Printable factfile
Gene Information
Names
HUGO name: LYST
Alias(es):
- CHS
- CHS1
- Human beige protein homolog (chs) mRNA, complete cds
- Lysosomal trafficking regulator
Localization
Reference sequences
Chromosomal location
Maps
Variations / Mutations
Other gene-based resources
Protein Information
Description
Protein function:
May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules.
Subcellular location:
Cytoplasmic (potential)
Alternative products:
At least 3 isoforms are produced by alternative splicing.
Expression
Expression pattern for human
| Tissue | Expression (%) | Clones |
|---|---|---|
| adipose, perirenal brown adipose tissue | 88.86 | 1:34 |
| human lens | 1.50 | 2:4028 |
| hypothalamus | 0.92 | 2:6565 |
| placenta human 8 week | 0.75 | 1:4035 |
| foreskin, melanocyte | 0.67 | 3:13478 |
| muscle (skeletal) | 0.63 | 2:9571 |
| testis, cell line | 0.53 | 3:16978 |
| pool, melanocyte+heart+uterus | 0.46 | 5:32944 |
| pool, liver+spleen | 0.44 | 9:61327 |
| hepatocellular carcinoma | 0.42 | 2:14226 |