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The clinical symptoms are similar with those for SCID: failure to thrive, intractable diarrhea, and recurrent lung infection. The patients had an early arrest in T cell development, with a nearly complete absence of circulating mature T cells and a complete absence of gamma/delta T cells.
Diagnosis
Diagnostic recommendations
Additional Information
Diagnostic laboratories
Clinical:
Genetic:
Therapeutic options
- Treatment of infections with antibacterials, antifungals, and antivirals. Bone marrow transplantation is the only treatment of SCID. Other recommendations include: intravenous gamma-globulin infusion, irradiation of all blood products.
- Severe combined immunodeficiency, eMedicine