Printable factfile
Gene Information
Names
HUGO name: BIRC4
Localization
Reference sequences
- DNA: D0120 (IDRefSeq)
- cDNA: U45880 (EMBL)
- Protein: P98170 (SWISSPROT)
- Other Sequences
Chromosomal location
Maps
Other gene-based resources
Protein Information
Description
Protein function:
Apoptotic suppressor. Inhibitor of caspase-3, -7 and -9
Subunit:
Interacts with smac and with prss25; these interactions inhibit apoptotic suppressor activity
Subcellular location:
Cytoplasm
Tissue specificity:
Ubiquitous, except peripheral blood leukocytes
Similarity:
Belongs to the iap family
Domains
Other features
Baculoviral iap repeat-containing protein 4: 1-497
Zinc finger region Ring-type: 450-485
Other related resourses:
Expression
Expression pattern for human
| Tissue | Expression (%) | Clones |
|---|---|---|
| pharynx | 13.74 | 1:4158 |
| esophagus | 5.89 | 2:19405 |
| cochlea | 4.58 | 1:12466 |
| lymph_node | 4.33 | 6:79183 |
| kidney | 4.15 | 14:192682 |
| stomach | 3.91 | 5:73010 |
| nerve | 3.65 | 1:15651 |
| vascular | 3.60 | 3:47560 |
| colon | 3.47 | 6:98776 |
| lung | 3.41 | 17:284571 |