Printable factfile
Mutation of the CD19 gene causes a type of hypogammaglobulinemia with a defective response of mature B cells to antigenic stimulation. CD19 protein forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells.
Alternative names
CD19D
Antibody deficiency due to defect in CD19
Classification
- Deficiencies predominantly affecting antibody production
- Other antibody deficiencies
Inheritance
Autosomal recessive
OMIM
+107265 Cd19 antigen; CD19
Cross references
Phenotypically related immunodeficiencies
IDR factfile for Common variable immunodeficiency of unknown origin
Incidence
Incidence is not known yet.