Properdin factor C deficiency

Gene Information

Names

HUGO name: CFP

Alias(es):

  • BFD
  • PFC
  • PFD
  • properdin P factor, complement
  • Properdin precursor
  • Factor P

Localization

Reference sequences

Chromosomal location

Maps

Protein Information

Description

Protein function:

A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3-and C5-convertase enzyme complexes.

Expression

Expression pattern for human

Tissue Expression (%) Clones
adipose, white adipose tissue 27.20 1:987
whole blood 21.96 2:2445
spleen 11.14 3:7229
mixed 6.67 15:60341
ovary (pool of 3) 6.13 1:4380
leukocyte 5.98 2:8982
aorta 5.23 2:10275
pituitary 4.53 1:5926
muscle, pectoral muscle 3.59 2:14965
B-cells 3.25 2:16533