likely neutral 0.471828 0 Gln 4334 T C Neutral 0.316177 1 Gln 4334 T G Likely neutral 0.471828 1 Gln 4333 C A Neutral 0.295669 1 Gln 4333 C G Neutral 0.295669 1 Gln 4333 C T Neutral 0.215974 0 Gln 4332 C A Pathogenic 0.736003 1 Gln 4332 C G Pathogenic 0.736003 1 Gln 4332 C T Pathogenic 0.703567 1 Gln 4331 T A Likely pathogenic 0.602417 1 Gln 4331 T C Likely pathogenic 0.584404 1 Gln 4331 T G Likely pathogenic 0.602417 1 Gln 4330 A C Likely pathogenic 0.540247 1 Gln 4330 A G Likely pathogenic 0.540247 1 Gln 4330 A T Likely pathogenic 0.540247 1 Gln 4329 G A Pathogenic 0.771757 1 Gln 4329 G C Pathogenic 0.771757 1 Gln 4329 G T Pathogenic 0.771757 1 Glu 14742 G A Likely pathogenic 0.58875 0 Glu 14742 G C Pathogenic 0.657225 0 Glu 14742 G T Pathogenic 0.657225 0 Glu 14741 T A Likely neutral 0.36524 1 Glu 14741 T C Neutral 0.291789 1 Glu 14741 T G Likely neutral 0.36524 1 Glu 14740 T A Likely pathogenic 0.50065 1 Glu 14740 T C Likely pathogenic 0.50065 1 Glu 14740 T G Likely pathogenic 0.50065 1 Glu 14739 C A Likely pathogenic 0.517058 1 Glu 14739 C G Likely pathogenic 0.517058 1 Glu 14739 C T Likely pathogenic 0.507731 0 Glu 14738 T A Likely pathogenic 0.53565 1 Glu 14738 T C Likely pathogenic 0.61789 0 Glu 14738 T G Likely pathogenic 0.53565 1 Glu 14737 T A Likely neutral 0.372165 1 Glu 14737 T C Likely neutral 0.356884 0 Glu 14737 T G Likely neutral 0.372165 1 Glu 14736 G A Likely neutral 0.404636 0 Glu 14736 G C Likely neutral 0.493167 1 Glu 14736 G T Likely neutral 0.493167 1 Glu 14735 T A Likely neutral 0.482597 1 Glu 14735 T C Likely neutral 0.482597 1 Glu 14735 T G Likely neutral 0.482597 1 Glu 14734 A C Likely neutral 0.468085 1 Glu 14734 A G Likely neutral 0.468085 1 Glu 14734 A T Likely neutral 0.468085 1 Glu 14733 G A Pathogenic 0.933834 1 Glu 14733 G C Pathogenic 0.933834 1 Glu 14733 G T Pathogenic 0.933834 1 Glu 14732 T A Likely pathogenic 0.520981 1 Glu 14732 T C Likely pathogenic 0.520981 1 Glu 14732 T G Likely pathogenic 0.520981 1 Glu 14731 T A Likely neutral 0.456958 1 Glu 14731 T C Likely neutral 0.456958 1 Glu 14731 T G Likely neutral 0.456958 1 Glu 14730 G A Pathogenic 0.917206 1 Glu 14730 G C Pathogenic 0.917206 1 Glu 14730 G T Pathogenic 0.917206 1 Glu 14729 A C Likely pathogenic 0.519081 1 Glu 14729 A G Likely pathogenic 0.519081 1 Glu 14729 A T Likely pathogenic 0.519081 1 Glu 14728 A C Likely pathogenic 0.575804 1 Glu 14728 A G Likely pathogenic 0.552782 0 Glu 14728 A T Likely pathogenic 0.575804 1 Glu 14727 A C Neutral 0.198696 0 Glu 14727 A G Neutral 0.1653 0 Glu 14727 A T Neutral 0.154769 0 Glu 14726 T A Neutral 0.338562 1 Glu 14726 T C Likely neutral 0.395961 1 Glu 14726 T G Likely neutral 0.402928 1 Glu 14725 A C Likely neutral 0.428031 1 Glu 14725 A G Likely neutral 0.428031 1 Glu 14725 A T Likely neutral 0.428031 1 Glu 14724 C A Pathogenic 0.80024 1 Glu 14724 C G Pathogenic 0.80024 1 Glu 14724 C T Pathogenic 0.80024 1 Glu 14723 A C Pathogenic 0.776137 1 Glu 14723 A G Pathogenic 0.776137 1 Glu 14723 A T Pathogenic 0.776137 1 Glu 14722 A C Likely pathogenic 0.663354 1 Glu 14722 A G Likely pathogenic 0.628087 1 Glu 14722 A T Likely pathogenic 0.663354 1 Glu 14721 C A Likely pathogenic 0.572326 1 Glu 14721 C G Likely pathogenic 0.572326 1 Glu 14721 C T Likely pathogenic 0.560639 1 Glu 14720 G A Likely pathogenic 0.528959 1 Glu 14720 G C Likely pathogenic 0.58676 1 Glu 14720 G T Likely pathogenic 0.58676 1 Glu 14719 A C Likely pathogenic 0.576476 1 Glu 14719 A G Likely pathogenic 0.59341 0 Glu 14719 A T Likely pathogenic 0.576476 1 Glu 14718 T A Neutral 0.181048 1 Glu 14718 T C Neutral 0.181048 1 Glu 14718 T G Neutral 0.181048 1 Glu 14717 G A Pathogenic 0.788893 1 Glu 14717 G C Pathogenic 0.788893 1 Glu 14717 G T Pathogenic 0.788893 1 Glu 14716 G A Neutral 0.170078 0 Glu 14716 G C Neutral 0.303175 0 Glu 14716 G T Neutral 0.199026 0 Glu 14715 T A Likely neutral 0.36524 1 Glu 14715 T C Neutral 0.291789 0 Glu 14715 T G Likely neutral 0.36524 1 Glu 14714 T A Likely pathogenic 0.527095 1 Glu 14714 T C Likely pathogenic 0.527095 1 Glu 14714 T G Likely pathogenic 0.527095 1 Glu 14713 T A Likely pathogenic 0.527095 1 Glu 14713 T C Likely pathogenic 0.527095 1 Glu 14713 T G Likely pathogenic 0.527095 1 Glu 14712 T A Likely pathogenic 0.527095 1 Glu 14712 T C Likely pathogenic 0.527095 1 Glu 14712 T G Likely pathogenic 0.527095 1 Glu 14711 T A Likely neutral 0.375079 1 Glu 14711 T C Likely neutral 0.375079 1 Glu 14711 T G Likely neutral 0.375079 1 Glu 14710 C A Pathogenic 0.794856 1 Glu 14710 C G Pathogenic 0.794856 1 Glu 14710 C T Pathogenic 0.794856 1 Glu 14709 A C Likely neutral 0.386234 0 Glu 14709 A G Likely neutral 0.368136 0 Glu 14709 A T Likely neutral 0.386234 0 Glu 14708 T A Likely neutral 0.461165 1 Glu 14708 T C Likely neutral 0.461165 1 Glu 14708 T G Likely neutral 0.47155 1 Glu 14707 A C Neutral 0.335286 1 Glu 14707 A G Neutral 0.279793 0 Glu 14707 A T Neutral 0.335286 1 Glu 14706 T A Neutral 0.356564 0 Glu 14706 T C Neutral 0.268998 0 Glu 14706 T G Neutral 0.356564 0 Glu 14705 C A Pathogenic 0.88991 1 Glu 14705 C G Pathogenic 0.88991 1 Glu 14705 C T Pathogenic 0.88991 1 Glu 14704 A C Likely pathogenic 0.602469 1 Glu 14704 A G Likely pathogenic 0.602469 1 Glu 14704 A T Likely pathogenic 0.602469 1 Glu 14703 T A Likely neutral 0.482806 1 Glu 14703 T C Likely neutral 0.396853 0 Glu 14703 T G Likely neutral 0.482806 1 Glu 14702 T A Neutral 0.342 1 Glu 14702 T C Likely neutral 0.394967 1 Glu 14702 T G Likely neutral 0.394967 1 Glu 14701 G A Neutral 0.126728 0 Glu 14701 G C Neutral 0.241249 0 Glu 14701 G T Neutral 0.241249 0 Glu 14700 G A Likely pathogenic 0.623657 1 Glu 14700 G C Pathogenic 0.679587 1 Glu 14700 G T Pathogenic 0.679587 1 Glu 14699 T A Likely pathogenic 0.605152 1 Glu 14699 T C Likely pathogenic 0.605152 1 Glu 14699 T G Likely pathogenic 0.605152 1 Glu 14698 C A Likely pathogenic 0.538036 1 Glu 14698 C G Likely pathogenic 0.538036 1 Glu 14698 C T Likely neutral 0.461668 1 Glu 14697 G A Neutral 0.151947 0 Glu 14697 G C Neutral 0.2312 0 Glu 14697 G T Neutral 0.151825 0 Glu 14696 T A Likely neutral 0.352843 1 Glu 14696 T C Neutral 0.255691 0 Glu 14696 T G Likely neutral 0.352843 1 Glu 14695 G A Likely neutral 0.389329 1 Glu 14695 G C Likely neutral 0.470153 1 Glu 14695 G T Likely neutral 0.470153 1 Glu 14694 G A Pathogenic 0.90568 1 Glu 14694 G C Pathogenic 0.90568 1 Glu 14694 G T Pathogenic 0.90568 1 Glu 14693 T A Neutral 0.215802 1 Glu 14693 T C Neutral 0.215802 1 Glu 14693 T G Neutral 0.215802 1 Glu 14692 T A Likely neutral 0.285961 0 Glu 14692 T C Neutral 0.154611 0 Glu 14692 T G Likely neutral 0.285961 0 Glu 14691 G A Neutral 0.186823 0 Glu 14691 G C Neutral 0.22843 0 Glu 14691 G T Neutral 0.176137 0 Glu 14690 T A Neutral 0.122544 0 Glu 14690 T C Neutral 0.149422 0 Glu 14690 T G Neutral 0.122544 0 Glu 14689 A C Likely neutral 0.379592 1 Glu 14689 A G Neutral 0.32569 0 Glu 14689 A T Likely neutral 0.379592 1 Glu 14688 G A Neutral 0.286118 0 Glu 14688 G C Neutral 0.311774 0 Glu 14688 G T Neutral 0.276696 0 Glu 14687 T A Likely neutral 0.474417 1 Glu 14687 T C Likely neutral 0.449109 1 Glu 14687 T G Likely neutral 0.354487 1 Glu 14686 C A Pathogenic 0.71995 1 Glu 14686 C G Pathogenic 0.71995 1 Glu 14686 C T Pathogenic 0.71995 1 Glu 14685 C A Likely neutral 0.393139 1 Glu 14685 C G Likely neutral 0.393139 1 Glu 14685 C T Neutral 0.337324 1 Glu 14684 G A Likely neutral 0.395289 0 Glu 14684 G C Likely neutral 0.380359 0 Glu 14684 G T Likely neutral 0.380359 0 Glu 14683 T A Likely neutral 0.438188 0 Glu 14683 T C Likely neutral 0.438188 0 Glu 14683 T G Likely neutral 0.438188 0 Glu 14682 G A Likely neutral 0.454641 1 Glu 14682 G C Likely pathogenic 0.557118 1 Glu 14682 G T Likely pathogenic 0.557118 1 Glu 14681 C A Neutral 0.306608 1 Glu 14681 C G Neutral 0.306608 1 Glu 14681 C T Neutral 0.283227 0 Glu 14680 G A Neutral 0.198 0 Glu 14680 G C Neutral 0.307457 0 Glu 14680 G T Neutral 0.307457 0 Glu 14679 A C Neutral 0.292179 1 Glu 14679 A G Neutral 0.196211 0 Glu 14679 A T Neutral 0.292179 1 Glu 14678 G A Likely pathogenic 0.513404 1 Glu 14678 G C Likely pathogenic 0.580907 1 Glu 14678 G T Likely pathogenic 0.580907 1 Glu 14677 A C Likely neutral 0.468168 1 Glu 14677 A G Likely neutral 0.468168 1 Glu 14677 A T Likely neutral 0.468168 1 Glu 14676 A C Pathogenic 0.639455 1 Glu 14676 A G Likely pathogenic 0.529556 1 Glu 14676 A T Pathogenic 0.639455 1 Glu 14675 T A Neutral 0.310083 0 Glu 14675 T C Neutral 0.24537 0 Glu 14675 T G Neutral 0.310083 0 Glu 14674 A C Neutral 0.214072 0 Glu 14674 A G Neutral 0.094179 0 Glu 14674 A T Neutral 0.088535 0 Gly 9991 A C Likely neutral 0.434744 1 Gly 9991 A G Neutral 0.353317 1 Gly 9991 A T Likely neutral 0.434744 1 Gly 9992 C A Likely pathogenic 0.551776 1 Gly 9992 C G Likely pathogenic 0.551776 1 Gly 9992 C T Likely pathogenic 0.53962 1 Gly 9993 T A Pathogenic 0.680088 1 Gly 9993 T C Pathogenic 0.680088 0 Gly 9993 T G Pathogenic 0.680088 1 Gly 9994 C A Pathogenic 0.700258 1 Gly 9994 C G Pathogenic 0.700258 1 Gly 9994 C T Pathogenic 0.692418 1 Gly 9995 T A Neutral 0.361244 1 Gly 9995 T C Likely neutral 0.363815 1 Gly 9995 T G Neutral 0.361244 1 Gly 9996 T A Neutral 0.350813 1 Gly 9996 T C Neutral 0.25789 1 Gly 9996 T G Neutral 0.350813 1 Gly 9997 T A Pathogenic 0.681074 1 Gly 9997 T C Likely pathogenic 0.616584 1 Gly 9997 T G Pathogenic 0.681074 1 Gly 9998 T A Likely pathogenic 0.537284 1 Gly 9998 T C Likely pathogenic 0.511333 1 Gly 9998 T G Likely pathogenic 0.537284 1 Gly 9999 A C Likely neutral 0.468085 1 Gly 9999 A G Likely neutral 0.468085 1 Gly 9999 A T Likely neutral 0.468085 1 Gly 10000 G A Pathogenic 0.933834 1 Gly 10000 G C Pathogenic 0.933834 1 Gly 10000 G T Pathogenic 0.933834 1 Gly 10001 T A Likely pathogenic 0.561343 1 Gly 10001 T C Likely pathogenic 0.561343 1 Gly 10001 T G Likely pathogenic 0.561343 1 Gly 10002 A C Pathogenic 0.78682 1 Gly 10002 A G Pathogenic 0.78682 1 Gly 10002 A T Pathogenic 0.78682 1 Gly 10003 T A Likely pathogenic 0.526879 1 Gly 10003 T C Likely pathogenic 0.55082 0 Gly 10003 T G Likely pathogenic 0.526879 1 Gly 10004 A C Neutral 0.097079 1 Gly 10004 A G Neutral 0.218798 1 Gly 10004 A T Neutral 0.103234 1 Gly 10005 A C Likely neutral 0.485443 1 Gly 10005 A G Likely neutral 0.402262 1 Gly 10005 A T Likely neutral 0.485443 1 Gly 10006 A C Neutral 0.156748 0 Gly 10006 A G Neutral 0.145384 0 Gly 10006 A T Neutral 0.147455 0 Gly 10007 T A Neutral 0.144564 0 Gly 10007 T C Neutral 0.12769 0 Gly 10007 T G Neutral 0.234224 0 Gly 10008 A C Likely neutral 0.432846 1 Gly 10008 A G Likely neutral 0.432846 1 Gly 10008 A T Likely neutral 0.432846 1 Gly 10009 G A Likely pathogenic 0.628799 0 Gly 10009 G C Pathogenic 0.67108 1 Gly 10009 G T Pathogenic 0.67108 1 Gly 10010 T A Likely pathogenic 0.623925 1 Gly 10010 T C Likely pathogenic 0.623925 1 Gly 10010 T G Likely pathogenic 0.623925 1 Gly 10011 A C Likely neutral 0.482315 1 Gly 10011 A G Likely neutral 0.482315 1 Gly 10011 A T Likely neutral 0.482315 1 Gly 10012 C A Likely neutral 0.416491 1 Gly 10012 C G Likely neutral 0.416491 1 Gly 10012 C T Neutral 0.301549 1 Gly 10013 C A Neutral 0.11862 0 Gly 10013 C G Neutral 0.126953 0 Gly 10013 C T Neutral 0.113854 0 Gly 10014 G A Neutral 0.141225 0 Gly 10014 G C Neutral 0.262145 1 Gly 10014 G T Neutral 0.143558 1 Gly 10015 T A Neutral 0.196193 0 Gly 10015 T C Neutral 0.18781 0 Gly 10015 T G Neutral 0.196193 1 Gly 10016 T A Pathogenic 0.775779 1 Gly 10016 T C Pathogenic 0.775779 1 Gly 10016 T G Pathogenic 0.775779 1 Gly 10017 A C Likely neutral 0.458047 1 Gly 10017 A G Likely neutral 0.46836 0 Gly 10017 A T Likely neutral 0.458047 1 Gly 10018 A C Likely pathogenic 0.684357 1 Gly 10018 A G Likely pathogenic 0.684357 1 Gly 10018 A T Likely pathogenic 0.684357 1 Gly 10019 C A Likely pathogenic 0.560761 1 Gly 10019 C G Likely pathogenic 0.560761 1 Gly 10019 C T Likely pathogenic 0.560761 1 Gly 10020 T A Likely neutral 0.343502 1 Gly 10020 T C Likely neutral 0.343502 1 Gly 10020 T G Likely neutral 0.343502 1 Gly 10021 T A Likely neutral 0.375079 1 Gly 10021 T C Likely neutral 0.375079 1 Gly 10021 T G Likely neutral 0.375079 1 Gly 10022 C A Likely pathogenic 0.540601 1 Gly 10022 C G Likely pathogenic 0.540601 1 Gly 10022 C T Likely pathogenic 0.540601 1 Gly 10023 C A Pathogenic 0.657095 1 Gly 10023 C G Pathogenic 0.657095 1 Gly 10023 C T Pathogenic 0.657095 1 Gly 10024 A C Likely pathogenic 0.612614 1 Gly 10024 A G Likely pathogenic 0.612614 1 Gly 10024 A T Likely pathogenic 0.612614 1 Gly 10025 A C Likely pathogenic 0.635665 1 Gly 10025 A G Likely pathogenic 0.635665 1 Gly 10025 A T Likely pathogenic 0.635665 1 Gly 10026 T A Pathogenic 0.638231 1 Gly 10026 T C Pathogenic 0.638231 1 Gly 10026 T G Pathogenic 0.638231 1 Gly 10027 T A Neutral 0.32557 1 Gly 10027 T C Neutral 0.235976 0 Gly 10027 T G Neutral 0.32557 1 Gly 10028 A C Pathogenic 0.777675 1 Gly 10028 A G Pathogenic 0.777675 1 Gly 10028 A T Pathogenic 0.777675 1 Gly 10029 A C Likely neutral 0.34311 1 Gly 10029 A G Neutral 0.199574 0 Gly 10029 A T Neutral 0.256812 0 Gly 10030 C A Likely neutral 0.376541 1 Gly 10030 C G Likely neutral 0.415612 1 Gly 10030 C T Likely neutral 0.386632 0 Gly 10031 T A Neutral 0.145828 0 Gly 10031 T C Neutral 0.141871 0 Gly 10031 T G Neutral 0.227533 0 Gly 10032 A C Likely neutral 0.375979 0 Gly 10032 A G Neutral 0.298679 0 Gly 10032 A T Likely neutral 0.375979 0 Gly 10033 G A Likely pathogenic 0.607502 1 Gly 10033 G C Pathogenic 0.672266 1 Gly 10033 G T Pathogenic 0.672266 1 Gly 10034 T A Neutral 0.087842 0 Gly 10034 T C Neutral 0.097321 0 Gly 10034 T G Neutral 0.159598 0 Gly 10035 T A Likely pathogenic 0.510841 1 Gly 10035 T C Likely neutral 0.378166 1 Gly 10035 T G Likely pathogenic 0.510841 1 Gly 10036 T A Neutral 0.347434 1 Gly 10036 T C Likely neutral 0.287245 1 Gly 10036 T G Neutral 0.347434 1 Gly 10037 T A Neutral 0.190023 1 Gly 10037 T C Neutral 0.135074 1 Gly 10037 T G Neutral 0.237467 1 Gly 10038 G A Likely pathogenic 0.59857 1 Gly 10038 G C Pathogenic 0.68185 1 Gly 10038 G T Pathogenic 0.68185 1 Gly 10039 A C Neutral 0.286307 1 Gly 10039 A G Neutral 0.139183 1 Gly 10039 A T Neutral 0.286307 1 Gly 10040 C A Neutral 0.15662 0 Gly 10040 C G Neutral 0.231407 0 Gly 10040 C T Neutral 0.168017 0 Gly 10041 A C Neutral 0.079114 0 Gly 10041 A G Neutral 0.102302 0 Gly 10041 A T Neutral 0.074706 0 Gly 10042 A C Neutral 0.108719 1 Gly 10042 A G Neutral 0.182632 0 Gly 10042 A T Neutral 0.146199 1 Gly 10043 C A Neutral 0.195813 0 Gly 10043 C G Neutral 0.294124 0 Gly 10043 C T Neutral 0.167219 0 Gly 10044 A C Neutral 0.211472 0 Gly 10044 A G Neutral 0.211472 0 Gly 10044 A T Neutral 0.234736 0 Gly 10045 T A Neutral 0.143599 0 Gly 10045 T C Neutral 0.119185 0 Gly 10045 T G Neutral 0.121246 0 Gly 10046 T A Neutral 0.305006 1 Gly 10046 T C Neutral 0.242635 1 Gly 10046 T G Neutral 0.305006 1 Gly 10047 C A Likely pathogenic 0.529521 1 Gly 10047 C G Likely neutral 0.491372 1 Gly 10047 C T Likely neutral 0.448078 1 Gly 10048 A C Neutral 0.296251 1 Gly 10048 A G Neutral 0.211964 1 Gly 10048 A T Neutral 0.237466 1 Gly 10049 A C Likely neutral 0.40123 1 Gly 10049 A G Likely neutral 0.368168 1 Gly 10049 A T Likely neutral 0.349318 1 Gly 10050 A C Likely pathogenic 0.53211 1 Gly 10050 A G Likely neutral 0.416399 1 Gly 10050 A T Likely pathogenic 0.53211 1 Gly 10051 A C Likely pathogenic 0.650529 1 Gly 10051 A G Likely pathogenic 0.567912 1 Gly 10051 A T Likely pathogenic 0.650529 1 Gly 10052 A C Likely neutral 0.384969 1 Gly 10052 A G Likely neutral 0.304245 1 Gly 10052 A T Neutral 0.302748 1 Gly 10053 A C Neutral 0.349763 1 Gly 10053 A G Neutral 0.303397 1 Gly 10053 A T Neutral 0.349763 1 Gly 10054 G A Pathogenic 0.729676 1 Gly 10054 G C Pathogenic 0.747744 1 Gly 10054 G T Pathogenic 0.747744 1 Gly 10055 A C Likely neutral 0.413629 1 Gly 10055 A G Likely neutral 0.339604 0 Gly 10055 A T Likely neutral 0.339604 1 