Printable factfile
Systemic neisserial infections occur in 60% of reported cases of C7-deficient patients. Other manifestation include SLE, rheumatoid arthritis, pyoderma gangrenosum, and scleroderma.
Diagnosis
Diagnostic recommendations
Additional Information
Therapeutic options
- Fresh frozen plasma is used for emergent replacement of complements components. Supportive therapy is used for complement deficiencies. Prophylactic antibiotics for the infections. Specific treatment of autoimmune disease is needed.
- Complement deficiency, eMedicine
- Complement deficiency, eMedicine