Patients have diarrhea, abdominal pain, rectal bleeding, anorexia, weight loss. Extra digestive manifestations may occur in parallel with the digestive symptoms during attacks such as fever, arthralgia, arthritis, buccal aphtosis, erythema nodosa, pyoderma gangrenosum, iritis, episcleritis.
Diagnosis
Diagnostic recommendations
Additional Information
- Crohn disease, eMedicine
- Crohn disease, ORPHANET
- Crohn disease, Dermatologie Online Atlas
- Crohn disease, Fondation pour la Recherche Medicale
- Crohn disease, INFEVERS (INternet periodic FEVERS)
- Crohn disease, Medicine-Worldwide
- Crohn disease, National Institute of Diabetes and Digestive and Kidney Diseases
- Periodic fever-comparisons, Dr. Sullivan K.
Therapeutic options
- The main drugs are salicylates, steroids, immunomodulators. Surgery is often required for treatment of bowel stenosis, abscess, internal fistula, as well as ano-perineal manifestations of the disease. Patients may require either enteral or parenteral nutrition.
- Crohn disease, eMedicine