Gly 10056 G A Likely pathogenic 0.55689 1 Gly 10056 G C Likely pathogenic 0.618902 1 Gly 10056 G T Likely pathogenic 0.618902 1 Gly 10057 T A Likely neutral 0.460387 1 Gly 10057 T C Likely neutral 0.433497 1 Gly 10057 T G Likely neutral 0.47727 1 Gly 10058 A C Likely neutral 0.477818 1 Gly 10058 A G Likely neutral 0.446616 1 Gly 10058 A T Likely neutral 0.477818 1 His 12138 G A Pathogenic 0.899313 1 His 12138 G C Pathogenic 0.899313 1 His 12138 G T Pathogenic 0.899313 1 His 12139 T A Likely pathogenic 0.561343 1 His 12139 T C Likely pathogenic 0.561343 1 His 12139 T G Likely pathogenic 0.561343 1 His 12140 A C Likely neutral 0.491711 1 His 12140 A G Likely neutral 0.405914 1 His 12140 A T Likely pathogenic 0.520469 1 His 12141 A C Likely neutral 0.478097 1 His 12141 A G Likely neutral 0.413207 1 His 12141 A T Likely neutral 0.478097 0 His 12142 A C Likely pathogenic 0.599573 1 His 12142 A G Pathogenic 0.633078 1 His 12142 A T Likely pathogenic 0.56534 1 His 12143 T A Likely pathogenic 0.526134 1 His 12143 T C Likely neutral 0.465269 1 His 12143 T G Likely pathogenic 0.526134 1 His 12144 A C Pathogenic 0.78682 1 His 12144 A G Pathogenic 0.78682 1 His 12144 A T Pathogenic 0.78682 1 His 12145 T A Likely neutral 0.432439 1 His 12145 T C Likely neutral 0.432439 1 His 12145 T G Likely neutral 0.432439 1 His 12146 A C Likely neutral 0.468085 1 His 12146 A G Likely neutral 0.468085 1 His 12146 A T Likely neutral 0.468085 1 His 12147 G A Pathogenic 0.875726 1 His 12147 G C Pathogenic 0.89777 1 His 12147 G T Pathogenic 0.89777 1 His 12148 T A Likely pathogenic 0.520981 1 His 12148 T C Likely pathogenic 0.520981 1 His 12148 T G Likely pathogenic 0.520981 1 His 12149 T A Pathogenic 0.771386 1 His 12149 T C Pathogenic 0.771386 1 His 12149 T G Pathogenic 0.771386 1 His 12150 T A Pathogenic 0.775779 1 His 12150 T C Pathogenic 0.775779 1 His 12150 T G Pathogenic 0.775779 1 His 12151 A C Likely pathogenic 0.649738 1 His 12151 A G Likely pathogenic 0.649738 1 His 12151 A T Likely pathogenic 0.649738 1 His 12152 A C Neutral 0.148422 1 His 12152 A G Neutral 0.217491 1 His 12152 A T Neutral 0.217491 1 His 12153 C A Neutral 0.111539 0 His 12153 C G Neutral 0.210179 0 His 12153 C T Neutral 0.090172 0 His 12154 C A Neutral 0.133819 0 His 12154 C G Neutral 0.276653 0 His 12154 C T Neutral 0.122468 0 His 12155 A C Likely pathogenic 0.612614 1 His 12155 A G Likely pathogenic 0.612614 1 His 12155 A T Likely pathogenic 0.612614 1 His 12156 A C Pathogenic 0.73642 1 His 12156 A G Pathogenic 0.73642 1 His 12156 A T Pathogenic 0.73642 1 His 12157 A C Pathogenic 0.73642 1 His 12157 A G Pathogenic 0.73642 1 His 12157 A T Pathogenic 0.73642 1 His 12158 A C Likely pathogenic 0.684357 1 His 12158 A G Likely pathogenic 0.684357 1 His 12158 A T Likely pathogenic 0.684357 1 His 12159 C A Pathogenic 0.650833 1 His 12159 C G Pathogenic 0.650833 1 His 12159 C T Likely pathogenic 0.550419 1 His 12160 A C Likely neutral 0.436136 1 His 12160 A G Likely neutral 0.413631 1 His 12160 A T Likely neutral 0.436136 1 His 12161 T A Likely neutral 0.434532 1 His 12161 T C Likely neutral 0.383652 1 His 12161 T G Likely neutral 0.434532 1 His 12162 C A Likely pathogenic 0.576449 1 His 12162 C G Likely pathogenic 0.576449 1 His 12162 C T Likely pathogenic 0.564982 1 His 12163 A C Pathogenic 0.699696 1 His 12163 A G Pathogenic 0.699696 1 His 12163 A T Pathogenic 0.699696 1 His 12164 G A Pathogenic 0.80484 1 His 12164 G C Pathogenic 0.841648 1 His 12164 G T Pathogenic 0.841648 1 His 12165 A C Pathogenic 0.677382 1 His 12165 A G Likely pathogenic 0.640748 1 His 12165 A T Pathogenic 0.677382 1 His 12166 T A Neutral 0.267399 1 His 12166 T C Neutral 0.222731 1 His 12166 T G Neutral 0.267399 1 His 12167 T A Neutral 0.317432 1 His 12167 T C Neutral 0.292013 1 His 12167 T G Neutral 0.317432 1 His 12168 G A Pathogenic 0.71321 1 His 12168 G C Pathogenic 0.71321 1 His 12168 G T Pathogenic 0.71321 1 His 12169 T A Likely neutral 0.350222 1 His 12169 T C Likely neutral 0.350222 1 His 12169 T G Likely neutral 0.350222 1 His 12170 G A Pathogenic 0.765256 1 His 12170 G C Pathogenic 0.765256 1 His 12170 G T Pathogenic 0.765256 1 His 12171 A C Likely neutral 0.424786 1 His 12171 A G Likely neutral 0.424786 1 His 12171 A T Likely neutral 0.424786 1 His 12172 A C Likely pathogenic 0.56836 1 His 12172 A G Likely pathogenic 0.526207 1 His 12172 A T Likely pathogenic 0.56836 1 His 12173 T A Likely pathogenic 0.510741 1 His 12173 T C Likely neutral 0.471212 1 His 12173 T G Likely pathogenic 0.510741 1 His 12174 C A Pathogenic 0.872772 1 His 12174 C G Pathogenic 0.872772 1 His 12174 C T Pathogenic 0.872772 1 His 12175 T A Likely pathogenic 0.58736 1 His 12175 T C Likely pathogenic 0.574147 1 His 12175 T G Likely pathogenic 0.58736 1 His 12176 G A Likely neutral 0.367926 1 His 12176 G C Likely neutral 0.434539 1 His 12176 G T Likely neutral 0.389942 1 His 12177 A C Likely pathogenic 0.506969 1 His 12177 A G Neutral 0.360043 1 His 12177 A T Likely pathogenic 0.506969 1 His 12178 C A Neutral 0.161575 0 His 12178 C G Neutral 0.266135 0 His 12178 C T Neutral 0.170554 0 His 12179 A C Neutral 0.18393 0 His 12179 A G Neutral 0.233432 0 His 12179 A T Neutral 0.206493 0 His 12180 A C Likely pathogenic 0.591227 1 His 12180 A G Likely pathogenic 0.591227 1 His 12180 A T Likely pathogenic 0.525782 1 His 12181 C A Neutral 0.363706 0 His 12181 C G Neutral 0.363706 0 His 12181 C T Neutral 0.320151 0 His 12182 A C Pathogenic 0.699696 1 His 12182 A G Pathogenic 0.699696 1 His 12182 A T Pathogenic 0.699696 1 His 12183 G A Pathogenic 0.801564 1 His 12183 G C Pathogenic 0.838788 1 His 12183 G T Pathogenic 0.838788 1 His 12184 A C Neutral 0.305105 0 His 12184 A G Neutral 0.238995 0 His 12184 A T Neutral 0.305105 0 His 12185 G A Neutral 0.295204 1 His 12185 G C Neutral 0.304003 1 His 12185 G T Neutral 0.304003 1 His 12186 G A Neutral 0.113839 0 His 12186 G C Neutral 0.158399 0 His 12186 G T Neutral 0.192845 1 His 12187 C A Neutral 0.152681 0 His 12187 C G Neutral 0.24888 0 His 12187 C T Neutral 0.152465 0 His 12188 T A Neutral 0.215361 0 His 12188 T C Neutral 0.13086 0 His 12188 T G Neutral 0.215361 0 His 12189 T A Neutral 0.242958 0 His 12189 T C Neutral 0.116402 0 His 12189 T G Neutral 0.242958 0 His 12190 A C Neutral 0.118213 1 His 12190 A G Neutral 0.098257 1 His 12190 A T Neutral 0.148299 1 His 12191 C A Neutral 0.094681 0 His 12191 C G Neutral 0.182861 0 His 12191 C T Neutral 0.114509 0 His 12192 G A Neutral 0.121872 0 His 12192 G C Neutral 0.117493 0 His 12192 G T Neutral 0.159307 0 His 12193 A C Neutral 0.108366 0 His 12193 A G Neutral 0.19914 0 His 12193 A T Neutral 0.130359 0 His 12194 C A Likely neutral 0.39477 1 His 12194 C G Likely neutral 0.431575 1 His 12194 C T Neutral 0.336825 0 His 12195 C A Neutral 0.305584 1 His 12195 C G Neutral 0.305584 1 His 12195 C T Neutral 0.256985 1 His 12196 C A Neutral 0.217013 0 His 12196 C G Neutral 0.217013 0 His 12196 C T Neutral 0.183691 0 His 12197 C A Pathogenic 0.696834 1 His 12197 C G Pathogenic 0.696834 1 His 12197 C T Likely pathogenic 0.617531 1 His 12198 T A Likely pathogenic 0.528246 1 His 12198 T C Likely pathogenic 0.528246 1 His 12198 T G Likely pathogenic 0.528246 1 His 12199 T A Pathogenic 0.775779 1 His 12199 T C Pathogenic 0.775779 1 His 12199 T G Pathogenic 0.775779 1 His 12200 A C Likely pathogenic 0.512749 1 His 12200 A G Likely neutral 0.404472 1 His 12200 A T Likely pathogenic 0.512749 1 His 12201 T A Likely neutral 0.433095 1 His 12201 T C Likely neutral 0.462684 1 His 12201 T G Likely neutral 0.476622 1 His 12202 T A Likely pathogenic 0.529277 0 His 12202 T C Likely neutral 0.435821 1 His 12202 T G Likely pathogenic 0.529277 1 His 12203 T A Likely pathogenic 0.516454 1 His 12203 T C Likely neutral 0.379239 1 His 12203 T G Likely pathogenic 0.516454 1 His 12204 A C Likely neutral 0.482315 1 His 12204 A G Likely neutral 0.482315 1 His 12204 A T Likely neutral 0.482315 1 His 12205 C A Pathogenic 0.674612 1 His 12205 C G Pathogenic 0.674612 1 His 12205 C T Pathogenic 0.674612 1 His 12206 C A Likely neutral 0.435195 1 His 12206 C G Likely neutral 0.435195 1 His 12206 C T Likely neutral 0.435195 1 Ile 4263 A C Likely neutral 0.398614 1 Ile 4263 A G Likely neutral 0.398614 1 Ile 4263 A T Likely neutral 0.398614 1 Ile 4264 G A Pathogenic 0.922413 1 Ile 4264 G C Pathogenic 0.922413 1 Ile 4264 G T Pathogenic 0.922413 1 Ile 4265 A C Likely pathogenic 0.547549 1 Ile 4265 A G Likely pathogenic 0.547549 1 Ile 4265 A T Likely pathogenic 0.547549 1 Ile 4266 A C Pathogenic 0.827889 1 Ile 4266 A G Pathogenic 0.827889 1 Ile 4266 A T Pathogenic 0.827889 1 Ile 4267 A C Pathogenic 0.883127 1 Ile 4267 A G Pathogenic 0.883127 1 Ile 4267 A T Pathogenic 0.883127 1 Ile 4268 T A Likely pathogenic 0.655077 1 Ile 4268 T C Likely pathogenic 0.67617 1 Ile 4268 T G Likely pathogenic 0.655077 1 Ile 4269 A C Pathogenic 0.851567 1 Ile 4269 A G Pathogenic 0.851567 1 Ile 4269 A T Pathogenic 0.851567 1 Ile 4270 T A Neutral 0.326081 1 Ile 4270 T C Neutral 0.354232 1 Ile 4270 T G Neutral 0.326081 1 Ile 4271 G A Pathogenic 0.766949 1 Ile 4271 G C Pathogenic 0.766949 1 Ile 4271 G T Pathogenic 0.766949 1 Ile 4272 T A Pathogenic 0.776058 1 Ile 4272 T C Pathogenic 0.776058 1 Ile 4272 T G Pathogenic 0.776058 1 Ile 4273 C A Pathogenic 0.87982 1 Ile 4273 C G Pathogenic 0.87982 1 Ile 4273 C T Pathogenic 0.87982 1 Ile 4274 T A Likely pathogenic 0.646768 1 Ile 4274 T C Likely pathogenic 0.653443 1 Ile 4274 T G Likely pathogenic 0.646768 1 Ile 4275 G A Pathogenic 0.785592 1 Ile 4275 G C Pathogenic 0.785592 1 Ile 4275 G T Pathogenic 0.785592 1 Ile 4276 A C Pathogenic 0.681711 1 Ile 4276 A G Pathogenic 0.681711 1 Ile 4276 A T Pathogenic 0.681711 1 Ile 4277 T A Neutral 0.232384 0 Ile 4277 T C Neutral 0.153285 0 Ile 4277 T G Neutral 0.232384 0 Ile 4278 A C Likely pathogenic 0.667244 1 Ile 4278 A G Likely pathogenic 0.616235 1 Ile 4278 A T Likely pathogenic 0.667244 1 Ile 4279 A C Pathogenic 0.69395 1 Ile 4279 A G Pathogenic 0.69395 1 Ile 4279 A T Pathogenic 0.69395 1 Ile 4280 A C Likely pathogenic 0.51315 1 Ile 4280 A G Likely pathogenic 0.530133 1 Ile 4280 A T Likely pathogenic 0.530133 1 Ile 4281 A C Likely pathogenic 0.552649 1 Ile 4281 A G Likely pathogenic 0.552649 1 Ile 4281 A T Likely pathogenic 0.552649 1 Ile 4282 G A Pathogenic 0.922413 1 Ile 4282 G C Pathogenic 0.922413 1 Ile 4282 G T Pathogenic 0.922413 1 Ile 4283 A C Pathogenic 0.682441 1 Ile 4283 A G Pathogenic 0.682441 1 Ile 4283 A T Pathogenic 0.682441 1 Ile 4284 G A Likely pathogenic 0.595079 0 Ile 4284 G C Likely pathogenic 0.606153 0 Ile 4284 G T Likely pathogenic 0.606153 0 Ile 4285 T A Likely pathogenic 0.561141 1 Ile 4285 T C Likely pathogenic 0.561141 1 Ile 4285 T G Likely pathogenic 0.561141 1 Ile 4286 T A Pathogenic 0.829214 1 Ile 4286 T C Pathogenic 0.829214 1 Ile 4286 T G Pathogenic 0.829214 1 Ile 4287 A C Likely pathogenic 0.545183 1 Ile 4287 A G Likely pathogenic 0.545183 1 Ile 4287 A T Likely pathogenic 0.545183 1 Ile 4288 C A Pathogenic 0.781012 1 Ile 4288 C G Pathogenic 0.781012 1 Ile 4288 C T Pathogenic 0.781012 1 Ile 4289 T A Likely pathogenic 0.557289 1 Ile 4289 T C Likely pathogenic 0.557289 1 Ile 4289 T G Likely pathogenic 0.557289 1 Ile 4290 T A Likely pathogenic 0.576718 1 Ile 4290 T C Likely pathogenic 0.576718 1 Ile 4290 T G Likely pathogenic 0.576718 1 Ile 4291 T A Likely neutral 0.342678 1 Ile 4291 T C Likely neutral 0.342678 1 Ile 4291 T G Likely neutral 0.342678 1 Ile 4292 G A Pathogenic 0.809824 1 Ile 4292 G C Pathogenic 0.809824 1 Ile 4292 G T Pathogenic 0.809824 1 Ile 4293 A C Likely pathogenic 0.617732 1 Ile 4293 A G Likely pathogenic 0.617732 1 Ile 4293 A T Likely pathogenic 0.617732 1 Ile 4294 T A Likely pathogenic 0.548361 1 Ile 4294 T C Likely pathogenic 0.548361 1 Ile 4294 T G Likely pathogenic 0.548361 1 Ile 4295 A C Likely neutral 0.427032 1 Ile 4295 A G Likely neutral 0.364541 1 Ile 4295 A T Likely neutral 0.427032 1 Ile 4296 G A Pathogenic 0.827301 1 Ile 4296 G C Pathogenic 0.827301 1 Ile 4296 G T Pathogenic 0.827301 1 Ile 4297 A C Pathogenic 0.682441 1 Ile 4297 A G Pathogenic 0.682441 1 Ile 4297 A T Pathogenic 0.682441 1 Ile 4298 G A Pathogenic 0.952477 1 Ile 4298 G C Pathogenic 0.952477 1 Ile 4298 G T Pathogenic 0.952477 1 Ile 4299 T A Likely pathogenic 0.619131 1 Ile 4299 T C Likely pathogenic 0.619131 1 Ile 4299 T G Likely pathogenic 0.619131 1 Ile 4300 A C Pathogenic 0.807423 1 Ile 4300 A G Pathogenic 0.777312 1 Ile 4300 A T Pathogenic 0.807423 1 Ile 4301 A C Pathogenic 0.827889 1 Ile 4301 A G Pathogenic 0.827889 1 Ile 4301 A T Pathogenic 0.827889 1 Ile 4302 A C Pathogenic 0.706664 1 Ile 4302 A G Pathogenic 0.706664 1 Ile 4302 A T Pathogenic 0.706664 1 Ile 4303 T A Neutral 0.207677 0 Ile 4303 T C Neutral 0.207677 0 Ile 4303 T G Neutral 0.25589 0 Ile 4304 A C Neutral 0.101 1 Ile 4304 A G Neutral 0.135436 1 Ile 4304 A T Neutral 0.094128 1 Ile 4305 A C Pathogenic 0.732725 1 Ile 4305 A G Pathogenic 0.732725 1 Ile 4305 A T Pathogenic 0.732725 1 Ile 4306 T A Likely pathogenic 0.555408 1 Ile 4306 T C Likely pathogenic 0.555408 1 Ile 4306 T G Likely pathogenic 0.555408 1 Ile 4307 A C Likely pathogenic 0.597953 1 Ile 4307 A G Likely pathogenic 0.597953 1 Ile 4307 A T Likely pathogenic 0.597953 1 Ile 4308 G A Likely pathogenic 0.659084 1 Ile 4308 G C Likely pathogenic 0.659084 1 Ile 4308 G T Likely pathogenic 0.659084 1 Ile 4309 G A Likely pathogenic 0.553385 0 Ile 4309 G C Likely neutral 0.489266 1 Ile 4309 G T Likely neutral 0.489266 1 Ile 4310 A C Neutral 0.28436 1 Ile 4310 A G Neutral 0.324918 0 Ile 4310 A T Neutral 0.28436 1 Ile 4311 G A Pathogenic 0.916975 1 Ile 4311 G C Pathogenic 0.916975 1 Ile 4311 G T Pathogenic 0.916975 1 Ile 4312 C A Neutral 0.155589 0 Ile 4312 C G Neutral 0.243001 0 Ile 4312 C T Neutral 0.177567 0 Ile 4313 T A Neutral 0.21057 0 Ile 4313 T C Neutral 0.177008 0 Ile 4313 T G Neutral 0.161774 0 Ile 4314 T A Neutral 0.194939 0 Ile 4314 T C Neutral 0.121051 0 Ile 4314 T G Neutral 0.248613 0 Ile 4315 A C Neutral 0.135548 0 Ile 4315 A G Neutral 0.19565 0 Ile 4315 A T Neutral 0.140842 0 Ile 4316 A C Pathogenic 0.69395 1 Ile 4316 A G Pathogenic 0.69395 1 Ile 4316 A T Pathogenic 0.69395 1 Ile 4317 A C Likely neutral 0.421841 1 Ile 4317 A G Neutral 0.24575 1 Ile 4317 A T Likely neutral 0.421841 1 Ile 4318 C A Neutral 0.210417 0 Ile 4318 C G Neutral 0.144574 0 Ile 4318 C T Neutral 0.130055 0 Ile 4319 C A Likely pathogenic 0.598646 1 Ile 4319 C G Likely pathogenic 0.598646 1 Ile 4319 C T Likely pathogenic 0.598646 1 Ile 4320 C A Likely neutral 0.389061 1 Ile 4320 C G Likely neutral 0.389061 1 Ile 4320 C T Likely neutral 0.389061 1 Ile 4321 C A Neutral 0.315693 1 Ile 4321 C G Neutral 0.315693 1 Ile 4321 C T Neutral 0.273792 0 Ile 4322 C A Pathogenic 0.781319 1 Ile 4322 C G Pathogenic 0.781319 1 Ile 4322 C T Pathogenic 0.781319 1 Ile 4323 T A Likely pathogenic 0.557289 1 Ile 4323 T C Likely pathogenic 0.557289 1 Ile 4323 T G Likely pathogenic 0.557289 1 Ile 4324 T A Pathogenic 0.829214 1 Ile 4324 T C Pathogenic 0.829214 1 Ile 4324 T G Pathogenic 0.829214 1 Ile 4325 A C Likely pathogenic 0.609422 1 Ile 4325 A G Likely pathogenic 0.501448 1 Ile 4325 A T Likely pathogenic 0.609422 1 Ile 4326 T A Pathogenic 0.715167 1 Ile 4326 T C Pathogenic 0.715167 1 Ile 4326 T G Pathogenic 0.715167 1 Ile 4327 T A Pathogenic 0.79398 1 Ile 4327 T C Pathogenic 0.79398 1 Ile 4327 T G Pathogenic 0.79398 1 Ile 4328 T A Likely pathogenic 0.530851 1 Ile 4328 T C Likely pathogenic 0.530851 1 Ile 4328 T G Likely pathogenic 0.530851 1 Ile 4329 C A Pathogenic 0.87982 1 Ile 4329 C G Pathogenic 0.87982 1 Ile 4329 C T Pathogenic 0.87982 1 Ile 4330 T A Pathogenic 0.668027 1 Ile 4330 T C Pathogenic 0.668027 1 Ile 4330 T G Pathogenic 0.668027 1 Ile 4331 A C Likely neutral 0.386061 1 Ile 4331 A G Likely neutral 0.321902 1 Ile 4331 A T Likely neutral 0.386061 1 Leu(CUN) 