Crohn's disease

Patients have diarrhea, abdominal pain, rectal bleeding, anorexia, weight loss. Extra digestive manifestations may occur in parallel with the digestive symptoms during attacks such as fever, arthralgia, arthritis, buccal aphtosis, erythema nodosa, pyoderma gangrenosum, iritis, episcleritis.

Therapeutic options

  • The main drugs are salicylates, steroids, immunomodulators. Surgery is often required for treatment of bowel stenosis, abscess, internal fistula, as well as ano-perineal manifestations of the disease. Patients may require either enteral or parenteral nutrition.
  • Crohn disease, eMedicine

Research programs, clinical trials