Kappa deficiency has little if any effect on health, gamma chains seem to be able to substitute effectively. The symptoms can vary including recurrent respiratory infections and diarrhea.
Diagnosis
Additional Information
Therapeutic options
- (Intravenous) immunoglobulins and antibiotic therapy. Oral poliovaccine should not be given because of the risk of paralytic disease.
- Hypogammaglobulinemia, eMedicine
- Agammaglobulinemia, eMedicine
Research programs, clinical trials
- Improved Healthcare for Patients with Primary Antibody Deficiencies through new Strategies Elucidating their Pathophysiology (IMPAD), IMPAD
- European Initiative for Primary Immunodeficiencies
- Immune Regulation in Patients with Common Variable Immunodeficiency and Related Syndromes, ClinicalTrials.gov