12266 A C Likely pathogenic 0.520265 1 Leu(CUN) 12266 A G Likely neutral 0.360727 1 Leu(CUN) 12266 A T Likely pathogenic 0.520265 1 Leu(CUN) 12267 C A Pathogenic 0.754809 1 Leu(CUN) 12267 C G Pathogenic 0.754809 1 Leu(CUN) 12267 C T Pathogenic 0.754809 1 Leu(CUN) 12268 T A Likely pathogenic 0.528246 1 Leu(CUN) 12268 T C Likely pathogenic 0.528246 1 Leu(CUN) 12268 T G Likely pathogenic 0.528246 1 Leu(CUN) 12269 T A Pathogenic 0.771386 1 Leu(CUN) 12269 T C Pathogenic 0.771386 1 Leu(CUN) 12269 T G Pathogenic 0.771386 1 Leu(CUN) 12270 T A Pathogenic 0.771386 1 Leu(CUN) 12270 T C Pathogenic 0.771386 1 Leu(CUN) 12270 T G Pathogenic 0.771386 1 Leu(CUN) 12271 T A Pathogenic 0.666281 1 Leu(CUN) 12271 T C Likely pathogenic 0.592569 1 Leu(CUN) 12271 T G Pathogenic 0.666281 1 Leu(CUN) 12272 A C Pathogenic 0.777675 1 Leu(CUN) 12272 A G Pathogenic 0.777675 1 Leu(CUN) 12272 A T Pathogenic 0.777675 1 Leu(CUN) 12273 A C Neutral 0.21889 1 Leu(CUN) 12273 A G Neutral 0.281684 1 Leu(CUN) 12273 A T Neutral 0.183972 1 Leu(CUN) 12274 A C Likely neutral 0.444728 1 Leu(CUN) 12274 A G Likely neutral 0.444728 1 Leu(CUN) 12274 A T Likely neutral 0.444728 1 Leu(CUN) 12275 G A Likely pathogenic 0.63813 1 Leu(CUN) 12275 G C Likely pathogenic 0.63813 1 Leu(CUN) 12275 G T Likely pathogenic 0.63813 1 Leu(CUN) 12276 G A Pathogenic 0.755929 1 Leu(CUN) 12276 G C Pathogenic 0.755929 1 Leu(CUN) 12276 G T Pathogenic 0.755929 1 Leu(CUN) 12277 A C Pathogenic 0.718727 1 Leu(CUN) 12277 A G Pathogenic 0.718727 1 Leu(CUN) 12277 A T Pathogenic 0.718727 1 Leu(CUN) 12278 T A Likely pathogenic 0.582519 1 Leu(CUN) 12278 T C Likely pathogenic 0.582519 1 Leu(CUN) 12278 T G Likely pathogenic 0.582519 1 Leu(CUN) 12279 A C Likely neutral 0.450436 1 Leu(CUN) 12279 A G Likely neutral 0.366602 1 Leu(CUN) 12279 A T Likely neutral 0.450436 1 Leu(CUN) 12280 A C Likely neutral 0.340492 0 Leu(CUN) 12280 A G Neutral 0.193991 0 Leu(CUN) 12280 A T Likely neutral 0.340492 0 Leu(CUN) 12281 C A Neutral 0.186514 0 Leu(CUN) 12281 C G Neutral 0.224365 0 Leu(CUN) 12281 C T Neutral 0.183353 0 Leu(CUN) 12282 A C Likely pathogenic 0.536365 1 Leu(CUN) 12282 A G Likely pathogenic 0.536365 1 Leu(CUN) 12282 A T Likely pathogenic 0.536365 1 Leu(CUN) 12283 G A Pathogenic 0.685166 1 Leu(CUN) 12283 G C Pathogenic 0.685166 1 Leu(CUN) 12283 G T Pathogenic 0.685166 1 Leu(CUN) 12284 C A Neutral 0.186112 0 Leu(CUN) 12284 C G Neutral 0.252633 0 Leu(CUN) 12284 C T Neutral 0.181853 0 Leu(CUN) 12285 T A Neutral 0.123361 0 Leu(CUN) 12285 T C Neutral 0.124805 0 Leu(CUN) 12285 T G Neutral 0.214066 0 Leu(CUN) 12286 A C Pathogenic 0.695011 1 Leu(CUN) 12286 A G Pathogenic 0.695011 1 Leu(CUN) 12286 A T Pathogenic 0.672323 1 Leu(CUN) 12287 T A Likely pathogenic 0.538808 1 Leu(CUN) 12287 T C Likely pathogenic 0.538808 1 Leu(CUN) 12287 T G Likely pathogenic 0.538808 1 Leu(CUN) 12288 C A Pathogenic 0.71995 1 Leu(CUN) 12288 C G Pathogenic 0.71995 1 Leu(CUN) 12288 C T Pathogenic 0.71995 1 Leu(CUN) 12289 C A Pathogenic 0.80198 1 Leu(CUN) 12289 C G Pathogenic 0.80198 1 Leu(CUN) 12289 C T Pathogenic 0.80198 1 Leu(CUN) 12290 A C Neutral 0.129599 0 Leu(CUN) 12290 A G Neutral 0.126103 0 Leu(CUN) 12290 A T Neutral 0.188998 0 Leu(CUN) 12291 T A Pathogenic 0.638231 1 Leu(CUN) 12291 T C Pathogenic 0.638231 1 Leu(CUN) 12291 T G Pathogenic 0.638231 1 Leu(CUN) 12292 T A Likely neutral 0.476707 1 Leu(CUN) 12292 T C Likely neutral 0.464699 1 Leu(CUN) 12292 T G Likely neutral 0.476707 1 Leu(CUN) 12293 G A Likely pathogenic 0.632613 1 Leu(CUN) 12293 G C Pathogenic 0.683754 1 Leu(CUN) 12293 G T Pathogenic 0.683754 1 Leu(CUN) 12294 G A Pathogenic 0.801352 1 Leu(CUN) 12294 G C Pathogenic 0.856903 1 Leu(CUN) 12294 G T Pathogenic 0.856903 1 Leu(CUN) 12295 T A Likely neutral 0.411394 0 Leu(CUN) 12295 T C Neutral 0.286664 0 Leu(CUN) 12295 T G Likely neutral 0.411394 0 Leu(CUN) 12296 C A Pathogenic 0.699895 1 Leu(CUN) 12296 C G Pathogenic 0.699895 1 Leu(CUN) 12296 C T Pathogenic 0.699895 1 Leu(CUN) 12297 T A Likely neutral 0.343502 1 Leu(CUN) 12297 T C Likely neutral 0.343502 1 Leu(CUN) 12297 T G Likely neutral 0.343502 1 Leu(CUN) 12298 T A Likely pathogenic 0.581961 1 Leu(CUN) 12298 T C Likely pathogenic 0.581961 1 Leu(CUN) 12298 T G Likely pathogenic 0.581961 1 Leu(CUN) 12299 A C Likely neutral 0.432846 1 Leu(CUN) 12299 A G Likely neutral 0.432846 1 Leu(CUN) 12299 A T Likely neutral 0.432846 1 Leu(CUN) 12300 G A Likely neutral 0.369845 1 Leu(CUN) 12300 G C Likely neutral 0.369845 1 Leu(CUN) 12300 G T Likely neutral 0.369845 1 Leu(CUN) 12301 G A Likely neutral 0.40193 1 Leu(CUN) 12301 G C Likely neutral 0.40193 1 Leu(CUN) 12301 G T Likely neutral 0.40193 1 Leu(CUN) 12302 C A Neutral 0.328089 0 Leu(CUN) 12302 C G Neutral 0.300797 0 Leu(CUN) 12302 C T Neutral 0.300797 0 Leu(CUN) 12303 C A Neutral 0.166913 0 Leu(CUN) 12303 C G Neutral 0.136172 0 Leu(CUN) 12303 C T Neutral 0.210456 0 Leu(CUN) 12304 C A Likely neutral 0.429656 1 Leu(CUN) 12304 C G Likely neutral 0.429656 1 Leu(CUN) 12304 C T Neutral 0.309463 1 Leu(CUN) 12305 C A Pathogenic 0.732438 1 Leu(CUN) 12305 C G Pathogenic 0.732438 1 Leu(CUN) 12305 C T Pathogenic 0.684383 1 Leu(CUN) 12306 A C Likely pathogenic 0.640899 1 Leu(CUN) 12306 A G Likely pathogenic 0.588905 1 Leu(CUN) 12306 A T Likely pathogenic 0.640899 1 Leu(CUN) 12307 A C Pathogenic 0.771652 1 Leu(CUN) 12307 A G Pathogenic 0.771652 1 Leu(CUN) 12307 A T Pathogenic 0.771652 1 Leu(CUN) 12308 A C Likely neutral 0.411662 1 Leu(CUN) 12308 A G Likely neutral 0.411662 1 Leu(CUN) 12308 A T Likely neutral 0.411662 1 Leu(CUN) 12309 A C Likely pathogenic 0.543827 1 Leu(CUN) 12309 A G Likely pathogenic 0.543827 1 Leu(CUN) 12309 A T Likely pathogenic 0.543827 1 Leu(CUN) 12310 A C Pathogenic 0.668408 1 Leu(CUN) 12310 A G Pathogenic 0.668408 1 Leu(CUN) 12310 A T Pathogenic 0.668408 1 Leu(CUN) 12311 T A Neutral 0.109545 0 Leu(CUN) 12311 T C Neutral 0.095802 0 Leu(CUN) 12311 T G Neutral 0.203878 0 Leu(CUN) 12312 T A Neutral 0.22035 0 Leu(CUN) 12312 T C Neutral 0.213065 0 Leu(CUN) 12312 T G Neutral 0.327563 1 Leu(CUN) 12313 T A Pathogenic 0.771386 1 Leu(CUN) 12313 T C Pathogenic 0.771386 1 Leu(CUN) 12313 T G Pathogenic 0.771386 1 Leu(CUN) 12314 T A Likely neutral 0.456958 1 Leu(CUN) 12314 T C Likely neutral 0.456958 1 Leu(CUN) 12314 T G Likely neutral 0.456958 1 Leu(CUN) 12315 G A Pathogenic 0.788893 1 Leu(CUN) 12315 G C Pathogenic 0.788893 1 Leu(CUN) 12315 G T Pathogenic 0.788893 1 Leu(CUN) 12316 G A Pathogenic 0.90568 1 Leu(CUN) 12316 G C Pathogenic 0.90568 1 Leu(CUN) 12316 G T Pathogenic 0.90568 1 Leu(CUN) 12317 T A Likely neutral 0.350222 1 Leu(CUN) 12317 T C Likely neutral 0.350222 1 Leu(CUN) 12317 T G Likely neutral 0.350222 1 Leu(CUN) 12318 G A Likely pathogenic 0.508705 1 Leu(CUN) 12318 G C Likely pathogenic 0.508705 1 Leu(CUN) 12318 G T Likely pathogenic 0.508705 1 Leu(CUN) 12319 C A Likely neutral 0.491812 1 Leu(CUN) 12319 C G Likely pathogenic 0.533615 1 Leu(CUN) 12319 C T Likely pathogenic 0.533615 1 Leu(CUN) 12320 A C Likely pathogenic 0.612614 1 Leu(CUN) 12320 A G Likely pathogenic 0.612614 1 Leu(CUN) 12320 A T Likely pathogenic 0.612614 1 Leu(CUN) 12321 A C Likely pathogenic 0.632571 1 Leu(CUN) 12321 A G Likely pathogenic 0.632571 1 Leu(CUN) 12321 A T Likely pathogenic 0.632571 1 Leu(CUN) 12322 C A Likely neutral 0.360017 1 Leu(CUN) 12322 C G Likely neutral 0.427603 1 Leu(CUN) 12322 C T Likely neutral 0.427603 1 Leu(CUN) 12323 T A Likely pathogenic 0.523591 1 Leu(CUN) 12323 T C Likely pathogenic 0.523591 1 Leu(CUN) 12323 T G Likely pathogenic 0.523591 1 Leu(CUN) 12324 C A Pathogenic 0.71995 1 Leu(CUN) 12324 C G Pathogenic 0.71995 1 Leu(CUN) 12324 C T Pathogenic 0.71995 1 Leu(CUN) 12325 C A Pathogenic 0.80198 1 Leu(CUN) 12325 C G Pathogenic 0.80198 1 Leu(CUN) 12325 C T Pathogenic 0.80198 1 Leu(CUN) 12326 A C Pathogenic 0.737697 1 Leu(CUN) 12326 A G Pathogenic 0.737697 1 Leu(CUN) 12326 A T Pathogenic 0.737697 1 Leu(CUN) 12327 A C Pathogenic 0.771652 1 Leu(CUN) 12327 A G Pathogenic 0.771652 1 Leu(CUN) 12327 A T Pathogenic 0.771652 1 Leu(CUN) 12328 A C Pathogenic 0.837565 1 Leu(CUN) 12328 A G Pathogenic 0.837565 1 Leu(CUN) 12328 A T Pathogenic 0.837565 0 Leu(CUN) 12329 T A Likely pathogenic 0.582519 1 Leu(CUN) 12329 T C Likely pathogenic 0.582519 1 Leu(CUN) 12329 T G Likely pathogenic 0.582519 1 Leu(CUN) 12330 A C Pathogenic 0.648119 1 Leu(CUN) 12330 A G Likely pathogenic 0.590253 1 Leu(CUN) 12330 A T Pathogenic 0.648119 1 Leu(CUN) 12331 A C Pathogenic 0.771652 1 Leu(CUN) 12331 A G Pathogenic 0.771652 1 Leu(CUN) 12331 A T Pathogenic 0.771652 1 Leu(CUN) 12332 A C Pathogenic 0.771652 1 Leu(CUN) 12332 A G Pathogenic 0.771652 1 Leu(CUN) 12332 A T Pathogenic 0.771652 1 Leu(CUN) 12333 A C Likely neutral 0.370474 1 Leu(CUN) 12333 A G Likely neutral 0.370474 1 Leu(CUN) 12333 A T Likely neutral 0.370474 1 Leu(CUN) 12334 G A Pathogenic 0.934854 1 Leu(CUN) 12334 G C Pathogenic 0.934854 1 Leu(CUN) 12334 G T Pathogenic 0.934854 1 Leu(CUN) 12335 T A Likely neutral 0.464235 1 Leu(CUN) 12335 T C Likely neutral 0.377579 1 Leu(CUN) 12335 T G Likely neutral 0.464235 1 Leu(CUN) 12336 A C Likely pathogenic 0.595901 1 Leu(CUN) 12336 A G Likely pathogenic 0.595901 1 Leu(CUN) 12336 A T Likely pathogenic 0.595901 1 Leu(UUR) 3230 G A Likely pathogenic 0.580013 NA Leu(UUR) 3230 G C Pathogenic 0.652515 1 Leu(UUR) 3230 G T Pathogenic 0.652515 1 Leu(UUR) 3231 T A Likely neutral 0.496628 1 Leu(UUR) 3231 T C Likely neutral 0.469042 1 Leu(UUR) 3231 T G Likely neutral 0.496628 1 Leu(UUR) 3232 T A Pathogenic 0.829214 1 Leu(UUR) 3232 T C Pathogenic 0.829214 1 Leu(UUR) 3232 T G Pathogenic 0.829214 1 Leu(UUR) 3233 A C Pathogenic 0.855084 1 Leu(UUR) 3233 A G Pathogenic 0.855084 1 Leu(UUR) 3233 A T Pathogenic 0.855084 1 Leu(UUR) 3234 A C Neutral 0.351727 1 Leu(UUR) 3234 A G Neutral 0.316851 0 Leu(UUR) 3234 A T Neutral 0.351727 1 Leu(UUR) 3235 G A Pathogenic 0.922413 1 Leu(UUR) 3235 G C Pathogenic 0.922413 1 Leu(UUR) 3235 G T Pathogenic 0.922413 1 Leu(UUR) 3236 A C Neutral 0.311796 1 Leu(UUR) 3236 A G Neutral 0.206714 1 Leu(UUR) 3236 A T Neutral 0.311796 1 Leu(UUR) 3237 T A Neutral 0.372367 1 Leu(UUR) 3237 T C Neutral 0.372367 1 Leu(UUR) 3237 T G Neutral 0.372367 1 Leu(UUR) 3238 G A Pathogenic 0.668708 1 Leu(UUR) 3238 G C Pathogenic 0.668708 1 Leu(UUR) 3238 G T Pathogenic 0.668708 1 Leu(UUR) 3239 G A Pathogenic 0.715899 1 Leu(UUR) 3239 G C Pathogenic 0.715899 1 Leu(UUR) 3239 G T Pathogenic 0.715899 1 Leu(UUR) 3240 C A Pathogenic 0.81625 1 Leu(UUR) 3240 C G Pathogenic 0.81625 1 Leu(UUR) 3240 C T Pathogenic 0.81625 1 Leu(UUR) 3241 A C Likely pathogenic 0.617418 1 Leu(UUR) 3241 A G Likely pathogenic 0.617418 1 Leu(UUR) 3241 A T Likely pathogenic 0.617418 1 Leu(UUR) 3242 G A Pathogenic 0.835737 1 Leu(UUR) 3242 G C Pathogenic 0.835737 1 Leu(UUR) 3242 G T Pathogenic 0.835737 1 Leu(UUR) 3243 A C Likely pathogenic 0.732748 1 Leu(UUR) 3243 A G Likely pathogenic 0.732748 1 Leu(UUR) 3243 A T Likely pathogenic 0.732748 1 Leu(UUR) 3244 G A Pathogenic 0.798971 1 Leu(UUR) 3244 G C Pathogenic 0.798971 1 Leu(UUR) 3244 G T Pathogenic 0.798971 1 Leu(UUR) 3245 C A Likely neutral 0.455417 1 Leu(UUR) 3245 C G Likely neutral 0.455417 1 Leu(UUR) 3245 C T Likely neutral 0.411346 1 Leu(UUR) 3246 C A Likely neutral 0.451564 1 Leu(UUR) 3246 C G Likely neutral 0.451564 1 Leu(UUR) 3246 C T Likely neutral 0.419925 1 Leu(UUR) 3247 C A Neutral 0.120887 1 Leu(UUR) 3247 C G Neutral 0.21547 1 Leu(UUR) 3247 C T Neutral 0.125283 1 Leu(UUR) 3248 G A Likely neutral 0.430845 1 Leu(UUR) 3248 G C Likely neutral 0.45555 1 Leu(UUR) 3248 G T Likely neutral 0.45555 1 Leu(UUR) 3249 G A Pathogenic 0.743799 1 Leu(UUR) 3249 G C Pathogenic 0.743799 1 Leu(UUR) 3249 G T Pathogenic 0.743799 1 Leu(UUR) 3250 T A Neutral 0.099735 0 Leu(UUR) 3250 T C Neutral 0.10167 0 Leu(UUR) 3250 T G Neutral 0.196076 0 Leu(UUR) 3251 A C Likely pathogenic 0.616235 1 Leu(UUR) 3251 A G Likely pathogenic 0.667244 1 Leu(UUR) 3251 A T Likely pathogenic 0.667244 1 Leu(UUR) 3252 A C Pathogenic 0.719206 1 Leu(UUR) 3252 A G Pathogenic 0.719206 1 Leu(UUR) 3252 A T Pathogenic 0.719206 1 Leu(UUR) 3253 T A Neutral 0.34383 0 Leu(UUR) 3253 T C Neutral 0.34383 0 Leu(UUR) 3253 T G Likely neutral 0.389886 0 Leu(UUR) 3254 C A Neutral 0.158674 1 Leu(UUR) 3254 C G Neutral 0.158674 1 Leu(UUR) 3254 C T Neutral 0.218172 0 Leu(UUR) 3255 G A Pathogenic 0.726867 1 Leu(UUR) 3255 G C Pathogenic 0.726867 1 Leu(UUR) 3255 G T Pathogenic 0.726867 1 Leu(UUR) 3256 C A Pathogenic 0.81625 1 Leu(UUR) 3256 C G Pathogenic 0.81625 1 Leu(UUR) 3256 C T Pathogenic 0.81625 1 Leu(UUR) 3257 A C Neutral 0.241024 1 Leu(UUR) 3257 A G Neutral 0.24403 1 Leu(UUR) 3257 A T Neutral 0.273054 1 Leu(UUR) 3258 T A Likely pathogenic 0.669007 1 Leu(UUR) 3258 T C Likely pathogenic 0.724173 1 Leu(UUR) 3258 T G Likely pathogenic 0.669007 1 Leu(UUR) 3259 A C Pathogenic 0.855084 1 Leu(UUR) 3259 A G Pathogenic 0.855084 1 Leu(UUR) 3259 A T Pathogenic 0.855084 1 Leu(UUR) 3260 A C Pathogenic 0.827889 1 Leu(UUR) 3260 A G Pathogenic 0.827889 1 Leu(UUR) 3260 A T Pathogenic 0.827889 1 Leu(UUR) 3261 A C Likely pathogenic 0.538591 1 Leu(UUR) 3261 A G Likely neutral 0.486165 1 Leu(UUR) 3261 A T Likely pathogenic 0.538591 1 Leu(UUR) 3262 A C Likely pathogenic 0.564079 1 Leu(UUR) 3262 A G Likely pathogenic 0.536019 1 Leu(UUR) 3262 A T Likely pathogenic 0.564079 1 Leu(UUR) 3263 C A Likely neutral 0.448912 0 Leu(UUR) 3263 C G Likely neutral 0.448912 0 Leu(UUR) 3263 C T Likely neutral 0.408839 0 Leu(UUR) 3264 T A Likely neutral 0.3832 1 Leu(UUR) 3264 T C Likely neutral 0.3832 1 Leu(UUR) 3264 T G Likely neutral 0.3832 1 Leu(UUR) 3265 T A Likely pathogenic 0.658185 1 Leu(UUR) 3265 T C Likely pathogenic 0.658185 1 Leu(UUR) 3265 T G Likely pathogenic 0.658185 1 Leu(UUR) 3266 A C Pathogenic 0.730303 1 Leu(UUR) 3266 A G Pathogenic 0.730303 1 Leu(UUR) 3266 A T Pathogenic 0.730303 1 Leu(UUR) 3267 A C Pathogenic 0.69395 1 Leu(UUR) 3267 A G Pathogenic 0.69395 1 Leu(UUR) 3267 A T Pathogenic 0.69395 1 Leu(UUR) 3268 A C Likely neutral 0.438823 0 Leu(UUR) 3268 A G Likely neutral 0.327749 0 Leu(UUR) 3268 A T Likely neutral 0.438823 0 Leu(UUR) 3269 A C Likely neutral 0.428887 1 Leu(UUR) 3269 A G Likely neutral 0.392283 0 Leu(UUR) 3269 A T Likely pathogenic 0.507738 1 Leu(UUR) 3270 C A Likely pathogenic 0.524454 0 Leu(UUR) 3270 C G Likely pathogenic 0.524454 0 Leu(UUR) 3270 C T Likely neutral 0.481341 0 Leu(UUR) 3271 T A Likely pathogenic 0.540765 1 Leu(UUR) 3271 T C Likely pathogenic 0.634749 1 Leu(UUR) 3271 T G Likely pathogenic 0.540765 1 Leu(UUR) 3272 T A Pathogenic 0.79398 1 Leu(UUR) 3272 T C Pathogenic 0.79398 1 Leu(UUR) 3272 T G Pathogenic 0.79398 1 Leu(UUR) 3273 T A Pathogenic 0.829214 1 Leu(UUR) 3273 T C Pathogenic 0.829214 1 Leu(UUR) 3273 T G Pathogenic 0.829214 1 Leu(UUR) 3274 A C Neutral 0.352845 1 Leu(UUR) 3274 A G Neutral 0.262483 1 Leu(UUR) 3274 A T Neutral 0.352845 1 Leu(UUR) 3275 C A Neutral 0.141367 0 Leu(UUR) 3275 C G Neutral 0.246902 0 Leu(UUR) 3275 C T Neutral 0.179554 0 Leu(UUR) 3276 A C Neutral 0.203655 1 Leu(UUR) 3276 A G Neutral 0.203655 1 Leu(UUR) 3276 A T Neutral 0.14992 1 Leu(UUR) 3277 G A Neutral 0.271769 0 Leu(UUR) 3277 G C Neutral 0.262894 0 Leu(UUR) 3277 G T Neutral 0.274865 0 Leu(UUR) 3278 T A Neutral 0.226699 0 Leu(UUR) 3278 T C Neutral 0.16003 0 Leu(UUR) 3278 T G Neutral 0.279066 0 Leu(UUR) 3279 C A Pathogenic 0.842087 1 Leu(UUR) 3279 C G Pathogenic 0.842087 1 Leu(UUR) 3279 C T Pathogenic 0.842087 1 Leu(UUR) 3280 A C Pathogenic 0.745681 1 Leu(UUR) 3280 A G Pathogenic 0.745681 1 Leu(UUR) 3280 A T Pathogenic 0.745681 1 Leu(UUR) 3281 G A Pathogenic 0.922413 1 Leu(UUR) 3281 G C Pathogenic 0.922413 1 Leu(UUR) 3281 G T Pathogenic 0.922413 1 Leu(UUR) 3282 A C Pathogenic 0.682441 1 Leu(UUR) 3282 A G Pathogenic 0.682441 1 Leu(UUR) 3282 A T Pathogenic 0.682441 1 Leu(UUR) 3283 G A Likely pathogenic 0.569971 1 Leu(UUR) 3283 G C Likely pathogenic 0.576816 1 Leu(UUR) 