C6 deficiency

The most common form of C6 deficiency is characterised by undetectable levels of C6. Subtotal deficiency of C6(C6SD) is characterised by 1%-2% of the normal serum antigenic levels of C6. Subtotal deficiency of C6 has also been seen in association with subtotal C7 deficiency.

Alternative names

Complement component 6 deficiency

Classification

  • Defects of the classical complement cascade proteins

Inheritance

Autosomal recessive