Factor D deficiency

Factor D is part of the alternative complement pathway and is identical to adipisin. It is synthesized in adypocytes, muscle cells, lung, and monocytes/macrophages. Factor D converts factor B to its end product.

Alternative names

Complement factor D deficiency

Classification

  • Defects of the alternative complement pathway

Inheritance

Autosomal recessive

OMIM

*134350 Factor D

Cross references

Phenotypically related immunodeficiencies

IDR factfile for C4 binding protein α deficiency

Incidence

Incidence is not known.