3283 G T Likely pathogenic 0.576816 1 Leu(UUR) 3284 G A Pathogenic 0.84375 1 Leu(UUR) 3284 G C Pathogenic 0.894716 1 Leu(UUR) 3284 G T Pathogenic 0.894716 1 Leu(UUR) 3285 T A Likely neutral 0.383842 1 Leu(UUR) 3285 T C Likely neutral 0.383842 1 Leu(UUR) 3285 T G Likely neutral 0.383842 1 Leu(UUR) 3286 T A Likely neutral 0.383662 1 Leu(UUR) 3286 T C Likely neutral 0.383662 1 Leu(UUR) 3286 T G Likely neutral 0.383662 1 Leu(UUR) 3287 C A Pathogenic 0.842728 1 Leu(UUR) 3287 C G Pathogenic 0.842728 1 Leu(UUR) 3287 C T Pathogenic 0.842728 1 Leu(UUR) 3288 A C Likely pathogenic 0.582711 1 Leu(UUR) 3288 A G Likely pathogenic 0.511551 1 Leu(UUR) 3288 A T Likely pathogenic 0.582711 1 Leu(UUR) 3289 A C Pathogenic 0.719206 1 Leu(UUR) 3289 A G Pathogenic 0.719206 1 Leu(UUR) 3289 A T Pathogenic 0.719206 1 Leu(UUR) 3290 T A Neutral 0.103678 0 Leu(UUR) 3290 T C Neutral 0.129745 0 Leu(UUR) 3290 T G Neutral 0.192212 0 Leu(UUR) 3291 T A Neutral 0.333462 0 Leu(UUR) 3291 T C Neutral 0.226115 0 Leu(UUR) 3291 T G Neutral 0.333462 0 Leu(UUR) 3292 C A Pathogenic 0.720907 1 Leu(UUR) 3292 C G Pathogenic 0.720907 1 Leu(UUR) 3292 C T Likely pathogenic 0.698818 1 Leu(UUR) 3293 C A Pathogenic 0.781319 1 Leu(UUR) 3293 C G Pathogenic 0.781319 1 Leu(UUR) 3293 C T Pathogenic 0.781319 1 Leu(UUR) 3294 T A Pathogenic 0.719823 1 Leu(UUR) 3294 T C Pathogenic 0.719823 1 Leu(UUR) 3294 T G Pathogenic 0.719823 1 Leu(UUR) 3295 C A Pathogenic 0.87982 1 Leu(UUR) 3295 C G Pathogenic 0.87982 1 Leu(UUR) 3295 C T Pathogenic 0.87982 1 Leu(UUR) 3296 T A Likely pathogenic 0.557289 1 Leu(UUR) 3296 T C Likely pathogenic 0.557289 1 Leu(UUR) 3296 T G Likely pathogenic 0.557289 1 Leu(UUR) 3297 T A Neutral 0.293537 1 Leu(UUR) 3297 T C Neutral 0.197522 1 Leu(UUR) 3297 T G Neutral 0.293537 1 Leu(UUR) 3298 C A Pathogenic 0.87982 1 Leu(UUR) 3298 C G Pathogenic 0.87982 1 Leu(UUR) 3298 C T Pathogenic 0.87982 1 Leu(UUR) 3299 T A Likely pathogenic 0.540765 1 Leu(UUR) 3299 T C Likely pathogenic 0.634749 0 Leu(UUR) 3299 T G Likely pathogenic 0.540765 1 Leu(UUR) 3300 T A Pathogenic 0.829214 1 Leu(UUR) 3300 T C Pathogenic 0.829214 1 Leu(UUR) 3300 T G Pathogenic 0.829214 1 Leu(UUR) 3301 A C Pathogenic 0.807423 1 Leu(UUR) 3301 A G Pathogenic 0.777312 1 Leu(UUR) 3301 A T Pathogenic 0.807423 1 Leu(UUR) 3302 A C Likely pathogenic 0.696009 1 Leu(UUR) 3302 A G Likely pathogenic 0.67022 1 Leu(UUR) 3302 A T Likely pathogenic 0.696009 1 Leu(UUR) 3303 C A Pathogenic 0.640393 1 Leu(UUR) 3303 C G Pathogenic 0.640393 1 Leu(UUR) 3303 C T Likely pathogenic 0.593495 1 Leu(UUR) 3304 A C Likely pathogenic 0.621974 1 Leu(UUR) 3304 A G Likely pathogenic 0.621974 1 Leu(UUR) 3304 A T Likely pathogenic 0.621974 1 Lys 8295 C A Pathogenic 0.75487 1 Lys 8295 C G Pathogenic 0.75487 1 Lys 8295 C T Pathogenic 0.75487 1 Lys 8296 A C Likely neutral 0.409524 1 Lys 8296 A G Neutral 0.256305 1 Lys 8296 A T Likely neutral 0.409524 1 Lys 8297 C A Likely neutral 0.469811 1 Lys 8297 C G Likely neutral 0.469811 1 Lys 8297 C T Likely neutral 0.433864 1 Lys 8298 T A Likely pathogenic 0.574268 1 Lys 8298 T C Likely pathogenic 0.557713 1 Lys 8298 T G Likely pathogenic 0.574268 1 Lys 8299 G A Likely neutral 0.355078 1 Lys 8299 G C Likely neutral 0.439799 1 Lys 8299 G T Likely neutral 0.439799 1 Lys 8300 T A Likely neutral 0.476341 1 Lys 8300 T C Likely neutral 0.451013 0 Lys 8300 T G Likely neutral 0.476341 1 Lys 8301 A C Neutral 0.277752 1 Lys 8301 A G Neutral 0.163032 1 Lys 8301 A T Neutral 0.277752 1 Lys 8302 A C Neutral 0.20828 0 Lys 8302 A G Neutral 0.250338 0 Lys 8302 A T Neutral 0.229031 0 Lys 8303 A C Likely neutral 0.420677 1 Lys 8303 A G Likely neutral 0.420677 1 Lys 8303 A T Likely neutral 0.420677 1 Lys 8304 G A Pathogenic 0.840736 1 Lys 8304 G C Pathogenic 0.840736 1 Lys 8304 G T Pathogenic 0.840736 1 Lys 8305 C A Pathogenic 0.733736 1 Lys 8305 C G Pathogenic 0.733736 1 Lys 8305 C T Pathogenic 0.733736 1 Lys 8306 T A Likely pathogenic 0.609704 1 Lys 8306 T C Likely pathogenic 0.609704 1 Lys 8306 T G Likely pathogenic 0.609704 1 Lys 8307 A C Likely pathogenic 0.510467 1 Lys 8307 A G Likely neutral 0.484182 0 Lys 8307 A T Likely neutral 0.410387 0 Lys 8308 A C Neutral 0.13199 0 Lys 8308 A G Neutral 0.161329 0 Lys 8308 A T Neutral 0.098319 0 Lys 8309 C A Neutral 0.195639 0 Lys 8309 C G Neutral 0.187254 0 Lys 8309 C T Neutral 0.196899 0 Lys 8310 T A Neutral 0.151379 0 Lys 8310 T C Neutral 0.143926 0 Lys 8310 T G Neutral 0.208629 0 Lys 8311 T A Neutral 0.202106 0 Lys 8311 T C Neutral 0.202106 0 Lys 8311 T G Neutral 0.26863 1 Lys 8312 A C Likely pathogenic 0.56842 1 Lys 8312 A G Likely pathogenic 0.56842 1 Lys 8312 A T Likely pathogenic 0.56842 1 Lys 8313 G A Pathogenic 0.845407 1 Lys 8313 G C Pathogenic 0.845407 1 Lys 8313 G T Pathogenic 0.845407 1 Lys 8314 C A Pathogenic 0.704565 1 Lys 8314 C G Pathogenic 0.704565 1 Lys 8314 C T Pathogenic 0.704565 1 Lys 8315 A C Neutral 0.207551 0 Lys 8315 A G Neutral 0.151324 0 Lys 8315 A T Neutral 0.207551 0 Lys 8316 T A Likely neutral 0.470578 1 Lys 8316 T C Likely neutral 0.390029 1 Lys 8316 T G Likely neutral 0.470578 1 Lys 8317 T A Pathogenic 0.714553 1 Lys 8317 T C Pathogenic 0.714553 1 Lys 8317 T G Pathogenic 0.714553 1 Lys 8318 A C Likely pathogenic 0.648689 1 Lys 8318 A G Likely pathogenic 0.648689 1 Lys 8318 A T Likely pathogenic 0.648689 1 Lys 8319 A C Likely neutral 0.484068 1 Lys 8319 A G Likely neutral 0.331588 1 Lys 8319 A T Likely neutral 0.484068 1 Lys 8320 C A Likely pathogenic 0.613414 1 Lys 8320 C G Likely pathogenic 0.613414 1 Lys 8320 C T Likely pathogenic 0.613414 1 Lys 8321 C A Likely pathogenic 0.515981 1 Lys 8321 C G Likely pathogenic 0.515981 1 Lys 8321 C T Likely pathogenic 0.515981 1 Lys 8322 T A Likely neutral 0.317038 1 Lys 8322 T C Likely neutral 0.317038 1 Lys 8322 T G Likely neutral 0.317038 1 Lys 8323 T A Likely neutral 0.441868 1 Lys 8323 T C Likely neutral 0.441868 1 Lys 8323 T G Likely neutral 0.441868 1 Lys 8324 T A Likely neutral 0.441868 1 Lys 8324 T C Likely neutral 0.441868 1 Lys 8324 T G Likely neutral 0.441868 1 Lys 8325 T A Likely neutral 0.494633 1 Lys 8325 T C Likely neutral 0.494633 1 Lys 8325 T G Likely neutral 0.494633 1 Lys 8326 A C Likely neutral 0.41359 1 Lys 8326 A G Likely neutral 0.41359 1 Lys 8326 A T Likely neutral 0.41359 1 Lys 8327 A C Neutral 0.320997 1 Lys 8327 A G Neutral 0.320997 1 Lys 8327 A T Neutral 0.320997 1 Lys 8328 G A Pathogenic 0.920617 1 Lys 8328 G C Pathogenic 0.920617 1 Lys 8328 G T Pathogenic 0.920617 1 Lys 8329 T A Likely neutral 0.353742 1 Lys 8329 T C Neutral 0.297142 1 Lys 8329 T G Likely neutral 0.353742 1 Lys 8330 T A Pathogenic 0.714553 1 Lys 8330 T C Pathogenic 0.714553 1 Lys 8330 T G Pathogenic 0.714553 1 Lys 8331 A C Likely pathogenic 0.648689 1 Lys 8331 A G Likely pathogenic 0.648689 1 Lys 8331 A T Likely pathogenic 0.648689 1 Lys 8332 A C Likely pathogenic 0.528613 1 Lys 8332 A G Likely neutral 0.413731 1 Lys 8332 A T Likely pathogenic 0.528613 1 Lys 8333 A C Likely neutral 0.391217 1 Lys 8333 A G Likely neutral 0.391217 1 Lys 8333 A T Likely neutral 0.391217 1 Lys 8334 G A Pathogenic 0.675288 1 Lys 8334 G C Pathogenic 0.720936 1 Lys 8334 G T Pathogenic 0.720936 1 Lys 8335 A C Likely neutral 0.488735 1 Lys 8335 A G Likely neutral 0.488735 1 Lys 8335 A T Likely neutral 0.42312 1 Lys 8336 T A Neutral 0.100849 0 Lys 8336 T C Neutral 0.107897 0 Lys 8336 T G Neutral 0.148433 0 Lys 8337 T A Neutral 0.133522 0 Lys 8337 T C Neutral 0.146347 0 Lys 8337 T G Neutral 0.141034 0 Lys 8338 A C Neutral 0.352349 1 Lys 8338 A G Neutral 0.277054 1 Lys 8338 A T Neutral 0.352349 1 Lys 8339 A C Neutral 0.339333 1 Lys 8339 A G Neutral 0.30676 0 Lys 8339 A T Neutral 0.339333 1 Lys 8340 G A Likely pathogenic 0.680551 1 Lys 8340 G C Pathogenic 0.737344 1 Lys 8340 G T Pathogenic 0.737344 1 Lys 8341 A C Neutral 0.363408 1 Lys 8341 A G Neutral 0.315032 1 Lys 8341 A T Likely neutral 0.41479 1 Lys 8342 G A Likely pathogenic 0.515229 0 Lys 8342 G C Likely pathogenic 0.501246 1 Lys 8342 G T Likely pathogenic 0.536113 1 Lys 8343 A C Neutral 0.100926 0 Lys 8343 A G Neutral 0.100926 0 Lys 8343 A T Neutral 0.105285 0 Lys 8344 A C Neutral 0.201723 0 Lys 8344 A G Likely neutral 0.421511 0 Lys 8344 A T Neutral 0.200497 0 Lys 8345 C A Neutral 0.104156 0 Lys 8345 C G Neutral 0.162753 0 Lys 8345 C T Neutral 0.105464 0 Lys 8346 C A Neutral 0.139255 0 Lys 8346 C G Neutral 0.209486 0 Lys 8346 C T Neutral 0.133954 0 Lys 8347 A C Neutral 0.109275 0 Lys 8347 A G Neutral 0.082719 0 Lys 8347 A T Neutral 0.231454 0 Lys 8348 A C Neutral 0.17732 0 Lys 8348 A G Neutral 0.227084 0 Lys 8348 A T Neutral 0.186225 0 Lys 8349 C A Neutral 0.181366 0 Lys 8349 C G Neutral 0.236948 0 Lys 8349 C T Neutral 0.173425 0 Lys 8350 A C Neutral 0.096582 0 Lys 8350 A G Neutral 0.176164 0 Lys 8350 A T Neutral 0.106679 0 Lys 8351 C A Neutral 0.127376 0 Lys 8351 C G Neutral 0.169921 0 Lys 8351 C T Neutral 0.114843 0 Lys 8352 C A Neutral 0.228614 1 Lys 8352 C G Neutral 0.288908 1 Lys 8352 C T Neutral 0.226689 0 Lys 8353 T A Likely pathogenic 0.544106 1 Lys 8353 T C Likely neutral 0.446467 1 Lys 8353 T G Likely pathogenic 0.544106 1 Lys 8354 C A Pathogenic 0.703726 1 Lys 8354 C G Pathogenic 0.689661 1 Lys 8354 C T Pathogenic 0.656646 1 Lys 8355 T A Likely pathogenic 0.515457 1 Lys 8355 T C Likely pathogenic 0.598657 0 Lys 8355 T G Likely pathogenic 0.515457 1 Lys 8356 T A Likely neutral 0.463534 1 Lys 8356 T C Likely neutral 0.477805 1 Lys 8356 T G Likely neutral 0.463534 1 Lys 8357 T A Neutral 0.316351 1 Lys 8357 T C Neutral 0.226011 1 Lys 8357 T G Neutral 0.316351 1 Lys 8358 A C Neutral 0.320745 1 Lys 8358 A G Neutral 0.233102 0 Lys 8358 A T Neutral 0.320745 1 Lys 8359 C A Likely neutral 0.465578 1 Lys 8359 C G Likely neutral 0.465578 1 Lys 8359 C T Likely neutral 0.398332 1 Lys 8360 A C Likely pathogenic 0.640941 1 Lys 8360 A G Likely pathogenic 0.640941 1 Lys 8360 A T Likely pathogenic 0.640941 1 Lys 8361 G A Likely neutral 0.461656 1 Lys 8361 G C Likely pathogenic 0.546806 1 Lys 8361 G T Likely pathogenic 0.546806 1 Lys 8362 T A Likely pathogenic 0.580395 1 Lys 8362 T C Likely pathogenic 0.555092 1 Lys 8362 T G Likely pathogenic 0.580395 1 Lys 8363 G A Pathogenic 0.868016 1 Lys 8363 G C Pathogenic 0.868016 1 Lys 8363 G T Pathogenic 0.868016 1 Lys 8364 A C Neutral 0.34192 1 Lys 8364 A G Neutral 0.270775 1 Lys 8364 A T Neutral 0.34192 1 Met 4402 A C Likely neutral 0.398614 1 Met 4402 A G Likely neutral 0.398614 1 Met 4402 A T Likely neutral 0.398614 1 Met 4403 G A Pathogenic 0.952477 1 Met 4403 G C Pathogenic 0.952477 1 Met 4403 G T Pathogenic 0.952477 1 Met 4404 T A Likely pathogenic 0.619131 1 Met 4404 T C Likely pathogenic 0.619131 1 Met 4404 T G Likely pathogenic 0.619131 1 Met 4405 A C Pathogenic 0.855084 1 Met 4405 A G Pathogenic 0.855084 1 Met 4405 A T Pathogenic 0.855084 1 Met 4406 A C Likely neutral 0.347471 1 Met 4406 A G Likely neutral 0.347471 1 Met 4406 A T Likely neutral 0.347471 1 Met 4407 G A Likely pathogenic 0.659084 1 Met 4407 G C Likely pathogenic 0.659084 1 Met 4407 G T Likely pathogenic 0.659084 1 Met 4408 G A Pathogenic 0.922515 1 Met 4408 G C Pathogenic 0.922515 1 Met 4408 G T Pathogenic 0.922515 1 Met 4409 T A Likely pathogenic 0.700112 1 Met 4409 T C Likely pathogenic 0.700112 1 Met 4409 T G Likely pathogenic 0.700112 1 Met 4410 C A Pathogenic 0.844777 1 Met 4410 C G Pathogenic 0.844777 1 Met 4410 C T Pathogenic 0.844777 1 Met 4411 A C Pathogenic 0.792798 1 Met 4411 A G Pathogenic 0.792798 1 Met 4411 A T Pathogenic 0.792798 1 Met 4412 G A Pathogenic 0.916975 1 Met 4412 G C Pathogenic 0.916975 1 Met 4412 G T Pathogenic 0.916975 1 Met 4413 C A Pathogenic 0.762294 1 Met 4413 C G Pathogenic 0.762294 1 Met 4413 C T Pathogenic 0.707162 1 Met 4414 T A Pathogenic 0.668027 1 Met 4414 T C Pathogenic 0.668027 1 Met 4414 T G Pathogenic 0.668027 1 Met 4415 A C Pathogenic 0.773953 1 Met 4415 A G Pathogenic 0.773953 1 Met 4415 A T Pathogenic 0.773953 1 Met 4416 A C Pathogenic 0.715471 1 Met 4416 A G Pathogenic 0.715471 1 Met 4416 A T Pathogenic 0.715471 1 Met 4417 A C Neutral 0.264208 1 Met 4417 A G Neutral 0.264208 1 Met 4417 A T Neutral 0.201621 1 Met 4418 T A Likely neutral 0.389745 0 Met 4418 T C Neutral 0.320825 0 Met 4418 T G Likely neutral 0.400149 0 Met 4419 A C Pathogenic 0.730303 1 Met 4419 A G Pathogenic 0.730303 1 Met 4419 A T Pathogenic 0.730303 1 Met 4420 A C Likely pathogenic 0.552649 1 Met 4420 A G Likely pathogenic 0.552649 1 Met 4420 A T Likely pathogenic 0.552649 1 Met 4421 G A Pathogenic 0.918634 1 Met 4421 G C Pathogenic 0.918634 1 Met 4421 G T Pathogenic 0.918634 1 Met 4422 C A Pathogenic 0.825152 1 Met 4422 C G Pathogenic 0.825152 1 Met 4422 C T Pathogenic 0.825152 1 Met 4423 T A Pathogenic 0.668027 1 Met 4423 T C Pathogenic 0.668027 1 Met 4423 T G Pathogenic 0.668027 1 Met 4424 A C Likely pathogenic 0.628679 1 Met 4424 A G Likely pathogenic 0.628679 1 Met 4424 A T Likely pathogenic 0.628679 1 Met 4425 T A Likely pathogenic 0.55278 1 Met 4425 T C Likely pathogenic 0.55278 1 Met 4425 T G Likely pathogenic 0.55278 1 Met 4426 C A Pathogenic 0.663036 1 Met 4426 C G Pathogenic 0.663036 1 Met 4426 C T Likely pathogenic 0.640334 1 Met 4427 G A Pathogenic 0.654715 1 Met 4427 G C Pathogenic 0.654715 1 Met 4427 G T Pathogenic 0.654715 1 Met 4428 G A Likely pathogenic 0.662798 1 Met 4428 G C Likely pathogenic 0.662798 1 Met 4428 G T Likely pathogenic 0.662798 1 Met 4429 G A Pathogenic 0.671012 1 Met 4429 G C Pathogenic 0.671012 1 Met 4429 G T Pathogenic 0.671012 1 Met 4430 C A Likely pathogenic 0.53996 1 Met 4430 C G Likely pathogenic 0.53996 1 Met 4430 C T Likely pathogenic 0.53996 1 Met 4431 C A Likely neutral 0.472365 1 Met 4431 C G Likely neutral 0.472365 1 Met 4431 C T Likely neutral 0.472365 1 Met 4432 C A Pathogenic 0.690443 1 Met 4432 C G Pathogenic 0.690443 1 Met 4432 C T Pathogenic 0.690443 1 Met 4433 A C Likely neutral 0.498595 1 Met 4433 A G Likely neutral 0.498595 1 Met 4433 A T Likely neutral 0.498595 1 Met 4434 T A Likely pathogenic 0.548361 1 Met 4434 T C Likely pathogenic 0.548361 1 Met 4434 T G Likely pathogenic 0.548361 1 Met 4435 A C Likely neutral 0.492288 1 Met 4435 A G Likely neutral 0.492288 1 Met 4435 A T Likely neutral 0.492288 1 Met 4436 C A Likely pathogenic 0.565533 1 Met 4436 C G Likely pathogenic 0.565533 1 Met 4436 C T Likely pathogenic 0.565533 1 Met 4437 C A Likely pathogenic 0.598646 1 Met 4437 C G Likely pathogenic 0.598646 1 Met 4437 C T Likely pathogenic 0.598646 1 Met 4438 C A Likely pathogenic 0.598646 1 Met 4438 C G Likely pathogenic 0.598646 1 Met 4438 C T Likely pathogenic 0.598646 1 Met 4439 C A Likely pathogenic 0.610936 1 Met 4439 C G Likely pathogenic 0.610936 1 Met 4439 C T Likely pathogenic 0.610936 1 Met 4440 G A Pathogenic 0.887304 1 Met 4440 G C Pathogenic 0.887304 1 Met 4440 G T Pathogenic 0.887304 1 Met 4441 A C Likely pathogenic 0.547549 1 Met 4441 A G Likely pathogenic 0.547549 1 Met 4441 A T Likely pathogenic 0.547549 1 Met 4442 A C Likely pathogenic 0.525229 1 Met 4442 A G Likely pathogenic 0.525229 1 Met 4442 A T Likely pathogenic 0.525229 1 Met 4443 A C Likely pathogenic 0.652921 1 Met 4443 A G Likely pathogenic 0.652921 1 Met 4443 A T Likely pathogenic 0.652921 1 Met 4444 A C Pathogenic 0.67268 1 Met 4444 A G Likely pathogenic 0.630286 1 Met 4444 A T Pathogenic 0.67268 1 Met 4445 T A Likely neutral 0.362784 1 Met 4445 T C Neutral 0.320363 1 Met 4445 T G Likely neutral 0.362784 1 Met 4446 G A Pathogenic 0.905866 1 Met 4446 G C Pathogenic 0.905866 1 Met 4446 G T Pathogenic 0.905866 1 Met 4447 T A Likely neutral 0.422137 1 Met 4447 T C Likely neutral 0.422137 1 Met 4447 T G Likely neutral 0.422137 1 Met 4448 T A Likely neutral 0.363648 1 Met 4448 T C Neutral 0.359222 0 Met 4448 T G Likely neutral 0.363648 1 Met 4449 G A Pathogenic 0.816939 1 Met 4449 G C Pathogenic 0.816939 1 Met 4449 G T Pathogenic 0.816939 1 Met 4450 G A Pathogenic 