Mannose-binding lectin deficiency

MBL deficiency is associated with an increased frequency of infection in both adults and children. Many patients have systemic lupus erythematous (SLE).

Therapeutic options

  • Fresh frozen plasma is used for emergent replacement of complement components. Prophylactic antibiotics for the infections. Acute infections are treated with appropriate antibiotics and prevented also with vaccination (meningococcal, pneumococcal, and haemophilus).
  • Complement deficiency, eMedicine
  • Complement deficiency, eMedicine