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Patients with C6 deficiency lack serum bactericidal activity and most commonly present with systemic blood-born meningococcal infections. Disseminated gonococcal infections have rarely been described. Few patients with C6 deficiencies present systemic lupus erythematous(SLE).
Diagnosis
Diagnostic recommendations
Additional Information
Therapeutic options
- Fresh frozen plasma is used for emergent replacement of complements components. Supportive therapy is used for complement deficiencies. Prophylactic antibiotics for the infections. Autoimmune disease is treated in the normal way.
- Complement deficiency, eMedicine
- Complement deficiency, eMedicine