0.922515 1 Met 4450 G C Pathogenic 0.922515 1 Met 4450 G T Pathogenic 0.922515 1 Met 4451 T A Neutral 0.2483 1 Met 4451 T C Neutral 0.232936 1 Met 4451 T G Neutral 0.2483 1 Met 4452 T A Neutral 0.153923 0 Met 4452 T C Neutral 0.110407 0 Met 4452 T G Neutral 0.241129 0 Met 4453 A C Likely pathogenic 0.608066 1 Met 4453 A G Likely pathogenic 0.608066 1 Met 4453 A T Likely pathogenic 0.566102 1 Met 4454 T A Neutral 0.12881 0 Met 4454 T C Neutral 0.129075 0 Met 4454 T G Neutral 0.237262 0 Met 4455 A C Neutral 0.264562 1 Met 4455 A G Neutral 0.341734 1 Met 4455 A T Neutral 0.341734 1 Met 4456 C A Neutral 0.227891 0 Met 4456 C G Neutral 0.227891 0 Met 4456 C T Neutral 0.167176 0 Met 4457 C A Likely pathogenic 0.598646 1 Met 4457 C G Likely pathogenic 0.598646 1 Met 4457 C T Likely pathogenic 0.598646 1 Met 4458 C A Pathogenic 0.769591 1 Met 4458 C G Pathogenic 0.769591 1 Met 4458 C T Pathogenic 0.769591 1 Met 4459 T A Likely neutral 0.379894 1 Met 4459 T C Likely neutral 0.391743 0 Met 4459 T G Likely neutral 0.379894 1 Met 4460 T A Likely neutral 0.406193 1 Met 4460 T C Likely neutral 0.406193 1 Met 4460 T G Likely neutral 0.406193 1 Met 4461 C A Pathogenic 0.755523 1 Met 4461 C G Pathogenic 0.755523 1 Met 4461 C T Pathogenic 0.755523 1 Met 4462 C A Likely pathogenic 0.598646 1 Met 4462 C G Likely pathogenic 0.598646 1 Met 4462 C T Likely pathogenic 0.598646 1 Met 4463 C A Likely pathogenic 0.610936 1 Met 4463 C G Likely pathogenic 0.610936 1 Met 4463 C T Likely pathogenic 0.610936 1 Met 4464 G A Likely neutral 0.475617 0 Met 4464 G C Likely neutral 0.475617 0 Met 4464 G T Likely pathogenic 0.500925 0 Met 4465 T A Likely pathogenic 0.619131 1 Met 4465 T C Likely pathogenic 0.619131 1 Met 4465 T G Likely pathogenic 0.619131 1 Met 4466 A C Likely pathogenic 0.545183 1 Met 4466 A G Likely pathogenic 0.545183 1 Met 4466 A T Likely pathogenic 0.545183 1 Met 4467 C A Pathogenic 0.781012 1 Met 4467 C G Pathogenic 0.781012 1 Met 4467 C T Pathogenic 0.781012 1 Met 4468 T A Pathogenic 0.668027 1 Met 4468 T C Pathogenic 0.668027 1 Met 4468 T G Pathogenic 0.668027 1 Met 4469 A C Pathogenic 0.711029 1 Met 4469 A G Pathogenic 0.711029 1 Met 4469 A T Pathogenic 0.711029 1 Phe 577 G A Pathogenic 0.934854 1 Phe 577 G C Pathogenic 0.934854 1 Phe 577 G T Pathogenic 0.934854 1 Phe 578 T A Likely pathogenic 0.520981 1 Phe 578 T C Likely pathogenic 0.520981 1 Phe 578 T G Likely pathogenic 0.520981 1 Phe 579 T A Pathogenic 0.771386 1 Phe 579 T C Pathogenic 0.771386 1 Phe 579 T G Pathogenic 0.771386 1 Phe 580 T A Neutral 0.200147 0 Phe 580 T C Neutral 0.216831 1 Phe 580 T G Neutral 0.216831 0 Phe 581 A C Pathogenic 0.711124 1 Phe 581 A G Pathogenic 0.682377 1 Phe 581 A T Pathogenic 0.711124 1 Phe 582 T A Likely neutral 0.384262 1 Phe 582 T C Likely neutral 0.464169 1 Phe 582 T G Likely neutral 0.384262 1 Phe 583 G A Pathogenic 0.899313 1 Phe 583 G C Pathogenic 0.899313 1 Phe 583 G T Pathogenic 0.899313 1 Phe 584 T A Likely neutral 0.482597 1 Phe 584 T C Likely neutral 0.482597 1 Phe 584 T G Likely neutral 0.482597 1 Phe 585 A C Likely neutral 0.468085 1 Phe 585 A G Likely neutral 0.468085 1 Phe 585 A T Likely neutral 0.468085 1 Phe 586 G A Pathogenic 0.871132 1 Phe 586 G C Pathogenic 0.871132 1 Phe 586 G T Pathogenic 0.871132 1 Phe 587 C A Pathogenic 0.77927 1 Phe 587 C G Pathogenic 0.77927 1 Phe 587 C T Pathogenic 0.77927 1 Phe 588 T A Likely pathogenic 0.528246 1 Phe 588 T C Likely pathogenic 0.528246 1 Phe 588 T G Likely pathogenic 0.528246 1 Phe 589 T A Pathogenic 0.775779 1 Phe 589 T C Pathogenic 0.775779 1 Phe 589 T G Pathogenic 0.775779 1 Phe 590 A C Likely neutral 0.497037 1 Phe 590 A G Likely neutral 0.497037 1 Phe 590 A T Likely neutral 0.497037 1 Phe 591 C A Neutral 0.148525 0 Phe 591 C G Neutral 0.160122 0 Phe 591 C T Neutral 0.11483 0 Phe 592 C A Neutral 0.170547 0 Phe 592 C G Neutral 0.26048 0 Phe 592 C T Neutral 0.200404 0 Phe 593 T A Neutral 0.159431 0 Phe 593 T C Neutral 0.159431 0 Phe 593 T G Neutral 0.283813 0 Phe 594 C A Neutral 0.115895 0 Phe 594 C G Neutral 0.178229 0 Phe 594 C T Neutral 0.115981 0 Phe 595 C A Neutral 0.141571 0 Phe 595 C G Neutral 0.202378 0 Phe 595 C T Neutral 0.141805 0 Phe 596 T A Neutral 0.163953 0 Phe 596 T C Neutral 0.159895 0 Phe 596 T G Neutral 0.281721 0 Phe 597 C A Neutral 0.346628 0 Phe 597 C G Neutral 0.346628 0 Phe 597 C T Neutral 0.210512 0 Phe 598 A C Likely pathogenic 0.612614 1 Phe 598 A G Likely pathogenic 0.612614 1 Phe 598 A T Likely pathogenic 0.612614 1 Phe 599 A C Pathogenic 0.73642 1 Phe 599 A G Pathogenic 0.73642 1 Phe 599 A T Pathogenic 0.73642 1 Phe 600 A C Likely neutral 0.484202 1 Phe 600 A G Likely neutral 0.484202 1 Phe 600 A T Likely neutral 0.484202 1 Phe 601 G A Pathogenic 0.878552 1 Phe 601 G C Pathogenic 0.878552 1 Phe 601 G T Pathogenic 0.878552 1 Phe 602 C A Pathogenic 0.736641 1 Phe 602 C G Pathogenic 0.736641 1 Phe 602 C T Pathogenic 0.736641 1 Phe 603 A C Likely neutral 0.467843 1 Phe 603 A G Likely neutral 0.420688 1 Phe 603 A T Likely neutral 0.467843 1 Phe 604 A C Pathogenic 0.837565 1 Phe 604 A G Pathogenic 0.837565 1 Phe 604 A T Pathogenic 0.837565 1 Phe 605 T A Neutral 0.156143 0 Phe 605 T C Neutral 0.237883 0 Phe 605 T G Neutral 0.155022 0 Phe 606 A C Neutral 0.246892 1 Phe 606 A G Neutral 0.172644 0 Phe 606 A T Neutral 0.246892 1 Phe 607 C A Pathogenic 0.778582 1 Phe 607 C G Pathogenic 0.778582 1 Phe 607 C T Pathogenic 0.75434 1 Phe 608 A C Likely neutral 0.43567 1 Phe 608 A G Likely neutral 0.276875 1 Phe 608 A T Likely neutral 0.43567 1 Phe 609 C A Likely pathogenic 0.560761 1 Phe 609 C G Likely pathogenic 0.560761 1 Phe 609 C T Likely pathogenic 0.560761 1 Phe 610 T A Likely neutral 0.469432 1 Phe 610 T C Likely neutral 0.469432 1 Phe 610 T G Likely neutral 0.469432 1 Phe 611 G A Pathogenic 0.765256 1 Phe 611 G C Pathogenic 0.765256 1 Phe 611 G T Pathogenic 0.765256 1 Phe 612 A C Likely neutral 0.424786 1 Phe 612 A G Likely neutral 0.424786 1 Phe 612 A T Likely neutral 0.424786 1 Phe 613 A C Likely pathogenic 0.612803 1 Phe 613 A G Likely pathogenic 0.612803 1 Phe 613 A T Likely pathogenic 0.612803 1 Phe 614 A C Likely pathogenic 0.612803 1 Phe 614 A G Likely pathogenic 0.612803 1 Phe 614 A T Likely pathogenic 0.612803 1 Phe 615 A C Likely pathogenic 0.635665 1 Phe 615 A G Likely pathogenic 0.635665 1 Phe 615 A T Likely pathogenic 0.635665 1 Phe 616 T A Neutral 0.181048 1 Phe 616 T C Neutral 0.181048 1 Phe 616 T G Neutral 0.181048 1 Phe 617 G A Pathogenic 0.798948 1 Phe 617 G C Pathogenic 0.837125 1 Phe 617 G T Pathogenic 0.837125 1 Phe 618 T A Neutral 0.364271 1 Phe 618 T C Likely neutral 0.46917 0 Phe 618 T G Neutral 0.364271 1 Phe 619 T A Neutral 0.25076 0 Phe 619 T C Neutral 0.199734 0 Phe 619 T G Neutral 0.25076 0 Phe 620 T A Likely pathogenic 0.602285 1 Phe 620 T C Likely pathogenic 0.630461 1 Phe 620 T G Likely pathogenic 0.602285 1 Phe 621 A C Neutral 0.255186 0 Phe 621 A G Likely neutral 0.345793 0 Phe 621 A T Likely neutral 0.345793 0 Phe 622 G A Pathogenic 0.782111 1 Phe 622 G C Pathogenic 0.782111 1 Phe 622 G T Pathogenic 0.782111 1 Phe 623 A C Pathogenic 0.656308 1 Phe 623 A G Pathogenic 0.656308 1 Phe 623 A T Pathogenic 0.656308 1 Phe 624 C A Neutral 0.252311 0 Phe 624 C G Neutral 0.252311 0 Phe 624 C T Neutral 0.217176 0 Phe 625 G A Likely pathogenic 0.548018 1 Phe 625 G C Likely pathogenic 0.568285 1 Phe 625 G T Likely pathogenic 0.568285 1 Phe 626 G A Neutral 0.200042 1 Phe 626 G C Neutral 0.308243 1 Phe 626 G T Neutral 0.308243 1 Phe 627 G A Neutral 0.225987 0 Phe 627 G C Neutral 0.32629 1 Phe 627 G T Neutral 0.32629 1 Phe 628 C A Neutral 0.272936 0 Phe 628 C G Neutral 0.272936 0 Phe 628 C T Neutral 0.246571 0 Phe 629 T A Neutral 0.192636 0 Phe 629 T C Neutral 0.199467 0 Phe 629 T G Neutral 0.223463 0 Phe 630 C A Neutral 0.223899 0 Phe 630 C G Neutral 0.278085 0 Phe 630 C T Neutral 0.20873 0 Phe 631 A C Neutral 0.102452 0 Phe 631 A G Neutral 0.105082 0 Phe 631 A T Neutral 0.099479 0 Phe 632 C A Neutral 0.222078 0 Phe 632 C G Neutral 0.320369 0 Phe 632 C T Neutral 0.183188 0 Phe 633 A C Neutral 0.107531 0 Phe 633 A G Neutral 0.1084 0 Phe 633 A T Neutral 0.100583 0 Phe 634 T A Neutral 0.160546 0 Phe 634 T C Neutral 0.191668 0 Phe 634 T G Neutral 0.274671 0 Phe 635 C A Neutral 0.21772 0 Phe 635 C G Neutral 0.2159 0 Phe 635 C T Neutral 0.214093 0 Phe 636 A C Neutral 0.184812 0 Phe 636 A G Neutral 0.06472 0 Phe 636 A T Neutral 0.184812 0 Phe 637 C A Likely neutral 0.430003 1 Phe 637 C G Likely neutral 0.430003 1 Phe 637 C T Neutral 0.353329 1 Phe 638 C A Neutral 0.342454 1 Phe 638 C G Neutral 0.342454 1 Phe 638 C T Neutral 0.269293 1 Phe 639 C A Likely pathogenic 0.591149 1 Phe 639 C G Likely pathogenic 0.591149 1 Phe 639 C T Likely pathogenic 0.591149 1 Phe 640 C A Pathogenic 0.80198 1 Phe 640 C G Pathogenic 0.80198 1 Phe 640 C T Pathogenic 0.80198 1 Phe 641 A C Likely pathogenic 0.551394 1 Phe 641 A G Likely pathogenic 0.520698 1 Phe 641 A T Likely pathogenic 0.551394 1 Phe 642 T A Likely pathogenic 0.656983 1 Phe 642 T C Likely pathogenic 0.672594 1 Phe 642 T G Likely pathogenic 0.656983 1 Phe 643 A C Likely pathogenic 0.61923 0 Phe 643 A G Likely pathogenic 0.594441 1 Phe 643 A T Likely pathogenic 0.594441 0 Phe 644 A C Pathogenic 0.771652 1 Phe 644 A G Pathogenic 0.771652 1 Phe 644 A T Pathogenic 0.771652 1 Phe 645 A C Likely pathogenic 0.684357 1 Phe 645 A G Likely pathogenic 0.684357 1 Phe 645 A T Likely pathogenic 0.684357 1 Phe 646 C A Pathogenic 0.804488 1 Phe 646 C G Pathogenic 0.804488 1 Phe 646 C T Pathogenic 0.804488 1 Phe 647 A C Likely pathogenic 0.587687 1 Phe 647 A G Likely pathogenic 0.587687 1 Phe 647 A T Likely pathogenic 0.587687 1 Pro 16023 C A Pathogenic 0.804488 1 Pro 16023 C G Pathogenic 0.804488 1 Pro 16023 C T Pathogenic 0.804488 1 Pro 16022 A C Pathogenic 0.699696 1 Pro 16022 A G Pathogenic 0.699696 1 Pro 16022 A T Pathogenic 0.699696 1 Pro 16021 G A Likely pathogenic 0.550921 0 Pro 16021 G C Likely pathogenic 0.607363 1 Pro 16021 G T Likely pathogenic 0.607363 1 Pro 16020 A C Neutral 0.306886 1 Pro 16020 A G Neutral 0.257388 1 Pro 16020 A T Neutral 0.306886 1 Pro 16019 G A Likely pathogenic 0.558121 1 Pro 16019 G C Likely pathogenic 0.622458 1 Pro 16019 G T Likely pathogenic 0.622458 1 Pro 16018 A C Likely neutral 0.392214 1 Pro 16018 A G Neutral 0.313463 1 Pro 16018 A T Likely neutral 0.392214 1 Pro 16017 A C Likely neutral 0.376419 1 Pro 16017 A G Neutral 0.288671 0 Pro 16017 A T Likely neutral 0.376419 1 Pro 16016 T A Likely neutral 0.432439 1 Pro 16016 T C Likely neutral 0.432439 1 Pro 16016 T G Likely neutral 0.432439 1 Pro 16015 A C Likely neutral 0.468085 1 Pro 16015 A G Likely neutral 0.468085 1 Pro 16015 A T Likely neutral 0.468085 1 Pro 16014 G A Pathogenic 0.821014 1 Pro 16014 G C Pathogenic 0.821014 1 Pro 16014 G T Pathogenic 0.821014 1 Pro 16013 T A Likely pathogenic 0.520981 1 Pro 16013 T C Likely pathogenic 0.520981 1 Pro 16013 T G Likely pathogenic 0.520981 1 Pro 16012 T A Pathogenic 0.771386 1 Pro 16012 T C Pathogenic 0.771386 1 Pro 16012 T G Pathogenic 0.771386 1 Pro 16011 T A Likely pathogenic 0.623991 1 Pro 16011 T C Likely pathogenic 0.623991 1 Pro 16011 T G Likely pathogenic 0.623991 1 Pro 16010 A C Likely pathogenic 0.649738 1 Pro 16010 A G Likely pathogenic 0.649738 1 Pro 16010 A T Likely pathogenic 0.649738 1 Pro 16009 A C Likely pathogenic 0.575804 1 Pro 16009 A G Likely pathogenic 0.575804 1 Pro 16009 A T Likely pathogenic 0.552782 1 Pro 16008 A C Neutral 0.221562 0 Pro 16008 A G Neutral 0.145961 0 Pro 16008 A T Neutral 0.148592 0 Pro 16007 T A Neutral 0.163662 0 Pro 16007 T C Neutral 0.212018 0 Pro 16007 T G Neutral 0.212018 0 Pro 16006 T A Neutral 0.196895 1 Pro 16006 T C Neutral 0.251813 1 Pro 16006 T G Neutral 0.251813 1 Pro 16005 A C Likely neutral 0.432846 1 Pro 16005 A G Likely neutral 0.432846 1 Pro 16005 A T Likely neutral 0.432846 1 Pro 16004 G A Pathogenic 0.788703 1 Pro 16004 G C Pathogenic 0.788703 1 Pro 16004 G T Pathogenic 0.788703 1 Pro 16003 A C Likely pathogenic 0.557795 1 Pro 16003 A G Likely pathogenic 0.557795 1 Pro 16003 A T Likely pathogenic 0.557795 1 Pro 16002 A C Pathogenic 0.837565 1 Pro 16002 A G Pathogenic 0.837565 1 Pro 16002 A T Pathogenic 0.837565 1 Pro 16001 T A Neutral 0.356564 0 Pro 16001 T C Neutral 0.268998 0 Pro 16001 T G Neutral 0.356564 0 Pro 16000 C A Neutral 0.212445 0 Pro 16000 C G Neutral 0.217541 0 Pro 16000 C T Neutral 0.212259 0 Pro 15999 T A Likely neutral 0.392283 1 Pro 15999 T C Likely neutral 0.407874 1 Pro 15999 T G Likely neutral 0.392283 1 Pro 15998 T A Likely neutral 0.48986 1 Pro 15998 T C Likely neutral 0.499201 0 Pro 15998 T G Likely neutral 0.48986 1 Pro 15997 A C Likely neutral 0.407629 1 Pro 15997 A G Neutral 0.311338 1 Pro 15997 A T Likely neutral 0.407629 1 Pro 15996 G A Pathogenic 0.878552 0 Pro 15996 G C Pathogenic 0.878552 1 Pro 15996 G T Pathogenic 0.878552 1 Pro 15995 C A Likely neutral 0.481142 1 Pro 15995 C G Likely neutral 0.481142 1 Pro 15995 C T Likely neutral 0.315391 1 Pro 15994 T A Likely neutral 0.343502 1 Pro 15994 T C Likely neutral 0.343502 1 Pro 15994 T G Likely neutral 0.343502 1 Pro 15993 T A Likely pathogenic 0.527095 1 Pro 15993 T C Likely pathogenic 0.527095 1 Pro 15993 T G Likely pathogenic 0.527095 1 Pro 15992 T A Likely neutral 0.323294 1 Pro 15992 T C Likely neutral 0.323294 1 Pro 15992 T G Likely neutral 0.323294 1 Pro 15991 G A Likely pathogenic 0.558385 1 Pro 15991 G C Likely pathogenic 0.558385 1 Pro 15991 G T Likely pathogenic 0.558385 1 Pro 15990 G A Likely pathogenic 0.515245 1 Pro 15990 G C Likely pathogenic 0.515245 1 Pro 15990 G T Likely pathogenic 0.515245 1 Pro 15989 G A Pathogenic 0.694097 1 Pro 15989 G C Pathogenic 0.694097 1 Pro 15989 G T Pathogenic 0.694097 1 Pro 15988 T A Neutral 0.239421 0 Pro 15988 T C Neutral 0.307536 0 Pro 15988 T G Neutral 0.211899 0 Pro 15987 G A Neutral 0.295025 1 Pro 15987 G C Likely neutral 0.428575 1 Pro 15987 G T Likely neutral 0.428575 1 Pro 15986 C A Neutral 0.345713 1 Pro 15986 C G Neutral 0.345713 1 Pro 15986 C T Likely neutral 0.285897 0 Pro 15985 T A Likely pathogenic 0.582463 1 Pro 15985 T C Likely pathogenic 0.543018 1 Pro 15985 T G Likely pathogenic 0.582463 1 Pro 15984 A C Likely pathogenic 0.524324 1 Pro 15984 A G Likely pathogenic 0.514265 0 Pro 15984 A T Likely pathogenic 0.524324 1 Pro 15983 A C Likely neutral 0.421663 1 Pro 15983 A G Neutral 0.317868 1 Pro 15983 A T Likely neutral 0.421663 1 Pro 15982 T A Neutral 0.133719 0 Pro 15982 T C Neutral 0.128098 0 Pro 15982 T G Neutral 0.153302 0 Pro 15981 G A Likely neutral 0.476827 1 Pro 15981 G C Likely pathogenic 0.526243 1 Pro 15981 G T Likely pathogenic 0.526243 1 Pro 15980 G A Pathogenic 0.735345 1 Pro 15980 G C Pathogenic 0.735345 1 Pro 15980 G T Pathogenic 0.735345 1 Pro 15979 T A Likely neutral 0.455316 1 Pro 15979 T C Likely neutral 0.396854 1 Pro 15979 T G Likely neutral 0.455316 1 Pro 15978 G A Neutral 0.267266 0 Pro 15978 G C Likely neutral 0.387192 0 Pro 15978 G T Likely neutral 0.387192 0 Pro 15977 G A Neutral 0.305245 0 Pro 15977 G C Likely neutral 0.415014 0 Pro 15977 G T Likely neutral 0.415014 0 Pro 15976 A C Neutral 0.295544 1 Pro 15976 A G Neutral 0.197798 0 Pro 15976 A T Neutral 0.295544 1 Pro 15975 G A Pathogenic 0.759917 1 Pro 15975 G C Pathogenic 0.766298 1 Pro 15975 G T Pathogenic 0.766298 1 Pro 15974 T A Neutral 0.142166 1 Pro 15974 T C Neutral 0.151319 0 Pro 15974 T G Neutral 0.142166 1 Pro 15973 T A Neutral 0.125114 0 Pro 15973 T C Neutral 0.138998 0 Pro 15973 T G Neutral 0.138998 0 Pro 15972 A C Neutral 0.207789 0 Pro 15972 A G Neutral 0.082291 0 Pro 15972 A T Neutral 0.082592 0 Pro 15971 A C Neutral 0.229296 0 Pro 15971 A G Neutral 0.189671 0 Pro 15971 A T Neutral 0.206372 0 Pro 15970 A C Neutral 0.203956 0 Pro 15970 A G Neutral 0.159716 0 Pro 15970 A T Neutral 0.153284 0 Pro 15969 G A Neutral 0.299221 0 Pro 