γ1 isotype deficiency

Gene Information

Names

HUGO name: IGHG1

Alias(es):

  • Immunoglobin heavy constant gamma 1 (G1m marker)
  • immunoglobulin gamma 1 (Gm marker)
  • Ig gamma-1 chain C region

Localization

Reference sequences

Chromosomal location

Maps

Protein Information

Description

Miscellaneous:

Nie has the g1m(17) allotypic marker, 97-k, & the g1m(1) markers, 239-d & 241-l. Kol & eu sequences have the g1m(3) marker & the g1m (non-1) markers.

Structures (PDB)

1FC1 Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.
1FC2 Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution.

Domains

Ch1 domain: 1-98

    Hinge domain: 99-110

      Ch2 domain: 111-223

        Ch3 domain: 224-330

          Other features

          Disulfide bond: 27-83

            Disulfide bond interchain (with light chain): 103

              Disulfide bond interchain (with heavy chain): 109

                Disulfide bond interchain (with heavy chain): 112

                  Disulfide bond: 144-204

                    Disulfide bond: 250-308

                      Other related resourses:

                      Expression

                      Expression pattern for human

                      Animal models

                      Mouse

                      Fly