ε isotype deficiency

IgE deficiency is associated with higher incidence of autoimmune diseases and nonallergic reactive airway disease.

Diagnostic laboratories

Clinical:

Genetic:

Therapeutic options

  • Only symptomatic patients should be treated. Antibiotic therapy in case there are recurrent infections followed by (intravenous) Ig if infections are not controlled.
  • Hypogammaglobulinemia, eMedicine