Granulomatous sinovitis with uveitis and cranial neuropathies

Defects in CARD15 are the cause of Blau syndrome, an autosomal dominant disorder characterized by early-onset granulomatous arthritis, uveitis and skin rash.

Alternative names

BS, ACUG

Blau syndrome

Granulomatosis, familial juvenile systemic

Arthrocutaneouveal granulomatosis

Jabs syndrome

Granulomatous inflammatory arthritis, dermatitis, and uveitis, familial

Granulomatosis, familial, Blau type

Jabs houk bias syndrome

Synovitis granulomatous uveitis cranial neuropathies

Classification

  • Periodic fever syndromes

Inheritance

Autosomal dominant

OMIM

#186580 Synovitis, granulomatous, with uveitis and cranial neuropathies

*605956 Caspase recruitment domain-containing protein 15; CARD15

Incidence

Incidence is not known.