λ5 surrogate light-chain deficiency

Gene Information

Names

HUGO name: IGLL1

Alias(es):

  • IGL1
  • IGL5
  • IGLL
  • IGO
  • IGVPB
  • immunoglobulin lambda-like polypeptide 1, pre-B-cell specific
  • Immunoglobulin lambda-like polypeptide 1 precursor
  • Immunoglobulin- related 14.1 protein
  • Immunoglobulin omega polypeptide

Localization

Reference sequences

Chromosomal location

Maps

Protein Information

Description

Subunit:

Associates non-covalently with vpreb1

Structures (PDB)

Domains

J region (by similarity to lambda light-chain) domain: 97-108

    C region (by similarity to lambda light-chain) domain: 109-213

      Other features

      Signal peptide: 1-37

        Immunoglobulin lambda-like polypeptide 1: 38-213

          Other related resourses:

          Expression

          Expression pattern for human

          Tissue Expression (%) Clones
          colonic mucosa with ulcerative colitus 37.51 1:1218
          cord blood 17.67 3:7759
          bone marrow 16.11 7:19854
          thymus, pooled 14.42 1:3169
          leukopheresis 10.03 1:4557
          testis 2.64 5:86533
          heart 1.24 1:36928
          kidney 0.39 1:117548

          Animal models

          Mouse

          C. elegans