Printable factfile
The most common clinical presentation of C1r/C1s deficiency is systemic lupus eritematous
(SLE), although bacterial infections and glomerulonephritis are also common in this patient population.
Diagnosis
Diagnostic recommendations
Additional Information
Therapeutic options
- Fresh frozen plasma is used for emergent replacement of complements components. Supportive therapy is used for complement deficiencies. Prophylactic antibiotics for the infections.
- Complement deficiency, eMedicine
- Complement deficiency, eMedicine