Printable factfile
Gene Information
Names
HUGO name: CD79A
Alias(es):
- IGA
- MB-1
- MB1
- CD79A antigen
- B-cell antigen receptor complex associated protein alpha-chain precursor
- MB-1 membrane glycoprotein
- Surface-IgM- associated protein
- Membrane-bound immunoglobulin associated protein
- CD79a
Variations / Mutations
Other gene-based resources
Protein Information
Description
Protein function:
Associated to surface IgM-receptor; may be involved in signal transduction.
Subunit:
Heterodimer of α and β chains, disulfide-linked.
Subcellular location:
Type I membrane protein.
Post-translational modification:
Phosphorylated on tyrosine as a result of B-cell activation.
Alternative products:
2 isoforms; a long form and a short form; are produced by alternative splicing.
Other features
Other related resourses:
Expression
Expression pattern for human
| Tissue | Expression (%) | Clones |
|---|---|---|
| lymph node | 40.61 | 1:125 |
| B-cells | 16.87 | 55:16554 |
| B cells from Burkitt lymphoma | 9.48 | 4:2143 |
| normal head/neck tissue | 7.84 | 2:1295 |
| lymph | 7.21 | 94:66155 |
| leukocyte | 3.94 | 7:9008 |
| spleen | 2.03 | 5:12529 |
| osteoarthritic cartilage | 1.68 | 1:3016 |
| thymus, pooled | 1.60 | 1:3169 |
| lymph, T-cell | 1.19 | 2:8536 |