C4 binding protein β deficiency

Elevated plasma levels of C4BP are associated with increased risk for thromboembolic disorders, due to an inactivation of the protein C anticoagulatory pathway.

Therapeutic options

  • Fresh frozen plasma is used for emergent replacement of complements components. Supportive therapy is used for complement deficiencies. Prophylactic antibiotics for the infections.
  • Complement deficiency, eMedicine