15969 G C Likely neutral 0.41347 0 Pro 15969 G T Neutral 0.296352 0 Pro 15968 A C Neutral 0.18779 1 Pro 15968 A G Neutral 0.132339 0 Pro 15968 A T Neutral 0.145471 1 Pro 15967 C A Likely neutral 0.487125 1 Pro 15967 C G Likely pathogenic 0.517278 1 Pro 15967 C T Likely pathogenic 0.501139 1 Pro 15966 T A Neutral 0.361244 1 Pro 15966 T C Likely neutral 0.363815 0 Pro 15966 T G Neutral 0.361244 1 Pro 15965 T A Neutral 0.333901 0 Pro 15965 T C Neutral 0.196999 0 Pro 15965 T G Neutral 0.333901 0 Pro 15964 T A Neutral 0.247666 0 Pro 15964 T C Neutral 0.162178 0 Pro 15964 T G Neutral 0.247666 0 Pro 15963 T A Neutral 0.350776 1 Pro 15963 T C Neutral 0.281494 0 Pro 15963 T G Neutral 0.350776 1 Pro 15962 T A Likely pathogenic 0.50065 1 Pro 15962 T C Likely pathogenic 0.50065 1 Pro 15962 T G Likely pathogenic 0.50065 1 Pro 15961 C A Likely pathogenic 0.515278 1 Pro 15961 C G Likely pathogenic 0.515278 1 Pro 15961 C T Likely neutral 0.474966 1 Pro 15960 T A Neutral 0.365159 1 Pro 15960 T C Neutral 0.283934 1 Pro 15960 T G Neutral 0.365159 1 Pro 15959 C A Likely pathogenic 0.520887 1 Pro 15959 C G Likely pathogenic 0.520887 1 Pro 15959 C T Likely neutral 0.498547 0 Pro 15958 T A Likely pathogenic 0.618852 1 Pro 15958 T C Likely pathogenic 0.618852 1 Pro 15958 T G Likely pathogenic 0.618852 1 Pro 15957 G A Pathogenic 0.812523 1 Pro 15957 G C Pathogenic 0.812523 1 Pro 15957 G T Pathogenic 0.741802 1 Pro 15956 A C Likely neutral 0.492092 1 Pro 15956 A G Likely neutral 0.450289 1 Pro 15956 A T Likely neutral 0.492092 1 Ser(AGY) 12207 G A Neutral 0.238865 0 Ser(AGY) 12207 G C Neutral 0.364151 1 Ser(AGY) 12207 G T Neutral 0.364151 1 Ser(AGY) 12208 A C Likely neutral 0.482572 1 Ser(AGY) 12208 A G Likely neutral 0.405666 1 Ser(AGY) 12208 A T Likely neutral 0.482572 1 Ser(AGY) 12209 G A Pathogenic 0.894294 1 Ser(AGY) 12209 G C Pathogenic 0.894294 1 Ser(AGY) 12209 G T Pathogenic 0.894294 1 Ser(AGY) 12210 A C Likely neutral 0.393671 1 Ser(AGY) 12210 A G Likely neutral 0.32814 1 Ser(AGY) 12210 A T Likely neutral 0.393671 1 Ser(AGY) 12211 A C Pathogenic 0.771652 1 Ser(AGY) 12211 A G Pathogenic 0.771652 1 Ser(AGY) 12211 A T Pathogenic 0.771652 1 Ser(AGY) 12212 A C Likely neutral 0.372555 1 Ser(AGY) 12212 A G Likely neutral 0.372555 1 Ser(AGY) 12212 A T Neutral 0.314936 1 Ser(AGY) 12213 G A Likely pathogenic 0.5389 1 Ser(AGY) 12213 G C Pathogenic 0.660855 1 Ser(AGY) 12213 G T Pathogenic 0.660855 1 Ser(AGY) 12214 C A Neutral 0.131326 0 Ser(AGY) 12214 C G Neutral 0.252503 0 Ser(AGY) 12214 C T Neutral 0.155197 0 Ser(AGY) 12215 T A Neutral 0.173214 0 Ser(AGY) 12215 T C Neutral 0.173538 0 Ser(AGY) 12215 T G Neutral 0.286658 0 Ser(AGY) 12216 C A Neutral 0.261142 0 Ser(AGY) 12216 C G Neutral 0.283541 0 Ser(AGY) 12216 C T Neutral 0.241949 0 Ser(AGY) 12217 A C Neutral 0.158749 0 Ser(AGY) 12217 A G Neutral 0.134276 0 Ser(AGY) 12217 A T Neutral 0.158749 0 Ser(AGY) 12218 C A Likely pathogenic 0.563629 1 Ser(AGY) 12218 C G Likely pathogenic 0.591088 1 Ser(AGY) 12218 C T Likely pathogenic 0.522243 0 Ser(AGY) 12219 A C Likely pathogenic 0.60524 1 Ser(AGY) 12219 A G Likely pathogenic 0.60524 0 Ser(AGY) 12219 A T Likely pathogenic 0.516085 1 Ser(AGY) 12220 A C Neutral 0.305971 0 Ser(AGY) 12220 A G Neutral 0.255746 0 Ser(AGY) 12220 A T Neutral 0.255746 0 Ser(AGY) 12221 G A Pathogenic 0.894294 1 Ser(AGY) 12221 G C Pathogenic 0.894294 1 Ser(AGY) 12221 G T Pathogenic 0.894294 1 Ser(AGY) 12222 A C Likely neutral 0.393671 1 Ser(AGY) 12222 A G Likely neutral 0.32814 1 Ser(AGY) 12222 A T Likely neutral 0.393671 1 Ser(AGY) 12223 A C Likely pathogenic 0.508148 1 Ser(AGY) 12223 A G Likely neutral 0.430503 1 Ser(AGY) 12223 A T Likely pathogenic 0.508148 1 Ser(AGY) 12224 C A Likely neutral 0.423069 1 Ser(AGY) 12224 C G Likely neutral 0.423069 1 Ser(AGY) 12224 C T Likely neutral 0.349899 1 Ser(AGY) 12225 T A Likely neutral 0.436455 1 Ser(AGY) 12225 T C Likely neutral 0.421519 1 Ser(AGY) 12225 T G Likely neutral 0.436455 1 Ser(AGY) 12226 G A Likely pathogenic 0.508705 1 Ser(AGY) 12226 G C Likely pathogenic 0.508705 1 Ser(AGY) 12226 G T Likely pathogenic 0.508705 1 Ser(AGY) 12227 C A Likely pathogenic 0.619777 1 Ser(AGY) 12227 C G Likely pathogenic 0.619777 1 Ser(AGY) 12227 C T Likely pathogenic 0.619777 1 Ser(AGY) 12228 T A Likely neutral 0.487859 1 Ser(AGY) 12228 T C Likely neutral 0.487859 1 Ser(AGY) 12228 T G Likely neutral 0.487859 1 Ser(AGY) 12229 A C Likely pathogenic 0.613322 1 Ser(AGY) 12229 A G Likely pathogenic 0.613322 1 Ser(AGY) 12229 A T Likely pathogenic 0.613322 1 Ser(AGY) 12230 A C Likely pathogenic 0.632571 1 Ser(AGY) 12230 A G Likely pathogenic 0.632571 1 Ser(AGY) 12230 A T Likely pathogenic 0.632571 1 Ser(AGY) 12231 C A Neutral 0.360071 0 Ser(AGY) 12231 C G Neutral 0.360071 0 Ser(AGY) 12231 C T Likely neutral 0.330221 0 Ser(AGY) 12232 T A Likely pathogenic 0.532339 1 Ser(AGY) 12232 T C Likely neutral 0.422117 1 Ser(AGY) 12232 T G Likely pathogenic 0.532339 1 Ser(AGY) 12233 C A Pathogenic 0.88991 1 Ser(AGY) 12233 C G Pathogenic 0.88991 1 Ser(AGY) 12233 C T Pathogenic 0.88991 1 Ser(AGY) 12234 A C Neutral 0.11384 0 Ser(AGY) 12234 A G Neutral 0.136307 0 Ser(AGY) 12234 A T Neutral 0.117237 0 Ser(AGY) 12235 T A Likely neutral 0.371949 1 Ser(AGY) 12235 T C Neutral 0.309559 0 Ser(AGY) 12235 T G Likely neutral 0.371949 1 Ser(AGY) 12236 G A Neutral 0.087948 0 Ser(AGY) 12236 G C Neutral 0.100071 1 Ser(AGY) 12236 G T Neutral 0.163801 1 Ser(AGY) 12237 C A Neutral 0.182701 0 Ser(AGY) 12237 C G Neutral 0.280952 0 Ser(AGY) 12237 C T Neutral 0.185733 0 Ser(AGY) 12238 C A Neutral 0.126175 0 Ser(AGY) 12238 C G Neutral 0.242866 0 Ser(AGY) 12238 C T Neutral 0.134527 0 Ser(AGY) 12239 C A Neutral 0.127735 0 Ser(AGY) 12239 C G Neutral 0.24343 0 Ser(AGY) 12239 C T Neutral 0.138405 0 Ser(AGY) 12240 C A Likely pathogenic 0.560995 1 Ser(AGY) 12240 C G Likely pathogenic 0.560995 1 Ser(AGY) 12240 C T Likely pathogenic 0.535207 1 Ser(AGY) 12241 C A Pathogenic 0.732438 1 Ser(AGY) 12241 C G Pathogenic 0.732438 1 Ser(AGY) 12241 C T Pathogenic 0.684383 1 Ser(AGY) 12242 A C Neutral 0.242218 1 Ser(AGY) 12242 A G Neutral 0.16925 1 Ser(AGY) 12242 A T Neutral 0.242218 1 Ser(AGY) 12243 T A Neutral 0.322339 1 Ser(AGY) 12243 T C Likely neutral 0.326522 1 Ser(AGY) 12243 T G Likely neutral 0.360093 1 Ser(AGY) 12244 G A Likely neutral 0.362426 0 Ser(AGY) 12244 G C Likely neutral 0.433774 1 Ser(AGY) 12244 G T Likely neutral 0.433774 1 Ser(AGY) 12245 T A Neutral 0.152705 0 Ser(AGY) 12245 T C Neutral 0.15178 0 Ser(AGY) 12245 T G Neutral 0.275343 0 Ser(AGY) 12246 C A Neutral 0.177953 0 Ser(AGY) 12246 C G Neutral 0.223301 0 Ser(AGY) 12246 C T Neutral 0.186961 0 Ser(AGY) 12247 T A Likely neutral 0.487859 1 Ser(AGY) 12247 T C Likely neutral 0.487859 1 Ser(AGY) 12247 T G Likely neutral 0.487859 1 Ser(AGY) 12248 A C Likely pathogenic 0.649738 1 Ser(AGY) 12248 A G Likely pathogenic 0.649738 1 Ser(AGY) 12248 A T Likely pathogenic 0.649738 1 Ser(AGY) 12249 A C Likely pathogenic 0.533011 1 Ser(AGY) 12249 A G Likely pathogenic 0.601547 1 Ser(AGY) 12249 A T Likely pathogenic 0.601547 1 Ser(AGY) 12250 C A Neutral 0.181582 0 Ser(AGY) 12250 C G Neutral 0.284573 0 Ser(AGY) 12250 C T Neutral 0.15319 0 Ser(AGY) 12251 A C Likely neutral 0.333518 1 Ser(AGY) 12251 A G Likely neutral 0.42701 1 Ser(AGY) 12251 A T Likely neutral 0.42701 1 Ser(AGY) 12252 A C Neutral 0.12811 0 Ser(AGY) 12252 A G Neutral 0.141112 0 Ser(AGY) 12252 A T Neutral 0.12811 0 Ser(AGY) 12253 C A Likely neutral 0.357078 1 Ser(AGY) 12253 C G Likely neutral 0.426851 1 Ser(AGY) 12253 C T Likely neutral 0.345529 0 Ser(AGY) 12254 A C Likely neutral 0.43777 1 Ser(AGY) 12254 A G Likely neutral 0.410261 1 Ser(AGY) 12254 A T Likely neutral 0.467216 1 Ser(AGY) 12255 T A Neutral 0.272806 1 Ser(AGY) 12255 T C Neutral 0.252193 1 Ser(AGY) 12255 T G Neutral 0.272806 1 Ser(AGY) 12256 G A Likely pathogenic 0.632613 1 Ser(AGY) 12256 G C Pathogenic 0.683754 1 Ser(AGY) 12256 G T Pathogenic 0.683754 1 Ser(AGY) 12257 G A Likely pathogenic 0.564315 1 Ser(AGY) 12257 G C Likely pathogenic 0.596014 1 Ser(AGY) 12257 G T Likely pathogenic 0.596014 1 Ser(AGY) 12258 C A Likely pathogenic 0.680846 1 Ser(AGY) 12258 C G Likely pathogenic 0.680846 1 Ser(AGY) 12258 C T Likely pathogenic 0.565164 1 Ser(AGY) 12259 T A Likely pathogenic 0.520496 1 Ser(AGY) 12259 T C Likely pathogenic 0.506145 1 Ser(AGY) 12259 T G Likely pathogenic 0.520496 1 Ser(AGY) 12260 T A Likely neutral 0.457893 1 Ser(AGY) 12260 T C Likely neutral 0.457893 1 Ser(AGY) 12260 T G Likely pathogenic 0.528451 1 Ser(AGY) 12261 T A Likely neutral 0.408271 1 Ser(AGY) 12261 T C Neutral 0.296156 1 Ser(AGY) 12261 T G Likely neutral 0.408271 1 Ser(AGY) 12262 C A Pathogenic 0.872772 1 Ser(AGY) 12262 C G Pathogenic 0.872772 1 Ser(AGY) 12262 C T Pathogenic 0.872772 1 Ser(AGY) 12263 T A Likely pathogenic 0.535079 1 Ser(AGY) 12263 T C Likely neutral 0.414109 1 Ser(AGY) 12263 T G Likely pathogenic 0.535079 1 Ser(AGY) 12264 C A Likely neutral 0.445438 1 Ser(AGY) 12264 C G Likely neutral 0.445438 1 Ser(AGY) 12264 C T Likely neutral 0.345831 0 Ser(AGY) 12265 A C Likely neutral 0.469398 NA Ser(AGY) 12265 A G Likely neutral 0.396023 NA Ser(AGY) 12265 A T Likely neutral 0.469398 NA Ser(UCN) 7514 G A Likely neutral 0.358036 0 Ser(UCN) 7514 G C Likely neutral 0.471184 0 Ser(UCN) 7514 G T Likely neutral 0.471184 0 Ser(UCN) 7513 A C Likely neutral 0.363778 1 Ser(UCN) 7513 A G Neutral 0.27138 1 Ser(UCN) 7513 A T Likely neutral 0.363778 1 Ser(UCN) 7512 A C Likely neutral 0.427673 1 Ser(UCN) 7512 A G Likely neutral 0.427217 1 Ser(UCN) 7512 A T Likely neutral 0.427673 1 Ser(UCN) 7511 A C Pathogenic 0.771652 1 Ser(UCN) 7511 A G Pathogenic 0.771652 1 Ser(UCN) 7511 A T Pathogenic 0.771652 1 Ser(UCN) 7510 A C Likely pathogenic 0.650529 1 Ser(UCN) 7510 A G Likely pathogenic 0.567912 0 Ser(UCN) 7510 A T Likely pathogenic 0.650529 1 Ser(UCN) 7509 A C Neutral 0.327324 1 Ser(UCN) 7509 A G Neutral 0.249866 1 Ser(UCN) 7509 A T Neutral 0.327324 1 Ser(UCN) 7508 G A Pathogenic 0.879617 1 Ser(UCN) 7508 G C Pathogenic 0.897808 1 Ser(UCN) 7508 G T Pathogenic 0.897808 1 Ser(UCN) 7507 T A Likely neutral 0.399471 1 Ser(UCN) 7507 T C Likely neutral 0.488581 1 Ser(UCN) 7507 T G Likely neutral 0.488581 1 Ser(UCN) 7506 C A Pathogenic 0.645334 1 Ser(UCN) 7506 C G Pathogenic 0.645334 1 Ser(UCN) 7506 C T Likely pathogenic 0.587697 1 Ser(UCN) 7505 A C Likely pathogenic 0.525514 1 Ser(UCN) 7505 A G Likely neutral 0.464196 1 Ser(UCN) 7505 A T Likely pathogenic 0.525514 1 Ser(UCN) 7504 T A Neutral 0.181048 1 Ser(UCN) 7504 T C Neutral 0.181048 1 Ser(UCN) 7504 T G Neutral 0.181048 1 Ser(UCN) 7503 G A Likely neutral 0.438424 0 Ser(UCN) 7503 G C Likely neutral 0.429994 1 Ser(UCN) 7503 G T Likely neutral 0.429994 1 Ser(UCN) 7502 G A Neutral 0.111081 0 Ser(UCN) 7502 G C Neutral 0.258936 1 Ser(UCN) 7502 G T Neutral 0.121719 1 Ser(UCN) 7501 A C Neutral 0.279432 0 Ser(UCN) 7501 A G Neutral 0.154138 0 Ser(UCN) 7501 A T Neutral 0.152683 0 Ser(UCN) 7500 G A Likely neutral 0.467531 1 Ser(UCN) 7500 G C Likely neutral 0.467531 1 Ser(UCN) 7500 G T Likely neutral 0.467531 1 Ser(UCN) 7499 G A Likely neutral 0.463125 1 Ser(UCN) 7499 G C Likely neutral 0.463125 1 Ser(UCN) 7499 G T Likely neutral 0.437557 1 Ser(UCN) 7498 C A Neutral 0.094459 0 Ser(UCN) 7498 C G Neutral 0.195308 0 Ser(UCN) 7498 C T Neutral 0.116729 0 Ser(UCN) 7497 C A Likely pathogenic 0.507597 1 Ser(UCN) 7497 C G Likely pathogenic 0.507597 1 Ser(UCN) 7497 C T Likely pathogenic 0.57753 0 Ser(UCN) 7496 A C Likely pathogenic 0.600502 1 Ser(UCN) 7496 A G Likely pathogenic 0.568997 1 Ser(UCN) 7496 A T Likely pathogenic 0.600502 1 Ser(UCN) 7495 T A Likely neutral 0.371533 1 Ser(UCN) 7495 T C Likely neutral 0.402134 1 Ser(UCN) 7495 T G Likely neutral 0.371533 1 Ser(UCN) 7494 G A Likely neutral 0.383438 1 Ser(UCN) 7494 G C Likely neutral 0.487427 1 Ser(UCN) 7494 G T Likely neutral 0.487427 1 Ser(UCN) 7493 G A Neutral 0.134482 0 Ser(UCN) 7493 G C Neutral 0.156925 0 Ser(UCN) 7493 G T Neutral 0.156925 0 Ser(UCN) 7492 G A Neutral 0.158634 1 Ser(UCN) 7492 G C Neutral 0.253827 1 Ser(UCN) 7492 G T Neutral 0.157042 1 Ser(UCN) 7491 G A Likely pathogenic 0.509586 0 Ser(UCN) 7491 G C Likely pathogenic 0.601204 1 Ser(UCN) 7491 G T Likely pathogenic 0.601204 1 Ser(UCN) 7490 T A Neutral 0.237657 0 Ser(UCN) 7490 T C Neutral 0.22979 0 Ser(UCN) 7490 T G Neutral 0.237657 0 Ser(UCN) 7489 T A Likely neutral 0.456958 1 Ser(UCN) 7489 T C Likely neutral 0.456958 1 Ser(UCN) 7489 T G Likely neutral 0.456958 1 Ser(UCN) 7488 G A Pathogenic 0.788893 1 Ser(UCN) 7488 G C Pathogenic 0.788893 1 Ser(UCN) 7488 G T Pathogenic 0.788893 1 Ser(UCN) 7487 G A Likely pathogenic 0.609572 1 Ser(UCN) 7487 G C Likely pathogenic 0.609572 1 Ser(UCN) 7487 G T Likely pathogenic 0.609572 1 Ser(UCN) 7486 C A Likely pathogenic 0.619777 1 Ser(UCN) 7486 C G Likely pathogenic 0.619777 1 Ser(UCN) 7486 C T Likely pathogenic 0.619777 1 Ser(UCN) 7485 T A Likely neutral 0.343502 1 Ser(UCN) 7485 T C Likely neutral 0.343502 1 Ser(UCN) 7485 T G Likely neutral 0.343502 1 Ser(UCN) 7484 T A Likely neutral 0.323294 1 Ser(UCN) 7484 T C Likely neutral 0.323294 1 Ser(UCN) 7484 T G Likely neutral 0.323294 1 Ser(UCN) 7483 G A Pathogenic 0.765256 1 Ser(UCN) 7483 G C Pathogenic 0.765256 1 Ser(UCN) 7483 G T Pathogenic 0.765256 1 Ser(UCN) 7482 A C Likely neutral 0.424786 1 Ser(UCN) 7482 A G Likely neutral 0.424786 1 Ser(UCN) 7482 A T Likely neutral 0.424786 1 Ser(UCN) 7481 A C Likely pathogenic 0.612803 1 Ser(UCN) 7481 A G Likely pathogenic 0.612803 1 Ser(UCN) 7481 A T Likely pathogenic 0.612803 1 Ser(UCN) 7480 A C Likely pathogenic 0.632571 1 Ser(UCN) 7480 A G Likely pathogenic 0.632571 1 Ser(UCN) 7480 A T Likely pathogenic 0.632571 1 Ser(UCN) 7479 C A Pathogenic 0.674612 1 Ser(UCN) 7479 C G Pathogenic 0.674612 1 Ser(UCN) 7479 C T Pathogenic 0.674612 1 Ser(UCN) 7478 C A Likely pathogenic 0.539477 1 Ser(UCN) 7478 C G Likely pathogenic 0.539477 1 Ser(UCN) 7478 C T Likely neutral 0.376789 1 Ser(UCN) 7477 A C Likely pathogenic 0.62625 1 Ser(UCN) 7477 A G Likely pathogenic 0.579156 1 Ser(UCN) 7477 A T Likely pathogenic 0.62625 1 Ser(UCN) 7476 G A Neutral 0.24235 0 Ser(UCN) 7476 G C Likely neutral 0.377072 0 Ser(UCN) 7476 G T Neutral 0.319611 0 Ser(UCN) 7475 C A Likely neutral 0.413198 1 Ser(UCN) 7475 C G Likely neutral 0.413198 1 Ser(UCN) 7475 C T Likely neutral 0.438658 0 Ser(UCN) 7474 T A Likely neutral 0.374825 1 Ser(UCN) 7474 T C Likely neutral 0.326299 1 Ser(UCN) 7474 T G Likely neutral 0.360619 1 Ser(UCN) 7473 T A Neutral 0.307664 1 Ser(UCN) 7473 T C Likely neutral 0.37221 1 Ser(UCN) 7473 T G Likely neutral 0.37221 1 Ser(UCN) 7472 T A Likely neutral 0.288846 1 Ser(UCN) 7472 T C Likely neutral 0.245297 1 Ser(UCN) 7472 T G Likely neutral 0.391973 1 Ser(UCN) 7471 G A Neutral 0.15503 0 Ser(UCN) 7471 G C Neutral 0.218392 0 Ser(UCN) 7471 G T Neutral 0.108031 0 Ser(UCN) 7470 G A Likely pathogenic 0.630322 1 Ser(UCN) 7470 G C Likely pathogenic 0.630322 1 Ser(UCN) 7470 G T Likely pathogenic 0.630322 1 Ser(UCN) 7469 G A Neutral 0.21291 0 Ser(UCN) 7469 G C Neutral 0.334834 0 Ser(UCN) 7469 G T Neutral 0.334834 0 Ser(UCN) 7468 G A Neutral 0.273838 0 Ser(UCN) 7468 G C Neutral 0.350133 0 Ser(UCN) 7468 G T Neutral 0.350133 0 Ser(UCN) 7467 G A Likely neutral 0.485138 1 Ser(UCN) 7467 G C Likely pathogenic 0.550972 1 Ser(UCN) 7467 G T Likely pathogenic 0.550972 1 Ser(UCN) 7466 G A Pathogenic 0.90568 1 Ser(UCN) 7466 G C Pathogenic 0.90568 1 Ser(UCN) 7466 G T Pathogenic 0.90568 1 Ser(UCN) 7465 T A Likely neutral 0.404409 1 Ser(UCN) 7465 T C Likely neutral 0.404409 1 Ser(UCN) 7465 T G Likely neutral 0.404409 1 Ser(UCN) 7464 T A Likely neutral 0.429305 1 Ser(UCN) 7464 T C Likely neutral 0.429305 1 Ser(UCN) 7464 T G Likely neutral 0.429305 1 Ser(UCN) 7463 C A Likely pathogenic 0.538927 1 Ser(UCN) 7463 C G Likely pathogenic 0.538927 1 Ser(UCN) 7463 C T Likely pathogenic 0.538927 1 