p56 Lck deficiency

p56 Lck deficiency is a unique form of SCID with selective CD4 lymphopenia and reduced production of the p56lck protein. A chromosomal aberration involving LCK is found also in leukemias.

Alternative names

CD4 deficiency-LCK

Classification

  • Combined B and T cell immunodeficiencies
    • Other

Inheritance

Autosomal recessive

OMIM

*153390 Lymphocyte-specific protein-tyrosine kinase; LCK

Cross references

Phenotypically related immunodeficiencies

IDR factfile for JAK3 deficiency

IDR factfile for X-linked SCID(gamma-chain deficiency)

Incidence

Incidence is not known.