Printable factfile
Immunoglobulin G sublass deficiency is defined as a decrease of an IgG sublass greater than 2 standard deviations below the normal mean for age. One or more IgG subclasses and other Ig isotypes may be involved. This deficiency may be isolated or associated with other immunodeficiencies (IgA deficiency, ataxia-telangiectasia).
Alternative names
Classification
- Deficiencies predominantly affecting antibody production
- Selective deficiency of IgG subclass, IgE and/or IgA class or subclass
Inheritance
Autosomal recessive
OMIM
*147130 Immunoglobulin Gm4; IGHG4
Cross references
Phenotypically related immunodeficiencies
IDR factfile for γ1 isotype deficiency
Incidence
Incidence is not known.