α2 isotype deficiency

Gene Information

Names

HUGO name: IGHA2

Alias(es):

  • Immunoglobin heavy constant alpha 2
  • A2m marker
  • Immunoglobulin alpha 2
  • A2M marker
  • Ig alpha-2 chain C region

Localization

Reference sequences

Chromosomal location

Maps

Protein Information

Description

Protein function:

Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system

Subunit:

Monomeric or polymeric

Other features

Disulfide bond: 26-85

    Disulfide bond interchain (with light chain): 101

      Disulfide bond interchain (with heavy chain): 109

        Disulfide bond: 110-167

          Disulfide bond: 134-191

            Disulfide bond interchain (with heavy chain): 169

              Disulfide bond intersubunit bond: 179

                Disulfide bond: 237-300

                  Disulfide bond with j chain: 339

                    Other related resourses:

                    Expression

                    Expression pattern for human

                    Tissue Expression (%) Clones

                    Animal models

                    Fly