Printable factfile
Familial Mediterranean fever is divided into types 1 and 2. Patients with FMF type 1 have short episodes of inflammation and serositis including fever, peritonitis, synovitis, pleuritis, and rarely, pericarditis and meningitis. Amyloidoisis is the most severe complication, can lead to renal failure. Patients with FMF type 2 have amyloidosis, as the first clinical manifestation of disease in an asymptomatic individual.
Diagnosis
Diagnostic recommendations
Additional Information
- Mediterranean fever, familial, ORPHANET
- La Febbre Mediterranea Familiare, Centro Febbri Periodiche
- MetaFMF website
- Mediterranean fever, familial, eMedicine
- Familial Mediterranean fever, The Doctor's Doctor
- Mediterranean Fever, Familial, National Organization for Rare Disorders (NORD)
- Familial Mediterranean fever, National Center for Biotechnology Information
- INFEVERS (Internet periodic FEVERS resource)
- Familial Mediterranean Fever (FMF) Disease, Tel Aviv University
- Familial Mediterranean Fever, GeneTest
Diagnostic laboratories
Clinical:
Genetic:
Therapeutic options
- Effective treatment with colchicine. Interferon-alpha for patients with colchicine-resistant disease.
- Mediterranean fever, familial, eMedicine