Ser(UCN) 7462 G A Neutral 0.333989 0 Ser(UCN) 7462 G C Likely neutral 0.470235 0 Ser(UCN) 7462 G T Likely neutral 0.470235 0 Ser(UCN) 7461 A C Likely pathogenic 0.612609 1 Ser(UCN) 7461 A G Likely pathogenic 0.612609 1 Ser(UCN) 7461 A T Likely pathogenic 0.612609 1 Ser(UCN) 7460 T A Neutral 0.203413 0 Ser(UCN) 7460 T C Neutral 0.178472 0 Ser(UCN) 7460 T G Neutral 0.219961 0 Ser(UCN) 7459 T A Likely neutral 0.375079 1 Ser(UCN) 7459 T C Likely neutral 0.375079 1 Ser(UCN) 7459 T G Likely neutral 0.375079 1 Ser(UCN) 7458 C A Pathogenic 0.71995 1 Ser(UCN) 7458 C G Pathogenic 0.71995 1 Ser(UCN) 7458 C T Pathogenic 0.71995 1 Ser(UCN) 7457 C A Pathogenic 0.696834 1 Ser(UCN) 7457 C G Pathogenic 0.696834 1 Ser(UCN) 7457 C T Likely pathogenic 0.617531 1 Ser(UCN) 7456 T A Neutral 0.304551 1 Ser(UCN) 7456 T C Neutral 0.248974 1 Ser(UCN) 7456 T G Neutral 0.304551 1 Ser(UCN) 7455 T A Likely neutral 0.410004 0 Ser(UCN) 7455 T C Likely neutral 0.400273 0 Ser(UCN) 7455 T G Likely neutral 0.410004 0 Ser(UCN) 7454 C A Pathogenic 0.71995 1 Ser(UCN) 7454 C G Pathogenic 0.71995 1 Ser(UCN) 7454 C T Pathogenic 0.71995 1 Ser(UCN) 7453 C A Pathogenic 0.773437 1 Ser(UCN) 7453 C G Pathogenic 0.773437 1 Ser(UCN) 7453 C T Pathogenic 0.773437 1 Ser(UCN) 7452 T A Likely pathogenic 0.528246 1 Ser(UCN) 7452 T C Likely pathogenic 0.528246 1 Ser(UCN) 7452 T G Likely pathogenic 0.528246 1 Ser(UCN) 7451 T A Pathogenic 0.71886 1 Ser(UCN) 7451 T C Pathogenic 0.698648 0 Ser(UCN) 7451 T G Pathogenic 0.71886 1 Ser(UCN) 7450 T A Pathogenic 0.771386 1 Ser(UCN) 7450 T C Pathogenic 0.771386 1 Ser(UCN) 7450 T G Pathogenic 0.771386 1 Ser(UCN) 7449 T A Neutral 0.344527 1 Ser(UCN) 7449 T C Neutral 0.280758 1 Ser(UCN) 7449 T G Neutral 0.344527 1 Ser(UCN) 7448 T A Pathogenic 0.771386 1 Ser(UCN) 7448 T C Pathogenic 0.771386 1 Ser(UCN) 7448 T G Pathogenic 0.771386 1 Ser(UCN) 7447 T A Likely neutral 0.349145 0 Ser(UCN) 7447 T C Neutral 0.216578 0 Ser(UCN) 7447 T G Likely neutral 0.349145 0 Ser(UCN) 7446 G A Likely neutral 0.362193 1 Ser(UCN) 7446 G C Likely neutral 0.448222 1 Ser(UCN) 7446 G T Likely neutral 0.448222 1 Thr 15888 G A Pathogenic 0.899313 1 Thr 15888 G C Pathogenic 0.899313 1 Thr 15888 G T Pathogenic 0.899313 1 Thr 15889 T A Neutral 0.307251 1 Thr 15889 T C Neutral 0.229341 0 Thr 15889 T G Neutral 0.307251 1 Thr 15890 C A Likely pathogenic 0.638697 1 Thr 15890 C G Likely pathogenic 0.638697 1 Thr 15890 C T Likely pathogenic 0.60705 1 Thr 15891 C A Likely pathogenic 0.542213 1 Thr 15891 C G Likely pathogenic 0.542213 1 Thr 15891 C T Likely neutral 0.418548 1 Thr 15892 T A Neutral 0.300453 0 Thr 15892 T C Neutral 0.318162 0 Thr 15892 T G Neutral 0.317873 1 Thr 15893 T A Neutral 0.14236 0 Thr 15893 T C Neutral 0.146551 0 Thr 15893 T G Neutral 0.145422 0 Thr 15894 G A Likely pathogenic 0.569774 1 Thr 15894 G C Pathogenic 0.652696 1 Thr 15894 G T Pathogenic 0.652696 1 Thr 15895 T A Likely neutral 0.482597 1 Thr 15895 T C Likely neutral 0.482597 1 Thr 15895 T G Likely neutral 0.482597 1 Thr 15896 A C Likely neutral 0.468085 1 Thr 15896 A G Likely neutral 0.468085 1 Thr 15896 A T Likely neutral 0.468085 1 Thr 15897 G A Pathogenic 0.886803 1 Thr 15897 G C Pathogenic 0.907099 1 Thr 15897 G T Pathogenic 0.907099 1 Thr 15898 T A Likely pathogenic 0.561343 1 Thr 15898 T C Likely pathogenic 0.561343 1 Thr 15898 T G Likely pathogenic 0.561343 1 Thr 15899 A C Pathogenic 0.78682 1 Thr 15899 A G Pathogenic 0.78682 1 Thr 15899 A T Pathogenic 0.78682 1 Thr 15900 T A Likely pathogenic 0.526134 0 Thr 15900 T C Likely neutral 0.465269 0 Thr 15900 T G Likely pathogenic 0.526134 1 Thr 15901 A C Likely pathogenic 0.649738 1 Thr 15901 A G Likely pathogenic 0.649738 1 Thr 15901 A T Likely pathogenic 0.649738 1 Thr 15902 A C Likely neutral 0.427934 0 Thr 15902 A G Likely neutral 0.416528 0 Thr 15902 A T Likely neutral 0.427934 0 Thr 15903 A C Neutral 0.107571 0 Thr 15903 A G Neutral 0.112074 0 Thr 15903 A T Likely neutral 0.309719 0 Thr 15904 C A Neutral 0.225513 0 Thr 15904 C G Neutral 0.290941 0 Thr 15904 C T Neutral 0.189618 0 Thr 15905 T A Neutral 0.118337 0 Thr 15905 T C Neutral 0.122583 0 Thr 15905 T G Neutral 0.224411 0 Thr 15906 A C Likely neutral 0.4657 1 Thr 15906 A G Likely neutral 0.4657 1 Thr 15906 A T Likely neutral 0.4657 1 Thr 15907 A C Neutral 0.340803 1 Thr 15907 A G Neutral 0.232561 0 Thr 15907 A T Neutral 0.24177 0 Thr 15908 T A Likely pathogenic 0.500021 1 Thr 15908 T C Likely pathogenic 0.500021 1 Thr 15908 T G Likely pathogenic 0.500021 1 Thr 15909 A C Likely neutral 0.482315 1 Thr 15909 A G Likely neutral 0.482315 1 Thr 15909 A T Likely neutral 0.482315 1 Thr 15910 C A Pathogenic 0.650833 1 Thr 15910 C G Pathogenic 0.650833 1 Thr 15910 C T Likely pathogenic 0.550419 1 Thr 15911 A C Neutral 0.105751 0 Thr 15911 A G Neutral 0.129018 0 Thr 15911 A T Neutral 0.105655 0 Thr 15912 C A Likely neutral 0.418381 1 Thr 15912 C G Likely neutral 0.418381 1 Thr 15912 C T Neutral 0.298175 0 Thr 15913 C A Neutral 0.287904 1 Thr 15913 C G Neutral 0.343792 1 Thr 15913 C T Neutral 0.277398 1 Thr 15914 A C Neutral 0.350651 0 Thr 15914 A G Neutral 0.360233 0 Thr 15914 A T Neutral 0.350651 0 Thr 15915 G A Pathogenic 0.934854 1 Thr 15915 G C Pathogenic 0.934854 1 Thr 15915 G T Pathogenic 0.934854 1 Thr 15916 T A Likely neutral 0.482502 1 Thr 15916 T C Likely neutral 0.333705 0 Thr 15916 T G Likely neutral 0.482502 1 Thr 15917 C A Pathogenic 0.699895 1 Thr 15917 C G Pathogenic 0.699895 1 Thr 15917 C T Pathogenic 0.699895 1 Thr 15918 T A Likely neutral 0.343502 1 Thr 15918 T C Likely neutral 0.343502 1 Thr 15918 T G Likely neutral 0.343502 1 Thr 15919 T A Likely neutral 0.323294 1 Thr 15919 T C Likely neutral 0.323294 1 Thr 15919 T G Likely neutral 0.323294 1 Thr 15920 G A Pathogenic 0.71321 1 Thr 15920 G C Pathogenic 0.71321 1 Thr 15920 G T Pathogenic 0.71321 1 Thr 15921 T A Likely neutral 0.392006 1 Thr 15921 T C Likely neutral 0.392006 1 Thr 15921 T G Likely neutral 0.392006 1 Thr 15922 A C Likely pathogenic 0.613322 1 Thr 15922 A G Likely pathogenic 0.613322 1 Thr 15922 A T Likely pathogenic 0.613322 1 Thr 15923 A C Likely pathogenic 0.612803 1 Thr 15923 A G Likely pathogenic 0.612803 1 Thr 15923 A T Likely pathogenic 0.612803 1 Thr 15924 A C Likely neutral 0.336399 1 Thr 15924 A G Likely neutral 0.284635 0 Thr 15924 A T Likely neutral 0.456602 1 Thr 15925 C A Pathogenic 0.674612 1 Thr 15925 C G Pathogenic 0.674612 1 Thr 15925 C T Pathogenic 0.674612 1 Thr 15926 C A Neutral 0.314404 1 Thr 15926 C G Neutral 0.314404 1 Thr 15926 C T Neutral 0.235253 1 Thr 15927 G A Neutral 0.112642 1 Thr 15927 G C Neutral 0.21902 1 Thr 15927 G T Neutral 0.115085 1 Thr 15928 G A Neutral 0.192205 0 Thr 15928 G C Neutral 0.342514 1 Thr 15928 G T Neutral 0.342514 1 Thr 15929 A C Neutral 0.340695 1 Thr 15929 A G Neutral 0.340695 1 Thr 15929 A T Neutral 0.340695 1 Thr 15930 G A Likely pathogenic 0.544642 0 Thr 15930 G C Likely pathogenic 0.521249 0 Thr 15930 G T Likely pathogenic 0.556957 0 Thr 15931 A C Likely pathogenic 0.515854 1 Thr 15931 A G Likely pathogenic 0.558998 1 Thr 15931 A T Likely pathogenic 0.558998 1 Thr 15932 T A Neutral 0.19673 0 Thr 15932 T C Neutral 0.178202 0 Thr 15932 T G Neutral 0.251819 0 Thr 15933 G A Pathogenic 0.917206 1 Thr 15933 G C Pathogenic 0.917206 1 Thr 15933 G T Pathogenic 0.917206 1 Thr 15934 A C Neutral 0.248284 1 Thr 15934 A G Neutral 0.17629 1 Thr 15934 A T Neutral 0.248284 1 Thr 15935 A C Likely pathogenic 0.536265 1 Thr 15935 A G Likely neutral 0.453959 1 Thr 15935 A T Likely pathogenic 0.536265 1 Thr 15936 A C Likely neutral 0.353345 1 Thr 15936 A G Likely neutral 0.37957 0 Thr 15936 A T Likely neutral 0.403725 1 Thr 15937 A C Neutral 0.193993 0 Thr 15937 A G Neutral 0.167704 0 Thr 15937 A T Neutral 0.167704 0 Thr 15938 C A Neutral 0.105726 0 Thr 15938 C G Neutral 0.111076 0 Thr 15938 C T Neutral 0.108191 0 Thr 15939 C A Neutral 0.143245 0 Thr 15939 C G Neutral 0.147112 0 Thr 15939 C T Neutral 0.139607 0 Thr 15940 T A Neutral 0.124797 0 Thr 15940 T C Neutral 0.141223 0 Thr 15940 T G Neutral 0.198859 0 Thr 15941 T A Neutral 0.213742 0 Thr 15941 T C Neutral 0.215017 0 Thr 15941 T G Neutral 0.279332 0 Thr 15942 T A Neutral 0.255196 1 Thr 15942 T C Likely neutral 0.273136 0 Thr 15942 T G Neutral 0.322178 1 Thr 15943 T A Likely neutral 0.457893 1 Thr 15943 T C Likely neutral 0.457893 1 Thr 15943 T G Likely pathogenic 0.528451 1 Thr 15944 T A Neutral 0.299089 1 Thr 15944 T C Neutral 0.215342 1 Thr 15944 T G Neutral 0.299089 1 Thr 15945 C A Pathogenic 0.71995 1 Thr 15945 C G Pathogenic 0.71995 1 Thr 15945 C T Pathogenic 0.71995 1 Thr 15946 C A Likely pathogenic 0.529361 1 Thr 15946 C G Likely pathogenic 0.529361 1 Thr 15946 C T Likely neutral 0.438712 1 Thr 15947 A C Neutral 0.173185 0 Thr 15947 A G Neutral 0.279403 0 Thr 15947 A T Neutral 0.182028 0 Thr 15948 A C Neutral 0.25759 1 Thr 15948 A G Neutral 0.222027 0 Thr 15948 A T Neutral 0.25759 0 Thr 15949 G A Likely neutral 0.324313 1 Thr 15949 G C Likely neutral 0.393341 1 Thr 15949 G T Likely neutral 0.393341 1 Thr 15950 G A Neutral 0.231938 1 Thr 15950 G C Likely neutral 0.438175 1 Thr 15950 G T Likely neutral 0.438175 1 Thr 15951 A C Neutral 0.269853 1 Thr 15951 A G Neutral 0.099395 0 Thr 15951 A T Neutral 0.269853 1 Thr 15952 C A Pathogenic 0.75682 1 Thr 15952 C G Pathogenic 0.75682 1 Thr 15952 C T Pathogenic 0.702962 1 Thr 15953 A C Likely neutral 0.411876 1 Thr 15953 A G Likely neutral 0.471841 1 Thr 15953 A T Likely neutral 0.471841 1 Trp 5512 A C Likely pathogenic 0.597953 1 Trp 5512 A G Likely pathogenic 0.597953 1 Trp 5512 A T Likely pathogenic 0.597953 1 Trp 5513 G A Pathogenic 0.922413 1 Trp 5513 G C Pathogenic 0.922413 1 Trp 5513 G T Pathogenic 0.922413 1 Trp 5514 A C Likely neutral 0.406457 1 Trp 5514 A G Likely neutral 0.367531 1 Trp 5514 A T Likely neutral 0.406457 1 Trp 5515 A C Likely pathogenic 0.597211 1 Trp 5515 A G Likely neutral 0.470197 1 Trp 5515 A T Likely pathogenic 0.597211 1 Trp 5516 A C Likely neutral 0.378625 1 Trp 5516 A G Neutral 0.254524 1 Trp 5516 A T Likely neutral 0.378625 1 Trp 5517 T A Likely neutral 0.453193 1 Trp 5517 T C Likely neutral 0.453193 1 Trp 5517 T G Likely neutral 0.493033 1 Trp 5518 T A Pathogenic 0.79398 1 Trp 5518 T C Pathogenic 0.79398 1 Trp 5518 T G Pathogenic 0.79398 1 Trp 5519 T A Pathogenic 0.687236 1 Trp 5519 T C Pathogenic 0.687236 1 Trp 5519 T G Pathogenic 0.687236 1 Trp 5520 A C Likely pathogenic 0.551845 1 Trp 5520 A G Likely pathogenic 0.551845 1 Trp 5520 A T Likely pathogenic 0.551845 1 Trp 5521 G A Pathogenic 0.741292 1 Trp 5521 G C Pathogenic 0.741292 1 Trp 5521 G T Pathogenic 0.741292 1 Trp 5522 G A Pathogenic 0.922515 1 Trp 5522 G C Pathogenic 0.922515 1 Trp 5522 G T Pathogenic 0.922515 1 Trp 5523 T A Neutral 0.186119 1 Trp 5523 T C Neutral 0.169426 0 Trp 5523 T G Neutral 0.209366 1 Trp 5524 T A Pathogenic 0.688287 1 Trp 5524 T C Pathogenic 0.688287 1 Trp 5524 T G Pathogenic 0.688287 1 Trp 5525 A C Pathogenic 0.773953 1 Trp 5525 A G Pathogenic 0.773953 1 Trp 5525 A T Pathogenic 0.773953 1 Trp 5526 A C Neutral 0.196869 0 Trp 5526 A G Neutral 0.218266 0 Trp 5526 A T Neutral 0.164174 0 Trp 5527 A C Neutral 0.161273 0 Trp 5527 A G Neutral 0.137588 0 Trp 5527 A T Neutral 0.161273 0 Trp 5528 T A Neutral 0.124652 0 Trp 5528 T C Neutral 0.136198 0 Trp 5528 T G Neutral 0.226665 0 Trp 5529 A C Neutral 0.097234 0 Trp 5529 A G Neutral 0.23399 0 Trp 5529 A T Neutral 0.089557 0 Trp 5530 C A Neutral 0.297049 0 Trp 5530 C G Neutral 0.297049 0 Trp 5530 C T Neutral 0.226736 0 Trp 5531 A C Likely pathogenic 0.614457 0 Trp 5531 A G Likely pathogenic 0.614457 0 Trp 5531 A T Likely pathogenic 0.614457 0 Trp 5532 G A Pathogenic 0.842272 1 Trp 5532 G C Pathogenic 0.842272 1 Trp 5532 G T Pathogenic 0.842272 1 Trp 5533 A C Likely pathogenic 0.537935 1 Trp 5533 A G Likely pathogenic 0.537935 0 Trp 5533 A T Likely neutral 0.415347 1 Trp 5534 C A Pathogenic 0.660627 1 Trp 5534 C G Pathogenic 0.660627 1 Trp 5534 C T Likely pathogenic 0.629609 1 Trp 5535 C A Pathogenic 0.818507 1 Trp 5535 C G Pathogenic 0.818507 1 Trp 5535 C T Pathogenic 0.818507 1 Trp 5536 A C Neutral 0.292853 0 Trp 5536 A G Neutral 0.226716 0 Trp 5536 A T Neutral 0.242777 0 Trp 5537 A C Neutral 0.260629 1 Trp 5537 A G Neutral 0.28435 1 Trp 5537 A T Neutral 0.349229 1 Trp 5538 G A Pathogenic 0.72402 1 Trp 5538 G C Pathogenic 0.766744 1 Trp 5538 G T Pathogenic 0.745791 1 Trp 5539 A C Neutral 0.333896 0 Trp 5539 A G Neutral 0.212846 0 Trp 5539 A T Neutral 0.333896 0 Trp 5540 G A Pathogenic 0.916975 1 Trp 5540 G C Pathogenic 0.916975 1 Trp 5540 G T Pathogenic 0.916975 1 Trp 5541 C A Likely pathogenic 0.640928 1 Trp 5541 C G Likely pathogenic 0.640928 1 Trp 5541 C T Likely pathogenic 0.640928 1 Trp 5542 C A Likely pathogenic 0.609069 1 Trp 5542 C G Likely pathogenic 0.609069 1 Trp 5542 C T Likely pathogenic 0.609069 1 Trp 5543 T A Likely neutral 0.3832 1 Trp 5543 T C Likely neutral 0.3832 1 Trp 5543 T G Likely neutral 0.3832 1 Trp 5544 T A Likely neutral 0.414136 1 Trp 5544 T C Likely neutral 0.414136 1 Trp 5544 T G Likely neutral 0.414136 1 Trp 5545 C A Pathogenic 0.842728 1 Trp 5545 C G Pathogenic 0.842728 1 Trp 5545 C T Pathogenic 0.842728 1 Trp 5546 A C Likely pathogenic 0.643438 1 Trp 5546 A G Likely pathogenic 0.643438 1 Trp 5546 A T Likely pathogenic 0.643438 1 Trp 5547 A C Pathogenic 0.69395 1 Trp 5547 A G Pathogenic 0.69395 1 Trp 5547 A T Pathogenic 0.69395 1 Trp 5548 A C Likely neutral 0.387825 1 Trp 5548 A G Likely neutral 0.387825 1 Trp 5548 A T Likely neutral 0.387825 1 Trp 5549 G A Pathogenic 0.916975 1 Trp 5549 G C Pathogenic 0.916975 1 Trp 5549 G T Pathogenic 0.916975 1 Trp 5550 C A Likely pathogenic 0.640928 1 Trp 5550 C G Likely pathogenic 0.640928 1 Trp 5550 C T Likely pathogenic 0.640928 1 Trp 5551 C A Neutral 0.214552 0 Trp 5551 C G Neutral 0.214552 0 Trp 5551 C T Neutral 0.152615 0 Trp 5552 C A Likely pathogenic 0.628756 1 Trp 5552 C G Likely pathogenic 0.628756 1 Trp 5552 C T Likely neutral 0.4994 1 Trp 5553 T A Likely pathogenic 0.574301 1 Trp 5553 T C Likely neutral 0.45425 1 Trp 5553 T G Likely pathogenic 0.574301 1 Trp 5554 C A Neutral 0.204051 0 Trp 5554 C G Neutral 0.293624 0 Trp 5554 C T Neutral 0.187176 0 Trp 5555 A C Pathogenic 0.693833 1 Trp 5555 A G Pathogenic 0.693833 1 Trp 5555 A T Pathogenic 0.693833 1 Trp 5556 G A Pathogenic 0.857369 1 Trp 5556 G C Pathogenic 0.857369 1 Trp 5556 G T Pathogenic 0.857369 1 Trp 5557 T A Neutral 0.121745 0 Trp 5557 T C Neutral 0.120991 0 Trp 5557 T G Neutral 0.22355 0 Trp 5558 A C Pathogenic 0.855084 1 Trp 5558 A G Pathogenic 0.855084 1 Trp 5558 A T Pathogenic 0.855084 1 Trp 5559 A C Likely neutral 0.398614 1 Trp 5559 A G Likely neutral 0.398614 1 Trp 5559 A T Likely neutral 0.398614 1 Trp 5560 G A Pathogenic 0.722128 1 Trp 5560 G C Pathogenic 0.736561 1 Trp 5560 G T Pathogenic 0.736561 1 Trp 5561 T A Likely neutral 0.340067 1 Trp 5561 T C Likely neutral 0.364834 1 Trp 5561 T G Likely neutral 0.340067 1 Trp 5562 T A Neutral 0.141766 0 Trp 5562 T C Neutral 0.127936 0 Trp 5562 T G Neutral 0.153419 0 Trp 5563 G A Neutral 0.118986 0 Trp 5563 G C Neutral 0.103012 0 Trp 5563 G T Neutral 0.112039 0 Trp 5564 C A Neutral 0.106499 0 Trp 5564 C G Neutral 0.248927 0 Trp 5564 C T Neutral 0.106322 0 Trp 5565 A C Neutral 0.068889 0 Trp 5565 A G Neutral 0.204346 0 Trp 5565 A T Neutral 0.072555 0 Trp 5566 A C Neutral 0.132466 0 Trp 5566 A G Neutral 0.13757 0 Trp 5566 A T Neutral 0.13757 0 Trp 5567 T A Neutral 0.219474 0 Trp 5567 T C Neutral 0.178248 0 Trp 5567 T G Neutral 0.263867 0 Trp 5568 A C Neutral 0.24467 1 Trp 5568 A G Neutral 0.122773 1 Trp 5568 A T Neutral 0.24467 1 Trp 5569 C A Likely pathogenic 0.591346 1 Trp 5569 C G Likely pathogenic 0.591346 1 Trp 5569 C T Likely pathogenic 0.591189 1 Trp 5570 T A Likely pathogenic 0.557289 1 Trp 5570 T C Likely pathogenic 0.557289 1 Trp 5570 T G Likely pathogenic 