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The most common finding in patients with factor H deficiency is renal disease. Glomerulonephritis, IgA nephropathy, and hemolytic uremic syndrome have been described in some patients. Infections with neisserial species and encapsulated organisms are also common. Some patients with factor H deficiency are asymptomatic.
Diagnosis
Diagnostic recommendations
Additional Information
Therapeutic options
- Fresh frozen plasma is used for emergent replacement of complements components. Supportive therapy is used for complement deficiencies. Prophylactic antibiotics for the infections.
- Complement deficiency, eMedicine
- Complement deficiency, eMedicine