Printable factfile
Gene Information
Names
HUGO name: IGHA1
Alias(es):
- Immunoglobin heavy constant alpha 1
- immunoglobulin alpha 1
- Ig alpha-1 chain C region
Localization
Reference sequences
Chromosomal location
Maps
Variations / Mutations
Other gene-based resources
Protein Information
Description
Protein function:
Igα is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:
Monomeric or polymeric.
Other features
Disulfide bond interchain (with a light chain): 14
Disulfide bond: 26-85
Disulfide bond: 77-101
Disulfide bond interchain (with heavy chain): 122
Disulfide bond or 123-182: 123-180
Disulfide bond: 147-204
Disulfide bond interchain (with heavy chain): 182
Disulfide bond intersubunit bond: 192
Disulfide bond: 250-313
Disulfide bond with j chain: 352
O-linked glycosylation site: 105
O-linked glycosylation site: 111
O-linked glycosylation site: 113
O-linked glycosylation site: 119
O-linked glycosylation site: 121
Other related resourses:
Expression
Expression pattern for human
| Tissue | Expression (%) | Clones |
|---|