Printable factfile
The patients have a range of diverse autoimmune and inflammatory conditions with disturbed immune cell homeostasis. They can
have consistently exhibited dramatic lymphoproliferation and a breakdown in tolerance to multiple self-antigens leading to severe autoimmune
complications.
Diagnosis
Diagnostic recommendations
Additional Information
Therapeutic options
Research programs, clinical trials
- European Initiative for Primary Immunodeficiencies.
- APLSbase, National Human Genome Research Institute
- Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome, ClinicalTrial.gov
- Study of Autoimmune Lymphoproliferative Syndrome (ALPS), ClinicalTrial.gov
- Genetic Analysis of Immune Disorders, ClinicalTrial.gov