0.557289 1 Trp 5571 T A Pathogenic 0.829214 1 Trp 5571 T C Pathogenic 0.829214 1 Trp 5571 T G Pathogenic 0.829214 1 Trp 5572 A C Pathogenic 0.855084 1 Trp 5572 A G Pathogenic 0.855084 1 Trp 5572 A T Pathogenic 0.855084 1 Trp 5573 A C Pathogenic 0.638009 1 Trp 5573 A G Likely pathogenic 0.571772 1 Trp 5573 A T Likely pathogenic 0.571772 1 Trp 5574 T A Neutral 0.321573 1 Trp 5574 T C Neutral 0.273117 1 Trp 5574 T G Neutral 0.321573 1 Trp 5575 T A Likely pathogenic 0.535449 1 Trp 5575 T C Likely neutral 0.403817 1 Trp 5575 T G Likely pathogenic 0.535449 1 Trp 5576 T A Likely neutral 0.418812 1 Trp 5576 T C Neutral 0.332292 1 Trp 5576 T G Likely neutral 0.418812 1 Trp 5577 C A Pathogenic 0.87982 1 Trp 5577 C G Pathogenic 0.87982 1 Trp 5577 C T Pathogenic 0.87982 1 Trp 5578 T A Likely pathogenic 0.676586 1 Trp 5578 T C Likely pathogenic 0.676586 1 Trp 5578 T G Likely pathogenic 0.676586 1 Trp 5579 G A Pathogenic 0.74339 1 Trp 5579 G C Pathogenic 0.74339 1 Trp 5579 G T Pathogenic 0.74339 1 Tyr 5891 G A Likely pathogenic 0.566028 1 Tyr 5891 G C Likely pathogenic 0.566028 1 Tyr 5891 G T Likely pathogenic 0.566028 1 Tyr 5890 G A Pathogenic 0.699232 1 Tyr 5890 G C Pathogenic 0.807849 1 Tyr 5890 G T Pathogenic 0.807849 1 Tyr 5889 T A Likely pathogenic 0.567584 1 Tyr 5889 T C Likely pathogenic 0.552298 0 Tyr 5889 T G Likely pathogenic 0.567584 1 Tyr 5888 A C Pathogenic 0.675364 1 Tyr 5888 A G Likely pathogenic 0.652202 1 Tyr 5888 A T Pathogenic 0.675364 1 Tyr 5887 A C Likely pathogenic 0.544754 1 Tyr 5887 A G Likely neutral 0.41559 1 Tyr 5887 A T Likely pathogenic 0.544754 1 Tyr 5886 A C Likely pathogenic 0.543772 1 Tyr 5886 A G Likely neutral 0.462275 1 Tyr 5886 A T Likely pathogenic 0.543772 1 Tyr 5885 A C Pathogenic 0.639455 1 Tyr 5885 A G Likely pathogenic 0.529556 1 Tyr 5885 A T Pathogenic 0.639455 1 Tyr 5884 T A Neutral 0.274396 1 Tyr 5884 T C Neutral 0.274396 1 Tyr 5884 T G Neutral 0.274396 1 Tyr 5883 G A Likely pathogenic 0.599765 1 Tyr 5883 G C Likely pathogenic 0.599765 1 Tyr 5883 G T Likely pathogenic 0.599765 1 Tyr 5882 G A Pathogenic 0.652536 0 Tyr 5882 G C Pathogenic 0.652536 1 Tyr 5882 G T Pathogenic 0.652536 1 Tyr 5881 C A Pathogenic 0.77927 1 Tyr 5881 C G Pathogenic 0.77927 1 Tyr 5881 C T Pathogenic 0.77927 1 Tyr 5880 T A Likely neutral 0.48008 1 Tyr 5880 T C Likely neutral 0.408953 0 Tyr 5880 T G Likely neutral 0.48008 1 Tyr 5879 G A Pathogenic 0.759021 1 Tyr 5879 G C Pathogenic 0.759021 1 Tyr 5879 G T Pathogenic 0.759021 1 Tyr 5878 A C Likely pathogenic 0.615024 1 Tyr 5878 A G Likely pathogenic 0.615024 1 Tyr 5878 A T Likely pathogenic 0.615024 1 Tyr 5877 G A Pathogenic 0.733829 0 Tyr 5877 G C Pathogenic 0.756255 0 Tyr 5877 G T Pathogenic 0.756255 0 Tyr 5876 T A Neutral 0.300563 1 Tyr 5876 T C Neutral 0.300563 1 Tyr 5876 T G Likely neutral 0.326931 1 Tyr 5875 G A Neutral 0.188192 0 Tyr 5875 G C Neutral 0.325222 0 Tyr 5875 G T Neutral 0.202622 0 Tyr 5874 A C Likely neutral 0.430041 1 Tyr 5874 A G Likely neutral 0.410451 1 Tyr 5874 A T Likely neutral 0.430041 0 Tyr 5873 A C Neutral 0.283986 1 Tyr 5873 A G Neutral 0.190742 0 Tyr 5873 A T Neutral 0.283986 1 Tyr 5872 G A Pathogenic 0.878552 1 Tyr 5872 G C Pathogenic 0.878552 1 Tyr 5872 G T Pathogenic 0.878552 1 Tyr 5871 C A Pathogenic 0.677962 1 Tyr 5871 C G Pathogenic 0.677962 1 Tyr 5871 C T Likely pathogenic 0.593063 0 Tyr 5870 A C Likely neutral 0.436136 1 Tyr 5870 A G Likely neutral 0.413631 1 Tyr 5870 A T Likely neutral 0.436136 1 Tyr 5869 T A Pathogenic 0.638231 1 Tyr 5869 T C Pathogenic 0.638231 1 Tyr 5869 T G Pathogenic 0.638231 1 Tyr 5868 T A Likely neutral 0.456958 1 Tyr 5868 T C Likely neutral 0.456958 1 Tyr 5868 T G Likely neutral 0.456958 1 Tyr 5867 G A Likely neutral 0.444132 0 Tyr 5867 G C Likely neutral 0.425295 0 Tyr 5867 G T Likely neutral 0.425295 0 Tyr 5866 G A Pathogenic 0.755929 1 Tyr 5866 G C Pathogenic 0.755929 1 Tyr 5866 G T Pathogenic 0.755929 1 Tyr 5865 A C Neutral 0.346132 1 Tyr 5865 A G Neutral 0.191444 0 Tyr 5865 A T Neutral 0.346132 1 Tyr 5864 C A Likely pathogenic 0.560761 1 Tyr 5864 C G Likely pathogenic 0.560761 1 Tyr 5864 C T Likely pathogenic 0.560761 1 Tyr 5863 T A Likely neutral 0.469432 1 Tyr 5863 T C Likely neutral 0.469432 1 Tyr 5863 T G Likely neutral 0.469432 1 Tyr 5862 G A Pathogenic 0.71321 1 Tyr 5862 G C Pathogenic 0.71321 1 Tyr 5862 G T Pathogenic 0.71321 1 Tyr 5861 T A Likely neutral 0.392006 1 Tyr 5861 T C Likely neutral 0.392006 1 Tyr 5861 T G Likely neutral 0.392006 1 Tyr 5860 A C Likely pathogenic 0.613322 1 Tyr 5860 A G Likely pathogenic 0.613322 1 Tyr 5860 A T Likely pathogenic 0.613322 1 Tyr 5859 A C Likely pathogenic 0.612803 1 Tyr 5859 A G Likely pathogenic 0.612803 1 Tyr 5859 A T Likely pathogenic 0.612803 1 Tyr 5858 A C Likely pathogenic 0.635665 1 Tyr 5858 A G Likely pathogenic 0.635665 1 Tyr 5858 A T Likely pathogenic 0.635665 1 Tyr 5857 T A Likely neutral 0.419483 1 Tyr 5857 T C Neutral 0.332919 0 Tyr 5857 T G Likely neutral 0.419483 1 Tyr 5856 C A Pathogenic 0.872772 1 Tyr 5856 C G Pathogenic 0.872772 1 Tyr 5856 C T Pathogenic 0.872772 1 Tyr 5855 T A Likely pathogenic 0.602417 0 Tyr 5855 T C Likely pathogenic 0.584404 0 Tyr 5855 T G Likely pathogenic 0.602417 0 Tyr 5854 A C Pathogenic 0.777675 1 Tyr 5854 A G Pathogenic 0.777675 1 Tyr 5854 A T Pathogenic 0.777675 1 Tyr 5853 A C Pathogenic 0.771652 1 Tyr 5853 A G Pathogenic 0.771652 1 Tyr 5853 A T Pathogenic 0.771652 1 Tyr 5852 A C Neutral 0.189589 0 Tyr 5852 A G Neutral 0.156911 0 Tyr 5852 A T Neutral 0.189589 0 Tyr 5851 G A Likely neutral 0.343963 0 Tyr 5851 G C Likely neutral 0.343199 0 Tyr 5851 G T Likely neutral 0.343199 0 Tyr 5850 A C Pathogenic 0.656308 1 Tyr 5850 A G Pathogenic 0.656308 1 Tyr 5850 A T Pathogenic 0.656308 1 Tyr 5849 C A Likely pathogenic 0.523403 0 Tyr 5849 C G Likely pathogenic 0.523403 0 Tyr 5849 C T Likely neutral 0.429598 0 Tyr 5848 A C Likely neutral 0.484956 1 Tyr 5848 A G Neutral 0.355051 1 Tyr 5848 A T Likely neutral 0.484956 1 Tyr 5847 G A Likely pathogenic 0.566028 1 Tyr 5847 G C Likely pathogenic 0.566028 1 Tyr 5847 G T Likely pathogenic 0.566028 1 Tyr 5846 G A Neutral 0.192933 0 Tyr 5846 G C Neutral 0.246317 0 Tyr 5846 G T Neutral 0.246317 0 Tyr 5845 G A Likely neutral 0.485138 1 Tyr 5845 G C Likely pathogenic 0.550972 1 Tyr 5845 G T Likely pathogenic 0.550972 1 Tyr 5844 G A Pathogenic 0.699232 1 Tyr 5844 G C Pathogenic 0.807849 1 Tyr 5844 G T Pathogenic 0.807849 1 Tyr 5843 T A Neutral 0.067953 0 Tyr 5843 T C Neutral 0.081426 0 Tyr 5843 T G Neutral 0.123361 0 Tyr 5842 T A Neutral 0.20499 0 Tyr 5842 T C Neutral 0.20499 0 Tyr 5842 T G Neutral 0.172327 0 Tyr 5841 A C Neutral 0.126839 0 Tyr 5841 A G Neutral 0.12175 0 Tyr 5841 A T Neutral 0.137389 0 Tyr 5840 G A Neutral 0.124559 0 Tyr 5840 G C Neutral 0.12441 0 Tyr 5840 G T Neutral 0.200063 0 Tyr 5839 G A Neutral 0.15067 0 Tyr 5839 G C Neutral 0.138591 0 Tyr 5839 G T Neutral 0.138584 0 Tyr 5838 C A Likely neutral 0.480853 1 Tyr 5838 C G Likely pathogenic 0.522092 1 Tyr 5838 C T Likely pathogenic 0.522092 1 Tyr 5837 C A Pathogenic 0.736003 1 Tyr 5837 C G Pathogenic 0.736003 1 Tyr 5837 C T Pathogenic 0.703567 1 Tyr 5836 T A Neutral 0.380113 0 Tyr 5836 T C Neutral 0.308453 0 Tyr 5836 T G Neutral 0.380113 0 Tyr 5835 C A Pathogenic 0.816508 1 Tyr 5835 C G Pathogenic 0.816508 1 Tyr 5835 C T Pathogenic 0.775613 1 Tyr 5834 T A Likely neutral 0.467816 1 Tyr 5834 T C Likely neutral 0.422755 1 Tyr 5834 T G Likely neutral 0.467816 1 Tyr 5833 T A Pathogenic 0.71886 1 Tyr 5833 T C Pathogenic 0.698648 1 Tyr 5833 T G Pathogenic 0.71886 1 Tyr 5832 T A Likely pathogenic 0.510841 1 Tyr 5832 T C Likely neutral 0.378166 1 Tyr 5832 T G Likely pathogenic 0.510841 1 Tyr 5831 T A Pathogenic 0.681074 1 Tyr 5831 T C Likely pathogenic 0.616584 1 Tyr 5831 T G Pathogenic 0.681074 1 Tyr 5830 T A Pathogenic 0.709134 1 Tyr 5830 T C Pathogenic 0.683155 1 Tyr 5830 T G Pathogenic 0.709134 1 Tyr 5829 A C Likely neutral 0.434744 1 Tyr 5829 A G Neutral 0.353317 0 Tyr 5829 A T Likely neutral 0.434744 1 Tyr 5828 C A Likely neutral 0.416491 1 Tyr 5828 C G Likely neutral 0.416491 1 Tyr 5828 C T Neutral 0.301549 1 Tyr 5827 C A Pathogenic 0.80198 1 Tyr 5827 C G Pathogenic 0.80198 1 Tyr 5827 C T Pathogenic 0.80198 1 Val 1602 C A Pathogenic 0.818507 1 Val 1602 C G Pathogenic 0.818507 1 Val 1602 C T Pathogenic 0.818507 1 Val 1603 A C Pathogenic 0.745681 1 Val 1603 A G Pathogenic 0.745681 1 Val 1603 A T Pathogenic 0.745681 1 Val 1604 G A Likely neutral 0.451534 1 Val 1604 G C Likely neutral 0.474076 1 Val 1604 G T Likely neutral 0.450714 1 Val 1605 A C Neutral 0.259081 1 Val 1605 A G Neutral 0.223913 1 Val 1605 A T Neutral 0.315932 1 Val 1606 G A Pathogenic 0.779739 1 Val 1606 G C Pathogenic 0.790112 1 Val 1606 G T Pathogenic 0.790112 1 Val 1607 T A Neutral 0.165038 0 Val 1607 T C Neutral 0.102979 0 Val 1607 T G Neutral 0.165038 0 Val 1608 G A Likely pathogenic 0.580013 1 Val 1608 G C Pathogenic 0.652515 1 Val 1608 G T Pathogenic 0.652515 1 Val 1609 T A Likely pathogenic 0.552764 1 Val 1609 T C Likely pathogenic 0.552764 1 Val 1609 T G Likely pathogenic 0.552764 1 Val 1610 A C Likely pathogenic 0.551845 1 Val 1610 A G Likely pathogenic 0.551845 1 Val 1610 A T Likely pathogenic 0.551845 1 Val 1611 G A Pathogenic 0.918634 1 Val 1611 G C Pathogenic 0.918634 1 Val 1611 G T Pathogenic 0.918634 1 Val 1612 C A Pathogenic 0.825152 1 Val 1612 C G Pathogenic 0.825152 1 Val 1612 C T Pathogenic 0.825152 1 Val 1613 T A Likely pathogenic 0.557289 1 Val 1613 T C Likely pathogenic 0.557289 1 Val 1613 T G Likely pathogenic 0.557289 1 Val 1614 T A Pathogenic 0.683773 1 Val 1614 T C Likely pathogenic 0.613899 1 Val 1614 T G Pathogenic 0.683773 1 Val 1615 A C Pathogenic 0.773953 0 Val 1615 A G Pathogenic 0.773953 0 Val 1615 A T Pathogenic 0.773953 0 Val 1616 A C Likely pathogenic 0.653947 0 Val 1616 A G Likely pathogenic 0.653947 0 Val 1616 A T Likely pathogenic 0.58548 0 Val 1617 C A Neutral 0.184392 0 Val 1617 C G Neutral 0.224777 0 Val 1617 C T Neutral 0.184618 0 Val 1618 A C Neutral 0.092506 0 Val 1618 A G Neutral 0.245585 0 Val 1618 A T Neutral 0.092506 0 Val 1619 C A Neutral 0.168419 0 Val 1619 C G Neutral 0.302624 0 Val 1619 C T Neutral 0.169324 0 Val 1620 A C Likely pathogenic 0.643438 1 Val 1620 A G Likely pathogenic 0.643438 1 Val 1620 A T Likely pathogenic 0.643438 1 Val 1621 A C Pathogenic 0.814917 1 Val 1621 A G Pathogenic 0.814917 1 Val 1621 A T Pathogenic 0.814917 1 Val 1622 A C Likely pathogenic 0.552649 1 Val 1622 A G Likely pathogenic 0.552649 1 Val 1622 A T Likely pathogenic 0.552649 1 Val 1623 G A Pathogenic 0.916975 1 Val 1623 G C Pathogenic 0.916975 1 Val 1623 G T Pathogenic 0.916975 1 Val 1624 C A Pathogenic 0.81625 1 Val 1624 C G Pathogenic 0.81625 1 Val 1624 C T Pathogenic 0.81625 1 Val 1625 A C Likely neutral 0.4663 1 Val 1625 A G Likely neutral 0.4663 1 Val 1625 A T Likely neutral 0.432579 1 Val 1626 C A Neutral 0.222835 1 Val 1626 C G Neutral 0.273098 1 Val 1626 C T Neutral 0.233046 0 Val 1627 C A Likely pathogenic 0.536431 1 Val 1627 C G Likely pathogenic 0.536431 1 Val 1627 C T Likely neutral 0.462081 1 Val 1628 C A Neutral 0.269017 0 Val 1628 C G Neutral 0.269017 0 Val 1628 C T Neutral 0.210215 0 Val 1629 A C Likely neutral 0.460113 1 Val 1629 A G Likely pathogenic 0.517984 0 Val 1629 A T Likely neutral 0.422284 1 Val 1630 A C Likely pathogenic 0.506865 1 Val 1630 A G Likely pathogenic 0.554686 1 Val 1630 A T Likely pathogenic 0.506865 1 Val 1631 C A Likely pathogenic 0.620733 1 Val 1631 C G Likely pathogenic 0.620733 1 Val 1631 C T Likely pathogenic 0.620733 1 Val 1632 T A Neutral 0.229313 0 Val 1632 T C Neutral 0.196229 0 Val 1632 T G Neutral 0.229313 0 Val 1633 T A Likely pathogenic 0.658185 1 Val 1633 T C Likely pathogenic 0.658185 1 Val 1633 T G Likely pathogenic 0.658185 1 Val 1634 A C Likely neutral 0.492288 1 Val 1634 A G Likely neutral 0.492288 1 Val 1634 A T Likely neutral 0.492288 1 Val 1635 C A Pathogenic 0.694013 1 Val 1635 C G Pathogenic 0.694013 1 Val 1635 C T Pathogenic 0.694013 1 Val 1636 A C Likely pathogenic 0.573432 1 Val 1636 A G Likely pathogenic 0.573432 1 Val 1636 A T Likely pathogenic 0.573432 1 Val 1637 C A Likely pathogenic 0.620733 1 Val 1637 C G Likely pathogenic 0.620733 1 Val 1637 C T Likely pathogenic 0.620733 1 Val 1638 T A Likely neutral 0.482162 1 Val 1638 T C Likely pathogenic 0.59443 1 Val 1638 T G Likely neutral 0.482162 1 Val 1639 T A Likely neutral 0.482599 1 Val 1639 T C Likely pathogenic 0.51963 0 Val 1639 T G Likely neutral 0.482599 1 Val 1640 A C Neutral 0.151947 0 Val 1640 A G Neutral 0.12219 0 Val 1640 A T Neutral 0.206442 0 Val 1641 G A Likely neutral 0.379025 1 Val 1641 G C Likely neutral 0.443954 1 Val 1641 G T Likely neutral 0.443954 1 Val 1642 G A Likely neutral 0.356067 0 Val 1642 G C Likely neutral 0.370489 1 Val 1642 G T Likely neutral 0.370489 1 Val 1643 A C Likely pathogenic 0.615723 1 Val 1643 A G Likely pathogenic 0.615723 1 Val 1643 A T Likely pathogenic 0.615723 1 Val 1644 G A Pathogenic 0.67475 1 Val 1644 G C Pathogenic 0.714829 1 Val 1644 G T Pathogenic 0.714829 1 Val 1645 A C Pathogenic 0.684314 1 Val 1645 A G Pathogenic 0.684314 1 Val 1645 A T Pathogenic 0.684314 1 Val 1646 T A Likely neutral 0.419863 1 Val 1646 T C Likely neutral 0.419863 1 Val 1646 T G Likely neutral 0.436615 1 Val 1647 T A Neutral 0.173794 0 Val 1647 T C Neutral 0.165093 0 Val 1647 T G Neutral 0.264192 0 Val 1648 T A Likely pathogenic 0.506978 1 Val 1648 T C Likely neutral 0.455924 0 Val 1648 T G Likely pathogenic 0.506978 1 Val 1649 C A Pathogenic 0.800913 1 Val 1649 C G Pathogenic 0.800913 1 Val 1649 C T Pathogenic 0.762121 1 Val 1650 A C Likely pathogenic 0.555265 1 Val 1650 A G Likely pathogenic 0.555265 1 Val 1650 A T Likely pathogenic 0.604743 1 Val 1651 A C Neutral 0.237235 0 Val 1651 A G Neutral 0.26665 0 Val 1651 A T Neutral 0.230133 0 Val 1652 C A Neutral 0.196636 0 Val 1652 C G Neutral 0.228122 0 Val 1652 C T Neutral 0.207634 0 Val 1653 T A Neutral 0.145633 0 Val 1653 T C Neutral 0.142241 0 Val 1653 T G Neutral 0.133693 0 Val 1654 T A Neutral 0.12057 0 Val 1654 T C Neutral 0.118854 0 Val 1654 T G Neutral 0.255485 0 Val 1655 A C Neutral 0.089963 0 Val 1655 A G Neutral 0.168334 0 Val 1655 A T Neutral 0.139142 0 Val 1656 A C Neutral 0.182689 0 Val 1656 A G Likely neutral 0.276865 0 Val 1656 A T Neutral 0.23258 0 Val 1657 C A Neutral 0.220846 0 Val 1657 C G Neutral 0.292524 0 Val 1657 C T Neutral 0.205122 0 Val 1658 T A Neutral 0.252129 0 Val 1658 T C Neutral 0.247647 0 Val 1658 T G Neutral 0.245721 0 Val 1659 T A Likely neutral 0.358341 1 Val 1659 T C Neutral 0.219053 1 Val 1659 T G Likely neutral 0.321079 1 Val 1660 G A Pathogenic 0.857104 1 Val 1660 G C Pathogenic 0.901169 1 Val 1660 G T Pathogenic 0.901169 1 Val 1661 A C Likely pathogenic 0.51685 1 Val 1661 A G Likely neutral 0.368605 0 Val 1661 A T Likely pathogenic 0.51685 1 Val 1662 C A Neutral 0.111774 0 Val 1662 C G Neutral 0.195341 0 Val 1662 C T Neutral 0.110309 0 Val 1663 C A Neutral 0.347093 1 Val 1663 C G Neutral 0.310174 1 Val 1663 C T Neutral 0.26243 1 Val 1664 G A Neutral 0.167118 0 Val 1664 G C Neutral 0.165542 0 Val 1664 G T Neutral 0.237694 0 Val 1665 C A Likely pathogenic 0.510362 1 Val 1665 C G Likely pathogenic 0.510362 1 Val 1665 C T Likely neutral 0.401464 1 Val 1666 T A Likely pathogenic 0.515111 1 Val 1666 T C Likely neutral 0.458156 1 Val 1666 T G Likely pathogenic 0.515111 1 Val 1667 C A Likely neutral 0.427855 1 Val 1667 C G Likely neutral 0.461296 1 Val 1667 C T Likely neutral 0.431584 1 Val 1668 T A Likely pathogenic 0.676586 1 Val 1668 T C Likely pathogenic 0.676586 1 Val 1668 T G Likely pathogenic 0.676586 1 Val 1669 G A Pathogenic 0.93127 1 Val 1669 G C Pathogenic 0.93127 1 Val 1669 G T Pathogenic 0.93127 1 Val 1670 A C Likely pathogenic 0.627038 1 Val 1670 A G Likely pathogenic 0.627038 1 Val 1670 A T Likely pathogenic 0.627038 1