ε isotype deficiency

Immunoglobulins of the IgE isotype are responsible for the immediate hypersensitivity reactions in diseases like hay fever, allergic asthma, and anaphalaxis. There are two forms of IgE, one which is secreted and one which is on the membrane lymphocytes.

Alternative names

IgE deficiency

Classification

  • Deficiencies predominantly affecting antibody production
    • Selective deficiency of IgG subclass, IgE and/or IgA class or subclass

Inheritance

OMIM

*147180 Immunoglobulin: heavy epsilon chain; IGHE

Cross references

Phenotypically related immunodeficiencies

Incidence

Incidence unknown.