Familial haemophagocytic lymphohistiocytosis type 4

Gene Information

Names

HUGO name: STX11

Localization

Reference sequences

Chromosomal location

Maps

Protein Information

Description

Protein function:

Snare that acts to regulate protein transport between late endosomes and the trans-golgi network.

Subunit:

Interacts with the snare proteins SNAP-23 and VAMP.

Subcellular location:

Membrane; peripheral membrane protein (potential).

Similarity:

Belongs to the syntaxin family.

Structures (PDB)

Expression

Expression pattern for human

Tissue Expression (%) Clones
lymph_node 34.66 15:83039
bone_marrow 18.56 4:41353
placenta 11.08 11:190488
mixed 8.64 13:288723
uncharacterized_tissue 5.34 6:215582
small_intestine 4.48 1:42840
unclassified 4.08 2:94133
blood 3.12 1:61437
lung 2.66 4:288686
connective_tissue 2.00 1:96057

Animal models

Mouse